TLR9 Antibody (26C593.2) - Azide Free | Novus Biologicals NBP2-24863 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TLR9 Antibody (26C593.2) - Azide Free

catalog :

NBP2-24863

quantity :

0.1 mg

price :

519 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

26C593.2

reactivity :

human, mouse, rat, dogs, rhesus macaque

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 53

Reference
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Guerrier T, Pochard P, Lahiri A, Youinou P, Pers J, Jamin C. TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response. J Autoimmun. 2014;51:23-9 pubmed publisher
Belmont L, Rabbe N, Antoine M, Cathelin D, Guignabert C, Kurie J, et al. Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer. Int J Cancer. 2014;134:765-77 pubmed publisher
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Dasgupta G, Chentoufi A, You S, Falatoonzadeh P, Urbano L, Akhtarmalik A, et al. Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci. 2011;52:3321-33 pubmed publisher
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Myles A, Aggarwal A. Expression of Toll-like receptors 2 and 4 is increased in peripheral blood and synovial fluid monocytes of patients with enthesitis-related arthritis subtype of juvenile idiopathic arthritis. Rheumatology (Oxford). 2011;50:481-8 pubmed publisher
Schneberger D, Lewis D, Caldwell S, Singh B. Expression of toll-like receptor 9 in lungs of pigs, dogs and cattle. Int J Exp Pathol. 2011;92:1-7 pubmed publisher
Wang C, Cao S, Yan Y, Ying Q, Jiang T, Xu K, et al. TLR9 expression in glioma tissues correlated to glioma progression and the prognosis of GBM patients. BMC Cancer. 2010;10:415 pubmed publisher
Booth J, Arsenault R, Napper S, Griebel P, Potter A, Babiuk L, et al. TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides. J Innate Immun. 2010;2:483-94 pubmed publisher
Keestra A, de Zoete M, Bouwman L, van Putten J. Chicken TLR21 is an innate CpG DNA receptor distinct from mammalian TLR9. J Immunol. 2010;185:460-7 pubmed publisher
Jukkola Vuorinen A, Rahko E, Vuopala K, Desmond R, Lehenkari P, Harris K, et al. Toll-like receptor-9 expression is inversely correlated with estrogen receptor status in breast cancer. J Innate Immun. 2009;1:59-68 pubmed publisher
Machida H, Ito S, Hirose T, Takeshita F, Oshiro H, Nakamura T, et al. Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis. Nephrol Dial Transplant. 2010;25:2530-537 pubmed publisher
Kim Y, Park J, Brand D, Fitzpatrick E, Yi A. Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula. J Immunol. 2010;184:3145-56 pubmed publisher
Panda A, Qian F, Mohanty S, van Duin D, Newman F, Zhang L, et al. Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol. 2010;184:2518-27 pubmed publisher
Chentoufi A, Dasgupta G, Nesburn A, Bettahi I, Binder N, Choudhury Z, et al. Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization. Clin Vaccine Immunol. 2010;17:342-53 pubmed publisher
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. 2010;129:363-74 pubmed publisher
Zhou M, McFarland Mancini M, Funk H, Husseinzadeh N, Mounajjed T, Drew A. Toll-like receptor expression in normal ovary and ovarian tumors. Cancer Immunol Immunother. 2009;58:1375-85 pubmed publisher
Palladino M, Savarese M, Chapman J, Dughi M, Plaska D. Localization of Toll-like receptors on epididymal epithelial cells and spermatozoa. Am J Reprod Immunol. 2008;60:541-55 pubmed publisher
Meneghin A, Choi E, Evanoff H, Kunkel S, Martinez F, Flaherty K, et al. TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation. Histochem Cell Biol. 2008;130:979-92 pubmed publisher
Cohen P, Koski G, Czerniecki B, Bunting K, Fu X, Wang Z, et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 2008;112:1832-43 pubmed publisher
Selleri S, Palazzo M, Deola S, Wang E, Balsari A, Marincola F, et al. Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS. Int Immunol. 2008;20:961-70 pubmed publisher
Ju X, Zenke M, Hart D, Clark G. CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. Blood. 2008;112:1184-94 pubmed publisher
Zhang Y, Davis E, Blecha F, Wilkerson M. Molecular cloning and characterization of equine Toll-like receptor 9. Vet Immunol Immunopathol. 2008;124:209-19 pubmed publisher
Cognasse F, Hamzeh Cognasse H, Lafarge S, Chavarin P, Pozzetto B, Richard Y, et al. Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. Immunology. 2008;125:430-7 pubmed publisher
Burgener I, Jungi T. Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol. 2008;124:184-91 pubmed publisher
Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, et al. Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway. J Immunol. 2008;180:4067-74 pubmed
Pegu A, Qin S, Fallert Junecko B, Nisato R, Pepper M, Reinhart T. Human lymphatic endothelial cells express multiple functional TLRs. J Immunol. 2008;180:3399-405 pubmed
Meng Y, Kujas M, Marie Y, Paris S, Thillet J, Delattre J, et al. Expression of TLR9 within human glioblastoma. J Neurooncol. 2008;88:19-25 pubmed publisher
Nakano S, Morimoto S, Suzuki J, Nozawa K, Amano H, Tokano Y, et al. Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus. Rheumatology (Oxford). 2008;47:145-9 pubmed
Tran N, Koch A, Berkels R, Boehm O, Zacharowski P, Baumgarten G, et al. Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation. J Clin Endocrinol Metab. 2007;92:2773-83 pubmed
Kindrachuk J, Potter J, Brownlie R, Ficzycz A, Griebel P, Mookherjee N, et al. Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9. J Biol Chem. 2007;282:13944-53 pubmed
Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed
Ewaschuk J, Backer J, Churchill T, Obermeier F, Krause D, Madsen K. Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA. Infect Immun. 2007;75:2572-9 pubmed
Palladino M, Johnson T, Gupta R, Chapman J, Ojha P. Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract. Biol Reprod. 2007;76:958-64 pubmed
Lee J, Mo J, Katakura K, Alkalay I, Rucker A, Liu Y, et al. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol. 2006;8:1327-36 pubmed
Niessner A, Sato K, Chaikof E, Colmegna I, Goronzy J, Weyand C. Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation. 2006;114:2482-9 pubmed
Mansson A, Adner M, Cardell L. Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Respir Res. 2006;7:36 pubmed
Gottenberg J, Cagnard N, Lucchesi C, Letourneur F, Mistou S, Lazure T, et al. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. Proc Natl Acad Sci U S A. 2006;103:2770-5 pubmed
Martin Armas M, Simon Santamaria J, Pettersen I, Moens U, Smedsrød B, Sveinbjørnsson B. Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides. J Hepatol. 2006;44:939-46 pubmed
Lee J, Wu C, Lee K, Chuang T, Katakura K, Liu Y, et al. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci U S A. 2006;103:1828-33 pubmed
Damiano V, Caputo R, Bianco R, D Armiento F, Leonardi A, De Placido S, et al. Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors. Clin Cancer Res. 2006;12:577-83 pubmed
Tabeta K, Hoebe K, Janssen E, Du X, Georgel P, Crozat K, et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol. 2006;7:156-64 pubmed
Srivastava M, Srivastava B. Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line. Leuk Res. 2005;29:813-20 pubmed
Miller L, Sørensen O, Liu P, Jalian H, Eshtiaghpour D, Behmanesh B, et al. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. J Immunol. 2005;174:6137-43 pubmed
Abel K, Wang Y, Fritts L, Sanchez E, Chung E, Fitzgerald Bocarsly P, et al. Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoi. Clin Diagn Lab Immunol. 2005;12:606-21 pubmed
Cognasse F, Hamzeh H, Chavarin P, Acquart S, Genin C, Garraud O. Evidence of Toll-like receptor molecules on human platelets. Immunol Cell Biol. 2005;83:196-8 pubmed
Greene C, Carroll T, Smith S, Taggart C, Devaney J, Griffin S, et al. TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells. J Immunol. 2005;174:1638-46 pubmed
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product information

master code :

NBP2-24863

SKU :

NBP2-24863

product name :

TLR9 Antibody (26C593.2) - Azide Free

unit size :

0.1 mg

description :

The TLR9 Antibody (26C593.2) - Azide and BSA Free from Novus is a mouse monoclonal antibody to TLR9. This antibody reacts with canine,equine,human,monkey,mouse,primate,primate (rhesus monkey),rat. The TLR9 Antibody (26C593.2) - Azide and BSA Free has been validated for the following applications: Flow Cytometry Control,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vitro assay,Flow Cytometry,ELISA,Immunohistochemistry,Immunoprecipitation,Functional,Flow (Cell Surface),Flow (Intracellular),Simple Western,CyTOF-ready,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.

target :

TLR9

category :

Primary Antibodies

buffer :

Sterile - filtered PBS

clonality :

Monoclonal

clone :

26C593.2

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This antibody was developed against KLH-conjugated synthetic peptide corresponding to amino acids 268-300 of human TLR9 isoform A (Genbank accession no. AAF78037).

isotype :

IgG1 Kappa

purity :

Protein G purified

species :

Canine,Equine,Human,Monkey,Mouse,Primate,Primate (Rhesus monkey),Rat

gene symbol :

TLR9

applications :

Flow Cytometry Control,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vitro assay,Flow Cytometry,ELISA,Immunohistochemistry,Immunoprecipitation,Functional,Flow (Cell Surface),Flow (Intracellular),Simple Western,CyTOF-ready,Knockdown Validated,Immunocytochemistry/ Immunofluorescence

USD :

519 USD

alt names :

CD289, CD289 antigen, toll-like receptor 9

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage