product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
RIPK3/RIP3 Antibody - BSA Free
catalog :
NBP2-24588
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay
more info or order :
citations: 11
Reference
Mall R, Bynigeri R, Karki R, Malireddi R, Sharma B, Kanneganti T. Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology. NAR Cancer. 2022;4:zcac033 pubmed publisher
Kalus P, De Munck J, Vanbellingen S, Carreer L, Laeremans T, Broos K, et al. Oncolytic Herpes Simplex Virus Type 1 Induces Immunogenic Cell Death Resulting in Maturation of BDCA-1+ Myeloid Dendritic Cells. Int J Mol Sci. 2022;23: pubmed publisher
Feoktistova M, Makarov R, Yazdi A, Panayotova Dimitrova D. RIPK1 and TRADD Regulate TNF-Induced Signaling and Ripoptosome Formation. Int J Mol Sci. 2021;22: pubmed publisher
Malireddi R, Karki R, Sundaram B, Kancharana B, Lee S, Samir P, et al. Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth. Immunohorizons. 2021;5:568-580 pubmed publisher
Damgaard R, Jolin H, Allison M, Davies S, Titheradge H, McKenzie A, et al. OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer. Cell Death Differ. 2020;27:1457-1474 pubmed publisher
Shrestha A, Mehdizadeh Gohari I, McClane B. RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin. MBio. 2019;10: pubmed publisher
Zinngrebe J, Schlichtig F, Kraus J, Meyer M, Boldrin E, Kestler H, et al. Biomarker profile for prediction of response to SMAC mimetic monotherapy in pediatric precursor B-cell acute lymphoblastic leukemia. Int J Cancer. 2020;146:3219-3231 pubmed publisher
Goulielmaki M, Assimomytis N, Rožanc J, Taki E, Christodoulou I, Alexopoulos L, et al. DPS-2: A Novel Dual MEK/ERK and PI3K/AKT Pathway Inhibitor with Powerful Ex Vivo and In Vivo Anticancer Properties. Transl Oncol. 2019;12:932-950 pubmed publisher
Podder B, Guttà C, Rožanc J, Gerlach E, Feoktistova M, Panayotova Dimitrova D, et al. TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma. Cell Death Differ. 2019;: pubmed publisher
Yang L, Joseph S, Sun T, Hoffmann J, Thevissen S, Offermanns S, et al. TAK1 regulates endothelial cell necroptosis and tumor metastasis. Cell Death Differ. 2019;: pubmed publisher
Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand A, Robertson D, et al. RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol Cell. 2019;73:413-428.e7 pubmed publisher
product information
master code :
NBP2-24588
SKU :
NBP2-24588
product name :
RIPK3/RIP3 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The RIPK3/RIP3 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to RIPK3/RIP3. This antibody reacts with human,mouse,mouse (negative),primate. The RIPK3/RIP3 Antibody - BSA Free has been validated for the following applications: Western Blot,Proximity Ligation Assay,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
RIPK3/RIP3
category :
Primary Antibodies
buffer :
0.1 ml PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
RIPK3/RIP3 Antibody was made to a synthetic peptide (QEGPKDPEAWSRPQ) corresponding to amino acids 497-518 of human RIPK3/RIP3 was used as immunogen for this antibody (isoform CRA_a, 518 amino acids, NP_006862.2). This also corresponds to amino acids 298-311 of isoform CRA_b (GenBank: EAW66022.1).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Mouse (Negative),Primate
theoretical molecular weight :
56.7 kDa
gene symbol :
RIPK3
Antibody validation :
Biological Validation
accessionNumbers :
Q9Y572
applications :
Western Blot,Proximity Ligation Assay,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
EC 2.7.11.1, Receptor Interacting Serine/Threonine Kinase 3, Receptor-interacting protein 3, receptor-interacting serine/threonine-protein kinase 3, receptor-interacting serine-threonine kinase 3, RIP3, RIP-3, RIP-like protein kinase 3
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.