Mouse Monoclonal IkB-alpha Antibody (6A920) [Biotin] | Novus Biologicals NBP2-24815 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Mouse Monoclonal IkB-alpha Antibody (6A920) [Biotin]

catalog :

NBP2-24815

quantity :

0.1 ml

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

6A920

reactivity :

human, mouse, rat

citations: 10

Reference
Pejanovic N, Hochrainer K, Liu T, Aerne B, Soares M, Anrather J. Regulation of nuclear factor ?B (NF-?B) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT). PLoS ONE. 2012;7:e42020 pubmed publisher
Delhase M, Kim S, Lee H, Naiki Ito A, Chen Y, Ahn E, et al. TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2. Proc Natl Acad Sci U S A. 2012;109:E177-86 pubmed publisher
Harikumar K, Sung B, Pandey M, Guha S, Krishnan S, Aggarwal B. Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway. Mol Pharmacol. 2010;77:818-27 pubmed publisher
Xia Y, Ye B, Li Y, Wang J, He X, Lin X, et al. Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50. J Immunol. 2004;173:4207-17 pubmed
Saccani S, Marazzi I, Beg A, Natoli G. Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. J Exp Med. 2004;200:107-13 pubmed
Ikezoe T, Yang Y, Heber D, Taguchi H, Koeffler H. PC-SPES: a potent inhibitor of nuclear factor-kappa B rescues mice from lipopolysaccharide-induced septic shock. Mol Pharmacol. 2003;64:1521-9 pubmed
Saccani S, Pantano S, Natoli G. Modulation of NF-kappaB activity by exchange of dimers. Mol Cell. 2003;11:1563-74 pubmed
Han H, Karabiyikoglu M, Kelly S, Sobel R, Yenari M. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. J Cereb Blood Flow Metab. 2003;23:589-98 pubmed
Saccani S, Pantano S, Natoli G. p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat Immunol. 2002;3:69-75 pubmed
Saccani S, Pantano S, Natoli G. Two waves of nuclear factor kappaB recruitment to target promoters. J Exp Med. 2001;193:1351-9 pubmed

product information

Catalog Number :

NBP2-24815

Product Name :

Mouse Monoclonal IkB-alpha Antibody (6A920) [Biotin]

List Price :

369 USD

product type :

Primary Antibodies

Package Size :

0.1 ml

AltNames :

alpha, I-kappa-B-alpha, IkappaBalphaNF-kappa-B inhibitor alpha, IKBAikB-alpha, IkB-alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NFKBI, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor

Buffer :

PBS

Clonality :

Monoclonal

Clone :

6A920

Conjugate :

Biotin

Application Summary :

ELISA

Host :

Mouse

Immunogen :

A recombinant protein corresponding to amino acid residues 32-291 of human IkBa was used as immunogen.

Isotype :

IgG1 Kappa

Preservative :

0.05% Sodium Azide

Purity :

Protein G purified

CrossReactivity :

Human, Mouse, Rat

Specificity :

A 40 kDa band is observed.

Storage :

Store at 4C. Do not freeze.

Swissprot Human :

P25963

Research Area :

Apoptosis, Cell Biology, Diabetes Research, DNA Repair, Nucleotide Excision Repair, Signal Transduction