TLR4 Antibody (MTS510) - Azide and BSA Free | Novus Biologicals NBP2-24865 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TLR4 Antibody (MTS510) - Azide and BSA Free

catalog :

NBP2-24865

quantity :

0.1 mg (also 0.025 mg)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

MTS510

reactivity :

human, mouse

application :

western blot, immunocytochemistry, neutralization, flow cytometry

more info or order :

Novus Biologicals product webpage

citations: 12

Reference
Tsai C, Lin C, Tsai H, Chen C, Li W, Yu H, et al. The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling. J Biol Chem. 2013;288:17689-97 pubmed publisher
Kim M, Shu Y, Carsillo T, Zhang J, Yu L, Peterson C, et al. hsp70 and a novel axis of type I interferon-dependent antiviral immunity in the measles virus-infected brain. J Virol. 2013;87:998-1009 pubmed publisher
Ma C, Shi G, Shi C, Kao Y, Lin S, Wu H. Monocytic thrombomodulin triggers LPS- and gram-negative bacteria-induced inflammatory response. J Immunol. 2012;188:6328-37 pubmed publisher
Bruscia E, Zhang P, Satoh A, Caputo C, Medzhitov R, Shenoy A, et al. Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. J Immunol. 2011;186:6990-8 pubmed publisher
Park H, Hong J, Kwon H, Kim Y, Lee K, Kim J, et al. TLR4-mediated activation of mouse macrophages by Korean mistletoe lectin-C (KML-C). Biochem Biophys Res Commun. 2010;396:721-5 pubmed publisher
Tsukamoto H, Fukudome K, Takao S, Tsuneyoshi N, Kimoto M. Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells. Int Immunol. 2010;22:271-80 pubmed publisher
Macedo G, Magnani D, Carvalho N, Bruna Romero O, Gazzinelli R, Oliveira S. Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection. J Immunol. 2008;180:1080-7 pubmed
Corbucci C, Cenci E, Skrzypek F, Gabrielli E, Mosci P, Ernst J, et al. Immune response to Candida albicans is preserved despite defect in O-mannosylation of secretory proteins. Med Mycol. 2007;45:709-19 pubmed
El Shikh M, El Sayed R, Wu Y, Szakal A, Tew J. TLR4 on follicular dendritic cells: an activation pathway that promotes accessory activity. J Immunol. 2007;179:4444-50 pubmed
Konno K, Wakabayashi Y, Akashi Takamura S, Ishii T, Kobayashi M, Takahashi K, et al. A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression. Biochem Biophys Res Commun. 2006;339:1076-82 pubmed
Schaefer L, Babelova A, Kiss E, Hausser H, Baliova M, Krzyzankova M, et al. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest. 2005;115:2223-33 pubmed
Jung D, Lee H, Jung B, Ock J, Lee M, Lee W, et al. TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker. J Immunol. 2005;174:6467-76 pubmed

product information

master code :

NBP2-24865

SKU :

NBP2-24865

product name :

TLR4 Antibody (MTS510) - Azide and BSA Free

unit size :

0.1 mg (also 0.025 mg)

description :

The TLR4 Antibody (MTS510) - Azide and BSA Free from Novus is a rat monoclonal antibody to TLR4. This antibody reacts with human,mouse. The TLR4 Antibody (MTS510) - Azide and BSA Free has been validated for the following applications: Flow Cytometry,Western Blot,Flow (Cell Surface),Immunocytochemistry/ Immunofluorescence,CyTOF-ready,Block/Neutralize.

target :

TLR4

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

MTS510

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rat

immunogen :

This TLR4 Antibody (MTS510) was developed by immunizing rats with the Ba/F3 cell line expressing mouse TLR4 and MD-2 (Akashi et al, 2000).

isotype :

IgG2a Kappa

purity :

Protein G purified

species :

Human,Mouse

specificity :

This antibody preferentially recognizes TLR4-MD-2 complex than of TLR4 alone

theoretical molecular weight :

95.7 kDa

gene symbol :

TLR4

applications :

Flow Cytometry,Western Blot,Flow (Cell Surface),Immunocytochemistry/ Immunofluorescence,CyTOF-ready,Block/Neutralize

USD :

459 USD

alt names :

ARMD10, CD_antigen: CD284, CD284, CD284 antigen, EC 3.2.2.6, EC:3.2.2.6, homolog of Drosophila toll, hToll, TLR4, TLR-4, TOLL, toll like receptor 4 protein, toll-like receptor 4

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage