product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TLR9 Antibody (26C593.2) - BSA Free
catalog :
NBP2-24729
quantity :
0.1 mg (also 0.025 mg)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
26C593.2
reactivity :
human, mouse, rat, dogs
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, dot blot
more info or order :
citations: 152
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 1b
Lim J, Kim H, Nguyen K, Cho K. The role of TLR9 in stress-dependent autophagy formation. Biochem Biophys Res Commun. 2016;481:219-226 pubmed publisher
  • immunohistochemistry; mouse; 1:150; loading ...; fig 3i
  • western blot; mouse; 1:150; loading ...; fig s1
  • immunohistochemistry; human; 1:150; loading ...; fig 2i
  • western blot; human; 1:150; loading ...; fig s1
Huhta H, Helminen O, Kauppila J, Salo T, Porvari K, Saarnio J, et al. The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer. J Histochem Cytochem. 2016;64:470-82 pubmed publisher
  • immunocytochemistry; mouse; 1:250; fig s5
Acharya M, Sokolovska A, Tam J, Conway K, Stefani C, Raso F, et al. αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016;7:10917 pubmed publisher
  • immunoprecipitation; human
  • western blot; human
Saito K, Kukita K, Kutomi G, Okuya K, Asanuma H, Tabeya T, et al. Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE. Eur J Immunol. 2015;45:2028-41 pubmed publisher
  • immunohistochemistry - paraffin section; human
Huhta H, Helminen O, Kauppila J, Takala H, Metsikkö K, Lehenkari P, et al. Toll-like receptor 9 expression in the natural history of Barrett mucosa. Virchows Arch. 2015;467:9-18 pubmed publisher
  • immunohistochemistry - paraffin section; human
Kauppila J, Korvala J, Siirilä K, Manni M, Mäkinen L, Hagstrom J, et al. Toll-like receptor 9 mediates invasion and predicts prognosis in squamous cell carcinoma of the mobile tongue. J Oral Pathol Med. 2015;44:571-7 pubmed publisher
  • flow cytometry; human
Bharti D, Kumar A, Mahla R, Kumar S, Ingle H, Shankar H, et al. The role of TLR9 polymorphism in susceptibility to pulmonary tuberculosis. Immunogenetics. 2014;66:675-81 pubmed publisher
  • immunohistochemistry - paraffin section; human
Fehri E, Ennaifer E, Ardhaoui M, Ouerhani K, Laassili T, Bel Haj Rhouma R, et al. Expression of Toll-like receptor 9 increases with progression of cervical neoplasia in Tunisian women--a comparative analysis of condyloma, cervical intraepithelial neoplasia and invasive carcinoma. Asian Pac J Cancer Prev. 2014;15:6145-50 pubmed
  • immunohistochemistry - paraffin section; human
  • immunocytochemistry; human
Tengroth L, Millrud C, Kvarnhammar A, Kumlien Georén S, Latif L, Cardell L. Functional effects of Toll-like receptor (TLR)3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells. PLoS ONE. 2014;9:e98239 pubmed publisher
  • western blot; human
Ruan M, Thorn K, Liu S, Li S, Yang W, Zhang C, et al. The secretion of IL-6 by CpG-ODN-treated cancer cells promotes T-cell immune responses partly through the TLR-9/AP-1 pathway in oral squamous cell carcinoma. Int J Oncol. 2014;44:2103-10 pubmed publisher
  • western blot; human
Ruan M, Zhang Z, Li S, Yan M, Liu S, Yang W, et al. Activation of Toll-like receptor-9 promotes cellular migration via up-regulating MMP-2 expression in oral squamous cell carcinoma. PLoS ONE. 2014;9:e92748 pubmed publisher
  • immunocytochemistry; mouse
Veselits M, Tanaka A, Lipkowitz S, O Neill S, Sciammas R, Finnegan A, et al. Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes. PLoS ONE. 2014;9:e89792 pubmed publisher
  • immunocytochemistry; human
Zufferey A, Schvartz D, Nolli S, Reny J, Sanchez J, Fontana P. Characterization of the platelet granule proteome: evidence of the presence of MHC1 in alpha-granules. J Proteomics. 2014;101:130-40 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human
Korvala J, Harjula T, Siirilä K, Almangush A, Aro K, Makitie A, et al. Toll-like receptor 9 expression in mucoepidermoid salivary gland carcinoma may associate with good prognosis. J Oral Pathol Med. 2014;43:530-7 pubmed publisher
  • immunocytochemistry; human
Hamidi S, Schäfer Korting M, Weindl G. TLR2/1 and sphingosine 1-phosphate modulate inflammation, myofibroblast differentiation and cell migration in fibroblasts. Biochim Biophys Acta. 2014;1841:484-94 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Sathe A, Reddy K. TLR9 and RIG-I signaling in human endocervical epithelial cells modulates inflammatory responses of macrophages and dendritic cells in vitro. PLoS ONE. 2014;9:e83882 pubmed publisher
  • western blot; mouse
Chandel H, Pandey S, Shukla D, Lalsare K, Selvaraj S, Jha M, et al. Toll-like receptors and CD40 modulate each other's expression affecting Leishmania major infection. Clin Exp Immunol. 2014;176:283-90 pubmed publisher
Hiltunen N, Kemi N, V xe4 yrynen J, B xf6 hm J, Kauppila J, Huhta H, et al. Toll-like receptors 1-9 in small bowel neuroendocrine tumors-Clinical significance and prognosis. PLoS ONE. 2024;19:e0302813 pubmed publisher
Ramini D, Giuliani A, Kwiatkowska K, Guescini M, Storci G, Mens xe0 E, et al. Replicative senescence and high glucose induce the accrual of self-derived cytosolic nucleic acids in human endothelial cells. Cell Death Discov. 2024;10:184 pubmed publisher
Oh T, Kang G, Jo H, Park H, Lee Y, Ahn G. DNA-dependent protein kinase regulates cytosolic double-stranded DNA secretion from irradiated macrophages to increase radiosensitivity of tumors. Radiother Oncol. 2024;193:110111 pubmed publisher
Ni H, Wang Y, Yao K, Wang L, HUANG J, Xiao Y, et al. Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice. Nat Commun. 2024;15:1 pubmed publisher
Tripathi A, Bartosh A, Whitehead C, Pillai A. Activation of cell-free mtDNA-TLR9 signaling mediates chronic stress-induced social behavior deficits. Mol Psychiatry. 2023;28:3806-3815 pubmed publisher
Spurgeon B, Frelinger A. Platelet Phenotyping by Full Spectrum Flow Cytometry. Curr Protoc. 2023;3:e687 pubmed publisher
Meng Y, Ma J, Yao C, Ye Z, Ding H, Liu C, et al. The NCF1 variant p.R90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells. J Clin Invest. 2022;132: pubmed publisher
Lam L, Dobkin J, Eckart K, Gereg I, DiSalvo A, Nolder A, et al. Bat Red Blood Cells Express Nucleic Acid-Sensing Receptors and Bind RNA and DNA. Immunohorizons. 2022;6:299-306 pubmed publisher
Yu J, Kim J, Nam K, Lee W, Rhee D. Pneumococcal Δpep27 Immunization Attenuates TLRs and NLRP3 Expression and Relieves Murine Ovalbumin-Induced Allergic Rhinitis. J Microbiol Biotechnol. 2022;32:709-717 pubmed publisher
Ma X, Rawnsley D, Kovacs A, Islam M, Murphy J, Zhao C, et al. TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis. JACC Basic Transl Sci. 2022;7:223-243 pubmed publisher
Li Z, Fu W, Chen X, Wang S, Deng R, Tang X, et al. Autophagy-based unconventional secretion of HMGB1 in glioblastoma promotes chemosensitivity to temozolomide through macrophage M1-like polarization. J Exp Clin Cancer Res. 2022;41:74 pubmed publisher
Branchi V, Esser L, Boden C, Jafari A, Henn J, Lingohr P, et al. A Combined TLR7/TLR9/GATA3 Score Can Predict Prognosis in Biliary Tract Cancer. Diagnostics (Basel). 2021;11: pubmed publisher
Khin P, Hong Y, Yeon M, Lee D, Lee J, Jun H. Dulaglutide improves muscle function by attenuating inflammation through OPA-1-TLR-9 signaling in aged mice. Aging (Albany NY). 2021;13:21962-21974 pubmed publisher
Ishizu T, Eichin D, Padzik A, Tuominen S, Grenman R, Salmi M, et al. Head and neck squamous cell carcinoma cell lines have an immunomodulatory effect on macrophages independent of hypoxia and toll-like receptor 9. BMC Cancer. 2021;21:990 pubmed publisher
Kuramoto K, Kim Y, Hong J, He C. The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding. Cell Rep. 2021;35:109184 pubmed publisher
Li F, Surolia R, Li H, Wang Z, Liu G, Kulkarni T, et al. Citrullinated vimentin mediates development and progression of lung fibrosis. Sci Transl Med. 2021;13: pubmed publisher
Niemczyk G, Fus L, Czarzasta K, Jesion A, Radziszewski P, Gornicka B, et al. Expression of Toll-Like Receptors in the Animal Model of Bladder Outlet Obstruction. Biomed Res Int. 2020;2020:6632359 pubmed publisher
Korimová A, Dubovy P. N-Formylated Peptide Induces Increased Expression of Both Formyl Peptide Receptor 2 (Fpr2) and Toll-Like Receptor 9 (TLR9) in Schwannoma Cells-An In Vitro Model for Early Inflammatory Profiling of Schwann Cells. Cells. 2020;9: pubmed publisher
Wang C, Chen C, Lin M, Su H, Ho M, Yeh J, et al. TLR9 Binding to Beclin 1 and Mitochondrial SIRT3 by a Sodium-Glucose Co-Transporter 2 Inhibitor Protects the Heart from Doxorubicin Toxicity. Biology (Basel). 2020;9: pubmed publisher
Richard Albert J, Au Yeung W, Toriyama K, Kobayashi H, Hirasawa R, Brind Amour J, et al. Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo. Nat Commun. 2020;11:5417 pubmed publisher
Natarajan S, Ranganathan M. Toll-like receptor (TLR) gene expression and immunostimulatory effect of CpG oligonucleotides in hormone receptor positive cell line T47D and triple negative breast cancer cell line MDA-MB-468. Immunopharmacol Immunotoxicol. 2020;42:408-415 pubmed publisher
Zhou B, Yan J, Guo L, Zhang B, Liu S, Yu M, et al. Hepatoma cell-intrinsic TLR9 activation induces immune escape through PD-L1 upregulation in hepatocellular carcinoma. Theranostics. 2020;10:6530-6543 pubmed publisher
Du X, Ge W, Jing R, Pan L. Necroptosis in pulmonary macrophages mediates lipopolysaccharide-induced lung inflammatory injury by activating ZBP-1. Int Immunopharmacol. 2019;77:105944 pubmed publisher
Kalantari E, Abolhasani M, Roudi R, Farajollahi M, Farhad S, Madjd Z, et al. Co-expression of TLR-9 and MMP-13 is associated with the degree of tumour differentiation in prostate cancer. Int J Exp Pathol. 2019;100:123-132 pubmed publisher
Takahara M, Nagato T, Nozaki Y, Kumai T, Katada A, Hayashi T, et al. A proliferation-inducing ligand (APRIL) induced hyper-production of IgA from tonsillar mononuclear cells in patients with IgA nephropathy. Cell Immunol. 2019;341:103925 pubmed publisher
Kapelouzou A, Kontogiannis C, Tsilimigras D, Georgiopoulos G, Kaklamanis L, Tsourelis L, et al. Differential expression patterns of Toll Like Receptors and Interleukin-37 between calcific aortic and mitral valve cusps in humans. Cytokine. 2019;116:150-160 pubmed publisher
Leppänen J, Helminen O, Huhta H, Kauppila J, Isohookana J, Haapasaari K, et al. Toll-like receptors 2, 4 and 9 and hypoxia markers HIF-1alpha and CAIX in pancreatic intraepithelial neoplasia. APMIS. 2018;126:852-863 pubmed publisher
Nie H, Mei Z, Wang R, Zhao B, Gao Y, Chen J, et al. Bushen recipe and its disassembled prescriptions inhibit inflammation of liver injury associated with Concanavalin A through Toll‑like receptor 3/9 signaling pathway. Mol Med Rep. 2018;18:1682-1691 pubmed publisher
Yang J, Snijders M, Haasnoot G, van Kooten C, Mallat M, de Fijter J, et al. Elevated intragraft expression of innate immunity and cell death-related markers is a risk factor for adverse graft outcome. Transpl Immunol. 2018;48:39-46 pubmed publisher
Chandler M, Keene K, Tuomela J, Forero Torres A, Desmond R, Vuopala K, et al. Lower frequency of TLR9 variant associated with protection from breast cancer among African Americans. PLoS ONE. 2017;12:e0183832 pubmed publisher
Sun Y, Xiao Q, Luo C, Zhao Y, Pu D, Zhao K, et al. High-glucose induces tau hyperphosphorylation through activation of TLR9-P38MAPK pathway. Exp Cell Res. 2017;359:312-318 pubmed publisher
Heftrig D, Sturm R, Oppermann E, Kontradowitz K, Jurida K, Schimunek L, et al. Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients. Mediators Inflamm. 2017;2017:2608349 pubmed publisher
Larsson O, Tengroth L, Xu Y, Uddman R, Kumlien Georén S, Cardell L. Substance P represents a novel first-line defense mechanism in the nose. J Allergy Clin Immunol. 2018;141:128-136.e3 pubmed publisher
Leppänen J, Helminen O, Huhta H, Kauppila J, Isohookana J, Haapasaari K, et al. High toll-like receptor (TLR) 9 expression is associated with better prognosis in surgically treated pancreatic cancer patients. Virchows Arch. 2017;470:401-410 pubmed publisher
Helminen O, Huhta H, Kauppila J, Lehenkari P, Saarnio J, Karttunen T. Localization of nucleic acid-sensing toll-like receptors in human and mouse pancreas. APMIS. 2017;125:85-92 pubmed publisher
Garrison C, Lastwika K, Zhang Y, Li C, Lampe P. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections with Obesity. J Proteome Res. 2017;16:274-287 pubmed publisher
Mu L, Wang Y, Wang Y, Zhang H, Shang D, Tan F, et al. Tumor Location and Survival Outcomes in Adult Patients with Supratentorial Glioblastoma by Levels of Toll-Like Receptor 9 Expression. World Neurosurg. 2017;97:279-283 pubmed publisher
Burgueño J, Barba A, Eyre E, Romero C, Neunlist M, Fernández E. TLR2 and TLR9 modulate enteric nervous system inflammatory responses to lipopolysaccharide. J Neuroinflammation. 2016;13:187 pubmed publisher
Meseure D, Vacher S, Drak Alsibai K, Trassard M, Nicolas A, Leclère R, et al. Biopathological Significance of TLR9 Expression in Cancer Cells and Tumor Microenvironment Across Invasive Breast Carcinomas Subtypes. Cancer Microenviron. 2016;9:107-118 pubmed publisher
Schnerch J, Prasse A, Vlachakis D, Schuchardt K, Pechkovsky D, Goldmann T, et al. Functional Toll-Like Receptor 9 Expression and CXCR3 Ligand Release in Pulmonary Sarcoidosis. Am J Respir Cell Mol Biol. 2016;55:749-757 pubmed
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed publisher
Siponen M, Bitu C, Al Samadi A, Nieminen P, Salo T. Cathepsin K expression is increased in oral lichen planus. J Oral Pathol Med. 2016;45:758-765 pubmed publisher
Moreira M, Costa Pereira C, Alves M, Marteleto B, Ribeiro V, Peruhype Magalhães V, et al. Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes. Vet Parasitol. 2016;220:33-45 pubmed publisher
Evangelista M, Castro S, Alves C, Dias A, Souza V, Reis L, et al. Early IFN-? production together with decreased expression of TLR3 and TLR9 characterizes EAE development conditional on the presence of myelin. Autoimmunity. 2016;49:258-67 pubmed publisher
Dillmann C, Ringel C, Ringleb J, Mora J, Olesch C, Fink A, et al. S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells. J Immunol. 2016;196:1579-90 pubmed publisher
Duhamel M, Rodet F, Murgoci A, Desjardins R, Gagnon H, Wisztorski M, et al. The proprotein convertase PC1/3 regulates TLR9 trafficking and the associated signaling pathways. Sci Rep. 2016;6:19360 pubmed publisher
Mishima Y, Ishihara S, Oka A, Fukuba N, Oshima N, Sonoyama H, et al. Decreased Frequency of Intestinal Regulatory CD5+ B Cells in Colonic Inflammation. PLoS ONE. 2016;11:e0146191 pubmed publisher
Zambirinis C, Levie E, Nguy S, Avanzi A, Barilla R, Xu Y, et al. TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. J Exp Med. 2015;212:2077-94 pubmed publisher
Jamin A, Dehoux L, Dossier C, Fila M, Heming N, Monteiro R, et al. Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome. Clin Exp Immunol. 2015;182:332-45 pubmed publisher
Karlsen M, Hansen T, Nordal H, Brun J, Jonsson R, Appel S. Expression of Toll-like receptor -7 and -9 in B cell subsets from patients with primary Sjögren's syndrome. PLoS ONE. 2015;10:e0120383 pubmed publisher
Yu S, Wong C, Szeto C, Li E, Cai Z, Tam L. Members of the receptor for advanced glycation end products axis as potential therapeutic targets in patients with lupus nephritis. Lupus. 2015;24:675-86 pubmed publisher
Tengroth L, Arebro J, Kumlien Geor n S, Winqvist O, Cardell L. Deprived TLR9 expression in apparently healthy nasal mucosa might trigger polyp-growth in chronic rhinosinusitis patients. PLoS ONE. 2014;9:e105618 pubmed publisher
Lopez M, Palmer B, Lawrence D. Naïve T cells, unconventional NK and NKT cells, and highly responsive monocyte-derived macrophages characterize human cord blood. Immunobiology. 2014;219:756-65 pubmed publisher
Guerrier T, Pochard P, Lahiri A, Youinou P, Pers J, Jamin C. TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response. J Autoimmun. 2014;51:23-9 pubmed publisher
Belmont L, Rabbe N, Antoine M, Cathelin D, Guignabert C, Kurie J, et al. Expression of TLR9 in tumor-infiltrating mononuclear cells enhances angiogenesis and is associated with a worse survival in lung cancer. Int J Cancer. 2014;134:765-77 pubmed publisher
Väisänen M, Jukkola Vuorinen A, Vuopala K, Selander K, Vaarala M. Expression of Toll-like receptor-9 is associated with poor progression-free survival in prostate cancer. Oncol Lett. 2013;5:1659-1663 pubmed
Figueiredo M, Amorim I, Pinto A, Barbosa V, Pinheiro L, Deoti B, et al. Expression of Toll-like receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leishmania infantum. BMC Immunol. 2013;14:22 pubmed publisher
Abdi J, Mutis T, Garssen J, Redegeld F. Characterization of the Toll-like receptor expression profile in human multiple myeloma cells. PLoS ONE. 2013;8:e60671 pubmed publisher
Chauhan S, Singh V, Rai R, Rai M, Rai G. Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation. J Clin Immunol. 2013;33:954-64 pubmed publisher
Schneberger D, Caldwell S, Kanthan R, Singh B. Expression of Toll-like receptor 9 in mouse and human lungs. J Anat. 2013;222:495-503 pubmed publisher
Hu F, Zhang L, Zheng J, Zhao L, Huang J, Shao W, et al. Spontaneous production of immunoglobulin M in human epithelial cancer cells. PLoS ONE. 2012;7:e51423 pubmed publisher
Harman A, Bye C, Nasr N, Sandgren K, Kim M, Mercier S, et al. Identification of lineage relationships and novel markers of blood and skin human dendritic cells. J Immunol. 2013;190:66-79 pubmed publisher
Kauppila J, Karttunen T, Saarnio J, Nyberg P, Salo T, Graves D, et al. Short DNA sequences and bacterial DNA induce esophageal, gastric, and colorectal cancer cell invasion. APMIS. 2013;121:511-22 pubmed publisher
Siponen M, Kauppila J, Soini Y, Salo T. TLR4 and TLR9 are induced in oral lichen planus. J Oral Pathol Med. 2012;41:741-7 pubmed publisher
Souza Fonseca Guimaraes F, Parlato M, Fitting C, Cavaillon J, Adib Conquy M. NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis. J Immunol. 2012;188:5850-8 pubmed publisher
Silver A, Arjona A, Walker W, Fikrig E. The circadian clock controls toll-like receptor 9-mediated innate and adaptive immunity. Immunity. 2012;36:251-61 pubmed publisher
O Hara J, Feener T, Fischer C, Buret A. Campylobacter jejuni disrupts protective Toll-like receptor 9 signaling in colonic epithelial cells and increases the severity of dextran sulfate sodium-induced colitis in mice. Infect Immun. 2012;80:1563-71 pubmed publisher
Zuo D, Yu X, Guo C, Yi H, Chen X, Conrad D, et al. Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity. FASEB J. 2012;26:1493-505 pubmed publisher
Kauppila J, Takala H, Selander K, Lehenkari P, Saarnio J, Karttunen T. Increased Toll-like receptor 9 expression indicates adverse prognosis in oesophageal adenocarcinoma. Histopathology. 2011;59:643-9 pubmed publisher
Ronkainen H, Hirvikoski P, Kauppila S, Vuopala K, Paavonen T, Selander K, et al. Absent Toll-like receptor-9 expression predicts poor prognosis in renal cell carcinoma. J Exp Clin Cancer Res. 2011;30:84 pubmed publisher
Luckhardt T, Coomes S, Trujillo G, Stoolman J, Vannella K, Bhan U, et al. TLR9-induced interferon ? is associated with protection from gammaherpesvirus-induced exacerbation of lung fibrosis. Fibrogenesis Tissue Repair. 2011;4:18 pubmed publisher
Lundeen J, Sutherland B, Patel A, Stewart C, Bamber C. Direct measurement of the quantum wavefunction. Nature. 2011;474:188-91 pubmed publisher
Karim R, Meyers C, Backendorf C, Ludigs K, Offringa R, van Ommen G, et al. Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes. PLoS ONE. 2011;6:e17848 pubmed publisher
Dasgupta G, Chentoufi A, You S, Falatoonzadeh P, Urbano L, Akhtarmalik A, et al. Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci. 2011;52:3321-33 pubmed publisher
van Gent M, Griffin B, Berkhoff E, van Leeuwen D, Boer I, Buisson M, et al. EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection. J Immunol. 2011;186:1694-702 pubmed publisher
Myles A, Aggarwal A. Expression of Toll-like receptors 2 and 4 is increased in peripheral blood and synovial fluid monocytes of patients with enthesitis-related arthritis subtype of juvenile idiopathic arthritis. Rheumatology (Oxford). 2011;50:481-8 pubmed publisher
Baumann C, Aspalter I, Sharif O, Pichlmair A, Blüml S, Grebien F, et al. CD14 is a coreceptor of Toll-like receptors 7 and 9. J Exp Med. 2010;207:2689-701 pubmed publisher
Schneberger D, Lewis D, Caldwell S, Singh B. Expression of toll-like receptor 9 in lungs of pigs, dogs and cattle. Int J Exp Pathol. 2011;92:1-7 pubmed publisher
Sethi R, Brar R, Singh O, Singh B. Immunolocalization of pulmonary intravascular macrophages, TLR4, TLR9 and IL-8 in normal and Pasteurella multocida-infected lungs of water buffalo (Bubalus bubalis). J Comp Pathol. 2011;144:135-44 pubmed publisher
Wang C, Cao S, Yan Y, Ying Q, Jiang T, Xu K, et al. TLR9 expression in glioma tissues correlated to glioma progression and the prognosis of GBM patients. BMC Cancer. 2010;10:415 pubmed publisher
Booth J, Arsenault R, Napper S, Griebel P, Potter A, Babiuk L, et al. TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides. J Innate Immun. 2010;2:483-94 pubmed publisher
Keestra A, de Zoete M, Bouwman L, van Putten J. Chicken TLR21 is an innate CpG DNA receptor distinct from mammalian TLR9. J Immunol. 2010;185:460-7 pubmed publisher
Jukkola Vuorinen A, Rahko E, Vuopala K, Desmond R, Lehenkari P, Harris K, et al. Toll-like receptor-9 expression is inversely correlated with estrogen receptor status in breast cancer. J Innate Immun. 2009;1:59-68 pubmed publisher
Machida H, Ito S, Hirose T, Takeshita F, Oshiro H, Nakamura T, et al. Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis. Nephrol Dial Transplant. 2010;25:2530-537 pubmed publisher
Kim Y, Park J, Brand D, Fitzpatrick E, Yi A. Protein kinase D1 is essential for the proinflammatory response induced by hypersensitivity pneumonitis-causing thermophilic actinomycetes Saccharopolyspora rectivirgula. J Immunol. 2010;184:3145-56 pubmed publisher
Panda A, Qian F, Mohanty S, van Duin D, Newman F, Zhang L, et al. Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol. 2010;184:2518-27 pubmed publisher
Chentoufi A, Dasgupta G, Nesburn A, Bettahi I, Binder N, Choudhury Z, et al. Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization. Clin Vaccine Immunol. 2010;17:342-53 pubmed publisher
Väisänen M, Väisänen T, Jukkola Vuorinen A, Vuopala K, Desmond R, Selander K, et al. Expression of toll-like receptor-9 is increased in poorly differentiated prostate tumors. Prostate. 2010;70:817-24 pubmed publisher
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. 2010;129:363-74 pubmed publisher
Schneberger D, Caldwell S, Suri S, Singh B. Expression of toll-like receptor 9 in horse lungs. Anat Rec (Hoboken). 2009;292:1068-77 pubmed publisher
Yang X, Fullerton D, Su X, Ao L, Cleveland J, Meng X. Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2. J Am Coll Cardiol. 2009;53:491-500 pubmed publisher
Zhou M, McFarland Mancini M, Funk H, Husseinzadeh N, Mounajjed T, Drew A. Toll-like receptor expression in normal ovary and ovarian tumors. Cancer Immunol Immunother. 2009;58:1375-85 pubmed publisher
Donaghy H, Bosnjak L, Harman A, Marsden V, Tyring S, Meng T, et al. Role for plasmacytoid dendritic cells in the immune control of recurrent human herpes simplex virus infection. J Virol. 2009;83:1952-61 pubmed publisher
Palladino M, Savarese M, Chapman J, Dughi M, Plaska D. Localization of Toll-like receptors on epididymal epithelial cells and spermatozoa. Am J Reprod Immunol. 2008;60:541-55 pubmed publisher
Sacre S, Lo A, Gregory B, Simmonds R, Williams L, Feldmann M, et al. Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures. J Immunol. 2008;181:8002-9 pubmed
Ilvesaro J, Merrell M, Li L, Wakchoure S, Graves D, Brooks S, et al. Toll-like receptor 9 mediates CpG oligonucleotide-induced cellular invasion. Mol Cancer Res. 2008;6:1534-43 pubmed publisher
Meneghin A, Choi E, Evanoff H, Kunkel S, Martinez F, Flaherty K, et al. TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation. Histochem Cell Biol. 2008;130:979-92 pubmed publisher
Cohen P, Koski G, Czerniecki B, Bunting K, Fu X, Wang Z, et al. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 2008;112:1832-43 pubmed publisher
Selleri S, Palazzo M, Deola S, Wang E, Balsari A, Marincola F, et al. Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS. Int Immunol. 2008;20:961-70 pubmed publisher
Ju X, Zenke M, Hart D, Clark G. CD300a/c regulate type I interferon and TNF-alpha secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. Blood. 2008;112:1184-94 pubmed publisher
Hammadi A, Billard C, Faussat A, Kolb J. Stimulation of iNOS expression and apoptosis resistance in B-cell chronic lymphocytic leukemia (B-CLL) cells through engagement of Toll-like receptor 7 (TLR-7) and NF-kappaB activation. Nitric Oxide. 2008;19:138-45 pubmed publisher
Zhang Y, Davis E, Blecha F, Wilkerson M. Molecular cloning and characterization of equine Toll-like receptor 9. Vet Immunol Immunopathol. 2008;124:209-19 pubmed publisher
Cognasse F, Hamzeh Cognasse H, Lafarge S, Chavarin P, Pozzetto B, Richard Y, et al. Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. Immunology. 2008;125:430-7 pubmed publisher
Burgener I, Jungi T. Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol. 2008;124:184-91 pubmed publisher
Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, et al. Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway. J Immunol. 2008;180:4067-74 pubmed
Pegu A, Qin S, Fallert Junecko B, Nisato R, Pepper M, Reinhart T. Human lymphatic endothelial cells express multiple functional TLRs. J Immunol. 2008;180:3399-405 pubmed
Meng Y, Kujas M, Marie Y, Paris S, Thillet J, Delattre J, et al. Expression of TLR9 within human glioblastoma. J Neurooncol. 2008;88:19-25 pubmed publisher
Nakano S, Morimoto S, Suzuki J, Nozawa K, Amano H, Tokano Y, et al. Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus. Rheumatology (Oxford). 2008;47:145-9 pubmed
Kundu S, Lee C, Billips B, Habermacher G, Zhang Q, Liu V, et al. The toll-like receptor pathway: a novel mechanism of infection-induced carcinogenesis of prostate epithelial cells. Prostate. 2008;68:223-9 pubmed
Gonzalez J, Xu H, Ofori E, Elovitz M. Toll-like receptors in the uterus, cervix, and placenta: is pregnancy an immunosuppressed state?. Am J Obstet Gynecol. 2007;197:296.e1-6 pubmed
Tran N, Koch A, Berkels R, Boehm O, Zacharowski P, Baumgarten G, et al. Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation. J Clin Endocrinol Metab. 2007;92:2773-83 pubmed
Kindrachuk J, Potter J, Brownlie R, Ficzycz A, Griebel P, Mookherjee N, et al. Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9. J Biol Chem. 2007;282:13944-53 pubmed
Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed
Ewaschuk J, Backer J, Churchill T, Obermeier F, Krause D, Madsen K. Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA. Infect Immun. 2007;75:2572-9 pubmed
Palladino M, Johnson T, Gupta R, Chapman J, Ojha P. Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract. Biol Reprod. 2007;76:958-64 pubmed
Lee J, Mo J, Katakura K, Alkalay I, Rucker A, Liu Y, et al. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol. 2006;8:1327-36 pubmed
Dhara A, Saini M, Das D, Swarup D, Sharma B, Kumar S, et al. Molecular characterization of coding sequences and analysis of Toll-like receptor 3 mRNA expression in water buffalo (Bubalus bubalis) and nilgai (Boselaphus tragocamelus). Immunogenetics. 2007;59:69-76 pubmed publisher
Niessner A, Sato K, Chaikof E, Colmegna I, Goronzy J, Weyand C. Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation. 2006;114:2482-9 pubmed
Huggins J, Pellegrin T, Felgar R, Wei C, Brown M, Zheng B, et al. CpG DNA activation and plasma-cell differentiation of CD27- naive human B cells. Blood. 2007;109:1611-9 pubmed
Wang H, Nicholas M, Conway K, Sen P, Diz R, Tisch R, et al. EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity. J Immunol. 2006;177:2793-802 pubmed
Mansson A, Adner M, Cardell L. Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Respir Res. 2006;7:36 pubmed
Gottenberg J, Cagnard N, Lucchesi C, Letourneur F, Mistou S, Lazure T, et al. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. Proc Natl Acad Sci U S A. 2006;103:2770-5 pubmed
Martin Armas M, Simon Santamaria J, Pettersen I, Moens U, Smedsrød B, Sveinbjørnsson B. Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides. J Hepatol. 2006;44:939-46 pubmed
Lee J, Wu C, Lee K, Chuang T, Katakura K, Liu Y, et al. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci U S A. 2006;103:1828-33 pubmed
Damiano V, Caputo R, Bianco R, D Armiento F, Leonardi A, De Placido S, et al. Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors. Clin Cancer Res. 2006;12:577-83 pubmed
Tabeta K, Hoebe K, Janssen E, Du X, Georgel P, Crozat K, et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol. 2006;7:156-64 pubmed
Srivastava M, Srivastava B. Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line. Leuk Res. 2005;29:813-20 pubmed
Miller L, Sørensen O, Liu P, Jalian H, Eshtiaghpour D, Behmanesh B, et al. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. J Immunol. 2005;174:6137-43 pubmed
Abel K, Wang Y, Fritts L, Sanchez E, Chung E, Fitzgerald Bocarsly P, et al. Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoi. Clin Diagn Lab Immunol. 2005;12:606-21 pubmed
Cognasse F, Hamzeh H, Chavarin P, Acquart S, Genin C, Garraud O. Evidence of Toll-like receptor molecules on human platelets. Immunol Cell Biol. 2005;83:196-8 pubmed
Greene C, Carroll T, Smith S, Taggart C, Devaney J, Griffin S, et al. TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells. J Immunol. 2005;174:1638-46 pubmed
Droemann D, Albrecht D, Gerdes J, Ulmer A, Branscheid D, Vollmer E, et al. Human lung cancer cells express functionally active Toll-like receptor 9. Respir Res. 2005;6:1 pubmed
Zhong F, Cao W, Chan E, Tay P, Cahya F, Zhang H, et al. Deviation from major codons in the Toll-like receptor genes is associated with low Toll-like receptor expression. Immunology. 2005;114:83-93 pubmed
Lee H, Dunzendorfer S, Tobias P. Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation. J Biol Chem. 2004;279:10564-74 pubmed
Gantner F, Hermann P, Nakashima K, Matsukawa S, Sakai K, Bacon K. CD40-dependent and -independent activation of human tonsil B cells by CpG oligodeoxynucleotides. Eur J Immunol. 2003;33:1576-85 pubmed
product information
master code :
NBP2-24729
SKU :
NBP2-24729
product name :
TLR9 Antibody (26C593.2) - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TLR9 Antibody (26C593.2) - BSA Free from Novus is a mouse monoclonal antibody to TLR9. This antibody reacts with canine,equine,human,monkey,mouse,porcine,primate,rat. The TLR9 Antibody (26C593.2) - BSA Free has been validated for the following applications: Western Blot,Cytometric Bead Assay Standard,Flow Cytometry Control,IF/IHC,ELISA,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,In vitro assay,Knockdown Validated,Block/Neutralize,Functional Assay,Immunocytochemistry/ Immunofluorescence,Functional,Dot Blot,Flow (Intracellular),Simple Western,CyTOF-ready.
target :
TLR9
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
26C593.2
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This antibody was developed against KLH-conjugated synthetic peptide corresponding to amino acids 268-300 of human TLR9 isoform A (Genbank accession no. AAF78037).
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Canine,Equine,Human,Monkey,Mouse,Porcine,Primate,Rat
gene symbol :
TLR9
Antibody validation :
Knockout/Knockdown
accessionNumbers :
Q9NR96
applications :
Western Blot,Cytometric Bead Assay Standard,Flow Cytometry Control,IF/IHC,ELISA,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,In vitro assay,Knockdown Validated,Block/Neutralize,Functional Assay,Immunocytochemistry/ Immunofluorescence,Functional,Dot Blot,Flow (Intracellular),Simple Western,CyTOF-ready
USD :
469 USD
alt names :
CD289, CD289 antigen, toll-like receptor 9
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.