This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name : 
Novus Biologicals
other brands : 
IMGENEX
product type : 
antibody
product name : 
Mouse Monoclonal TLR9 Antibody (26C593.2) [Biotin]
catalog : 
NBP2-24890
quantity : 
0.1 ml
price : 
369 USD
clonality : 
monoclonal
host : 
mouse
conjugate : 
biotin
clone name : 
26C593.2
reactivity : 
human, mouse, rat, dog
application : 
immunohistochemistry - paraffin section
citations: 49
| Published Application/Species/Sample/Dilution | Reference | 
|---|---|
| 
 | |
| Dasgupta G, Chentoufi A, You S, Falatoonzadeh P, Urbano L, Akhtarmalik A, et al. Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci. 2011;52:3321-33 pubmed  publisher  | |
| Sacre S, Lo A, Gregory B, Simmonds R, Williams L, Feldmann M, et al. Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures. J Immunol. 2008;181:8002-9 pubmed  | |
| Cognasse F, Hamzeh Cognasse H, Lafarge S, Chavarin P, Pozzetto B, Richard Y, et al. Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. Immunology. 2008;125:430-7 pubmed  publisher  | |
| Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, et al. Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway. J Immunol. 2008;180:4067-74 pubmed  | |
| Pegu A, Qin S, Fallert Junecko B, Nisato R, Pepper M, Reinhart T. Human lymphatic endothelial cells express multiple functional TLRs. J Immunol. 2008;180:3399-405 pubmed  | |
| Nakano S, Morimoto S, Suzuki J, Nozawa K, Amano H, Tokano Y, et al. Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus. Rheumatology (Oxford). 2008;47:145-9 pubmed  | |
| Tran N, Koch A, Berkels R, Boehm O, Zacharowski P, Baumgarten G, et al. Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation. J Clin Endocrinol Metab. 2007;92:2773-83 pubmed  | |
| Kindrachuk J, Potter J, Brownlie R, Ficzycz A, Griebel P, Mookherjee N, et al. Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9. J Biol Chem. 2007;282:13944-53 pubmed  | |
| Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed  | |
| Palladino M, Johnson T, Gupta R, Chapman J, Ojha P. Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract. Biol Reprod. 2007;76:958-64 pubmed  | |
| Lee J, Mo J, Katakura K, Alkalay I, Rucker A, Liu Y, et al. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol. 2006;8:1327-36 pubmed  | |
| Mansson A, Adner M, Cardell L. Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Respir Res. 2006;7:36 pubmed  | |
| Miller L, Sørensen O, Liu P, Jalian H, Eshtiaghpour D, Behmanesh B, et al. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. J Immunol. 2005;174:6137-43 pubmed  | |
| Abel K, Wang Y, Fritts L, Sanchez E, Chung E, Fitzgerald Bocarsly P, et al. Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoi. Clin Diagn Lab Immunol. 2005;12:606-21 pubmed  | 
product information
Catalog Number : 
NBP2-24890
Product Name : 
Mouse Monoclonal TLR9 Antibody (26C593.2) [Biotin]
List Price : 
369 USD
product type : 
Primary Antibodies
Package Size : 
0.1 ml
AltNames : 
CD289, CD289 antigen, toll-like receptor 9
Buffer : 
PBS
Clonality : 
Monoclonal
Clone : 
26C593.2
Conjugate : 
Biotin
Application Summary : 
ELISA
Host : 
Mouse
Immunogen : 
This antibody was developed against KLH-conjugated synthetic peptide corresponding to amino acids 268-300 of human TLR9 isoform A (Genbank accession no. AAF78037).
Isotype : 
IgG1 Kappa
Preservative : 
0.05% Sodium Azide
Purity : 
Protein G purified
CrossReactivity : 
Canine, Equine, Human, Mouse, Primate, Rat
Storage : 
Store at 4C. Do not freeze.
Swissprot Human : 
Q9NR96
Uses : 
Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.  In human PBMC, a ~120 kDa band is observed. A smaller isoform, TLR9 isoform B (Genbank accession no. AAF72190) containing 975 amino acids may also be observed in some cases.
Research Area : 
Cytokine Research, Immunology, Innate Immunity, Toll Like Receptors
company information

Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.
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