product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CD3 Antibody (OKT3) - Low Endotoxin, Azide and BSA Free
catalog :
NBP2-24867
quantity :
0.1 mg (also 0.025 mg)
price :
349 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OKT3
reactivity :
human, mouse
application :
western blot, flow cytometry
more info or order :
citations: 8
Reference
Ma S, Xu X, Jones R, Delecluse H, Zumwalde N, Sharma A, et al. PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model. PLoS Pathog. 2016;12:e1005642 pubmed publisher
Whitehurst C, Li G, Montgomery S, Montgomery N, Su L, Pagano J. Knockout of Epstein-Barr virus BPLF1 retards B-cell transformation and lymphoma formation in humanized mice. MBio. 2015;6:e01574-15 pubmed publisher
Kim S, Lowe E, Dixit D, Youn C, Kim I, Jung J, et al. Cocaine-mediated impact on HIV infection in humanized BLT mice. Sci Rep. 2015;5:10010 pubmed publisher
Amelio I, Inoue S, Markert E, Levine A, Knight R, Mak T, et al. TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation. Proc Natl Acad Sci U S A. 2015;112:226-31 pubmed publisher
Ma S, Xu X, Plowshay J, Ranheim E, Burlingham W, Jensen J, et al. LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis. J Clin Invest. 2015;125:304-15 pubmed publisher
Gill T, Levine A. Mitochondria-derived hydrogen peroxide selectively enhances T cell receptor-initiated signal transduction. J Biol Chem. 2013;288:26246-55 pubmed publisher
Ma S, Yu X, Mertz J, Gumperz J, Reinheim E, Zhou Y, et al. An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model. J Virol. 2012;86:7976-87 pubmed publisher
Crellin N, Garcia R, Hadisfar O, Allan S, Steiner T, Levings M. Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J Immunol. 2005;175:8051-9 pubmed
product information
master code :
NBP2-24867
SKU :
NBP2-24867
product name :
CD3 Antibody (OKT3) - Low Endotoxin, Azide and BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The CD3 Antibody (OKT3) - Low Endotoxin, Azide and BSA Free from Novus is a mouse monoclonal antibody to CD3. This antibody reacts with human,mouse. The CD3 Antibody (OKT3) - Low Endotoxin, Azide and BSA Free has been validated for the following applications: Flow Cytometry,In vitro assay,In vivo assay,Functional Assay,Functional,Immunoblotting,Flow (Cell Surface),CyTOF-ready.
target :
CD3
category :
Primary Antibodies
buffer :
Filter sterilized PBS.
clonality :
Monoclonal
clone :
OKT3
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This CD3 antibody was developed against human PBMCs.
isotype :
IgG2a Kappa
purity :
Protein G purified
species :
Human,Mouse
theoretical molecular weight :
23.1 kDa
gene symbol :
CD3E
endotoxin note :
Endotoxin amounts will vary lot to lot, but should be less than 0.03 EU/ug.
applications :
Flow Cytometry,In vitro assay,In vivo assay,Functional Assay,Functional,Immunoblotting,Flow (Cell Surface),CyTOF-ready
extended description :
Clone OKT3 was used by HLDA to establish CD designation.
USD :
349 USD
product details :
Clone OKT3 was used by HLDA to establish CD designation.
alt names :
anti-CD3 okt3, CD_antigen: CD3e, CD3 antigen, delta subunit, CD3d antigen, CD3d antigen, delta polypeptide (TiT3 complex), CD3d molecule, delta (CD3-TCR complex), CD3-DELTA, CD3e, CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, CD3G, CD3g antigen, CD3g antigen, gamma polypeptide (TiT3 complex), CD3g molecule, epsilon (CD3-TCR complex), CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, FLJ17620, FLJ17664, FLJ18683, FLJ79544, FLJ94613, IMD18, MGC138597, Muromonab, okt3, okt3 ab, okt3 CD3, okt3 hybridoma, T3DOKT3, delta chain, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell receptor T3 delta chain, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.