| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1c
- immunohistochemistry; mouse; 1:100; loading ...; fig s5a
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| Herbstein F, Sapochnik M, Attorresi A, Pollak C, Senin S, Gonilski Pacin D, et al. The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway. Aging Cell. 2024;23:e14258 pubmed publisher |
| Pham A, Oliveira A, Albanna M, Alvarez Castanon J, Dupee Z, Patel D, et al. Non-Interferon-Dependent Role of STING Signaling in Pulmonary Hypertension. Arterioscler Thromb Vasc Biol. 2024;44:124-142 pubmed publisher |
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| Gupta U, Ghosh S, Wallace C, Shang P, Xin Y, Nair A, et al. Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD. Autophagy. 2023;19:92-111 pubmed publisher |
| Gong L, Yang X, Yang J, Wu S, Chen Y, Zhang J, et al. Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice. Front Pharmacol. 2022;13:1020670 pubmed publisher |
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| Jiang G, Yang X, Zhou H, Long J, Liu B, Zhang L, et al. cGAS knockdown promotes microglial M2 polarization to alleviate neuroinflammation by inhibiting cGAS-STING signaling pathway in cerebral ischemic stroke. Brain Res Bull. 2021;171:183-195 pubmed publisher |
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| Yu H, Kim Y, Cho M. Cytoplasm-localized SIRT1 downregulation attenuates apoptosis and cell cycle arrest in cisplatin-resistant lung cancer A549 cells. J Cancer. 2020;11:4495-4509 pubmed publisher |
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| Kim Y, Kim J, Gu S, Jo S, Kim S, Young Kim S, et al. Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis. Sci Rep. 2020;10:4570 pubmed publisher |
| Qu H, Li L, Wang T, Seckin T, Segars J, Shih I. Epithelial Cells in Endometriosis and Adenomyosis Upregulate STING Expression. Reprod Sci. 2020;27:1276-1284 pubmed publisher |
| Wang L, Chiou J, Lee Y, Huang C, Shi Y, Chang L. SIRT3, PP2A and TTP protein stability in the presence of TNF-α on vincristine-induced apoptosis of leukaemia cells. J Cell Mol Med. 2020;24:2552-2565 pubmed publisher |
| Li L, Chen B, Zhu R, Li R, Tian Y, Liu C, et al. Fructus Ligustri Lucidi preserves bone quality through the regulation of gut microbiota diversity, oxidative stress, TMAO and Sirt6 levels in aging mice. Aging (Albany NY). 2019;11:9348-9368 pubmed publisher |
| Chen Y, Wu T, Ho C, Yeh T, Sun G, Kung Y, et al. Dapagliflozin Prevents NOX- and SGLT2-Dependent Oxidative Stress in Lens Cells Exposed to Fructose-Induced Diabetes Mellitus. Int J Mol Sci. 2019;20: pubmed publisher |
| Rojas Morales P, Tapia E, León Contreras J, González Reyes S, Jiménez Osorio A, Trujillo J, et al. Mechanisms of Fasting-Mediated Protection against Renal Injury and Fibrosis Development after Ischemic Acute Kidney Injury. Biomolecules. 2019;9: pubmed publisher |
| Yang H, Lee W, Kong S, Kim C, Kim J, Chang S, et al. STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade. J Clin Invest. 2019;129:4350-4364 pubmed publisher |
| Wegner A, Campos N, Robbins M, Haddad A, Cunningham H, Yik J, et al. Acute Changes in NADPH Oxidase 4 in Early Post-Traumatic Osteoarthritis. J Orthop Res. 2019;37:2429-2436 pubmed publisher |
| Ikeda S, Matsushima S, Okabe K, Ikeda M, Ishikita A, Tadokoro T, et al. Blockade of L-type Ca2+ channel attenuates doxorubicin-induced cardiomyopathy via suppression of CaMKII-NF-κB pathway. Sci Rep. 2019;9:9850 pubmed publisher |
| Chen Z, Tao S, Li X, Zeng X, Zhang M, Yao Q. Anagliptin protects neuronal cells against endogenous amyloid β (Aβ)-induced cytotoxicity and apoptosis. Artif Cells Nanomed Biotechnol. 2019;47:2213-2220 pubmed publisher |
| Buck T, Hack C, Berg D, Berg U, Kunz L, Mayerhofer A. The NADPH oxidase 4 is a major source of hydrogen peroxide in human granulosa-lutein and granulosa tumor cells. Sci Rep. 2019;9:3585 pubmed publisher |
| Bitar M, Nader J, Al Ali W, Al Madhoun A, Arefanian H, Al Mulla F. Hydrogen Sulfide Donor NaHS Improves Metabolism and Reduces Muscle Atrophy in Type 2 Diabetes: Implication for Understanding Sarcopenic Pathophysiology. Oxid Med Cell Longev. 2018;2018:6825452 pubmed publisher |
| Tang P, Dang H, Huang J, Xu T, Yuan P, Hu J, et al. NADPH oxidase NOX4 is a glycolytic regulator through mROS-HIF1α axis in thyroid carcinomas. Sci Rep. 2018;8:15897 pubmed publisher |
| Lanza Jacoby S, Cheng G. 3,3'-Diindolylmethane enhances apoptosis in docetaxel-treated breast cancer cells by generation of reactive oxygen species. Pharm Biol. 2018;56:407-414 pubmed publisher |
| Liu R, Yan X. Sulforaphane protects rabbit corneas against oxidative stress injury in keratoconus through activation of the Nrf-2/HO-1 antioxidant pathway. Int J Mol Med. 2018;42:2315-2328 pubmed publisher |
| Lindquist R, Bayat Sarmadi J, Leben R, Niesner R, Hauser A. NAD(P)H Oxidase Activity in the Small Intestine Is Predominantly Found in Enterocytes, Not Professional Phagocytes. Int J Mol Sci. 2018;19: pubmed publisher |
| Seo G, Hyun C, Koh D, Park S, Lim Y, Kim Y, et al. A Novel Synthetic Material, BMM, Accelerates Wound Repair by Stimulating Re-Epithelialization and Fibroblast Activation. Int J Mol Sci. 2018;19: pubmed publisher |
| Dai Y, Zhang H, Zhang J, Yan M. Isoquercetin attenuates oxidative stress and neuronal apoptosis after ischemia/reperfusion injury via Nrf2-mediated inhibition of the NOX4/ROS/NF-κB pathway. Chem Biol Interact. 2018;284:32-40 pubmed publisher |
| Moloney J, Jayavelu A, Stanicka J, Roche S, O Brien R, Scholl S, et al. Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML. Oncotarget. 2017;8:105440-105457 pubmed publisher |
| Shanmugasundaram K, Nayak B, Friedrichs W, Kaushik D, Rodriguez R, Block K. NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance. Nat Commun. 2017;8:997 pubmed publisher |
| Tsubouchi K, Araya J, Minagawa S, Hara H, Ichikawa A, Saito N, et al. Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4. Autophagy. 2017;13:1420-1434 pubmed publisher |
| Wang L, Ma R, Guo Y, Sun J, Liu H, Zhu R, et al. Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway. Front Pharmacol. 2017;8:266 pubmed publisher |
| Kim Y, Kim S, Tatsunami R, Yamamura H, Fukai T, Ushio Fukai M. ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis. Am J Physiol Cell Physiol. 2017;312:C749-C764 pubmed publisher |
| Bhattacharya S, Srinivasan K, Abdisalaam S, Su F, Raj P, Dozmorov I, et al. RAD51 interconnects between DNA replication, DNA repair and immunity. Nucleic Acids Res. 2017;45:4590-4605 pubmed publisher |
| Sigala F, Efentakis P, Karageorgiadi D, Filis K, Zampas P, Iliodromitis E, et al. Reciprocal regulation of eNOS, H2S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin. Redox Biol. 2017;12:70-81 pubmed publisher |
| Dickson B, Gatie M, Spice D, Kelly G. NOX1 and NOX4 are required for the differentiation of mouse F9 cells into extraembryonic endoderm. PLoS ONE. 2017;12:e0170812 pubmed publisher |
| Sweetwyne M, Pippin J, Eng D, Hudkins K, Chiao Y, Campbell M, et al. The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age. Kidney Int. 2017;91:1126-1145 pubmed publisher |
| Chen L, Zhao M, Li J, Wang Y, Bao Q, Wu S, et al. Critical role of X-box binding protein 1 in NADPH oxidase 4-triggered cardiac hypertrophy is mediated by receptor interacting protein kinase 1. Cell Cycle. 2017;16:348-359 pubmed publisher |
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| Reinert L, Lopušná K, Winther H, Sun C, Thomsen M, Nandakumar R, et al. Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. Nat Commun. 2016;7:13348 pubmed publisher |
| Liu X, Hao B, Ma A, He J, Liu X, Chen J. The Expression of NOX4 in Smooth Muscles of Small Airway Correlates with the Disease Severity of COPD. Biomed Res Int. 2016;2016:2891810 pubmed |
| Sato N, Takasaka N, Yoshida M, Tsubouchi K, Minagawa S, Araya J, et al. Metformin attenuates lung fibrosis development via NOX4 suppression. Respir Res. 2016;17:107 pubmed publisher |
| Dosoki H, Stegemann A, Taha M, Schnittler H, Luger T, Schröder K, et al. Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis. Exp Dermatol. 2017;26:73-81 pubmed publisher |
| Maraldi T, Resca E, Nicoli A, Beretti F, Zavatti M, Capodanno F, et al. NADPH oxidase-4 and MATER expressions in granulosa cells: Relationships with ovarian aging. Life Sci. 2016;162:108-14 pubmed publisher |
| Min H, Cha J, Kim K, Kim J, Ghee J, Kim H, et al. Renoprotective Effects of a Highly Selective A3 Adenosine Receptor Antagonist in a Mouse Model of Adriamycin-induced Nephropathy. J Korean Med Sci. 2016;31:1403-12 pubmed publisher |
| Avin K, Chen N, Organ J, Zarse C, O Neill K, Conway R, et al. Skeletal Muscle Regeneration and Oxidative Stress Are Altered in Chronic Kidney Disease. PLoS ONE. 2016;11:e0159411 pubmed publisher |
| Dushpanova A, Agostini S, Ciofini E, Cabiati M, Casieri V, Matteucci M, et al. Gene silencing of endothelial von Willebrand Factor attenuates angiotensin II-induced endothelin-1 expression in porcine aortic endothelial cells. Sci Rep. 2016;6:30048 pubmed publisher |
| Dalal S, Zha Q, Singh M, Singh K. Osteopontin-stimulated apoptosis in cardiac myocytes involves oxidative stress and mitochondrial death pathway: role of a pro-apoptotic protein BIK. Mol Cell Biochem. 2016;418:1-11 pubmed publisher |
| Tyurin Kuzmin P, Zhdanovskaya N, Sukhova A, Sagaradze G, Albert E, Ageeva L, et al. Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF. PLoS ONE. 2016;11:e0154157 pubmed publisher |
| Li T, Cheng H, Yuan H, Xu Q, Shu C, Zhang Y, et al. Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response. Sci Rep. 2016;6:19049 pubmed publisher |
| Shi Y, Sun X, Sun Y, Hou L, Yao M, Lian K, et al. Elevation of cortical C26:0 due to the decline of peroxisomal β-oxidation potentiates amyloid β generation and spatial memory deficits via oxidative stress in diabetic rats. Neuroscience. 2016;315:125-35 pubmed publisher |
| Austin S, Santhanam A, d Uscio L, Katusic Z. Regional Heterogeneity of Cerebral Microvessels and Brain Susceptibility to Oxidative Stress. PLoS ONE. 2015;10:e0144062 pubmed publisher |
| Cheng G, Lanza Jacoby S. Metformin decreases growth of pancreatic cancer cells by decreasing reactive oxygen species: Role of NOX4. Biochem Biophys Res Commun. 2015;465:41-6 pubmed publisher |
| Youn J, Zhou J, Cai H. Bone Morphogenic Protein 4 Mediates NOX1-Dependent eNOS Uncoupling, Endothelial Dysfunction, and COX2 Induction in Type 2 Diabetes Mellitus. Mol Endocrinol. 2015;29:1123-33 pubmed publisher |
| Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. J Immunol. 2015;194:1819-31 pubmed publisher |
| Yu C, Luo X, Duquette N, Thorin Trescases N, Thorin E. Knockdown of angiopoietin like-2 protects against angiotensin II-induced cerebral endothelial dysfunction in mice. Am J Physiol Heart Circ Physiol. 2015;308:H386-97 pubmed publisher |
| Sanders Y, Liu H, Liu G, Thannickal V. Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescence. Free Radic Biol Med. 2015;79:197-205 pubmed publisher |
| Milara J, Peiró T, Serrano A, Artigues E, Aparicio J, Tenor H, et al. Simvastatin Increases the Ability of Roflumilast N-oxide to Inhibit Cigarette Smoke-Induced Epithelial to Mesenchymal Transition in Well-differentiated Human Bronchial Epithelial Cells in vitro. COPD. 2015;12:320-31 pubmed publisher |
