product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Aiolos/IKZF3 Antibody - BSA Free
catalog :
NBP2-24495
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
Novus Biologicals product webpage
citations: 12
Reference
Zou Y, Liu B, Li L, Yin Q, Tang J, Jing Z, et al. IKZF3 deficiency potentiates chimeric antigen receptor T cells targeting solid tumors. Cancer Lett. 2022;524:121-130 pubmed publisher
Chen H, Liu J, Kaniskan H, Wei W, Jin J. Folate-Guided Protein Degradation by Immunomodulatory Imide Drug-Based Molecular Glues and Proteolysis Targeting Chimeras. J Med Chem. 2021;64:12273-12285 pubmed publisher
Barankiewicz J, Szumera Ciećkiewicz A, Salomon Perzyński A, Wieszczy P, Malenda A, Garbicz F, et al. The CRBN, CUL4A and DDB1 Expression Predicts the Response to Immunomodulatory Drugs and Survival of Multiple Myeloma Patients. J Clin Med. 2021;10: pubmed publisher
Walker Z, Idler B, Davis L, Stevens B, VanWyngarden M, Ohlstrom D, et al. Exploiting Protein Translation Dependence in Multiple Myeloma with Omacetaxine-Based Therapy. Clin Cancer Res. 2021;27:819-830 pubmed publisher
Wang Z, Zhou G, Risu N, Fu J, Zou Y, Tang J, et al. Lenalidomide Enhances CAR-T Cell Activity Against Solid Tumor Cells. Cell Transplant. 2020;29:963689720920825 pubmed publisher
Liu J, Chen H, Ma L, He Z, Wang D, Liu Y, et al. Light-induced control of protein destruction by opto-PROTAC. Sci Adv. 2020;6:eaay5154 pubmed publisher
Kim E, ten Hacken E, Sivina M, Clarke A, Thompson P, Jain N, et al. The BET inhibitor GS-5829 targets chronic lymphocytic leukemia cells and their supportive microenvironment. Leukemia. 2020;34:1588-1598 pubmed publisher
Zhu Y, Shi C, Bruins L, Wang X, Riggs D, Porter B, et al. Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4. Blood Cancer J. 2019;9:19 pubmed publisher
Costa F, Vescovini R, Bolzoni M, Marchica V, Storti P, Toscani D, et al. Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties. Oncotarget. 2017;8:53053-53067 pubmed publisher
Uehara T, Minoshima Y, Sagane K, Sugi N, Mitsuhashi K, Yamamoto N, et al. Selective degradation of splicing factor CAPERα by anticancer sulfonamides. Nat Chem Biol. 2017;13:675-680 pubmed publisher
Nguyen T, Li J, Lu C, Mamrosh J, Lu G, Cathers B, et al. p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates. Proc Natl Acad Sci U S A. 2017;114:3565-3571 pubmed publisher
Gao S, Geng C, Song T, Lin X, Liu J, Cai Z, et al. Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase. J Biol Chem. 2017;292:3683-3691 pubmed publisher
product information
master code :
NBP2-24495
SKU :
NBP2-24495
product name :
Aiolos/IKZF3 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The Aiolos/IKZF3 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Aiolos/IKZF3. This antibody reacts with human,primate. The Aiolos/IKZF3 Antibody - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry.
target :
Aiolos/IKZF3
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A portion of amino acids 350-400 of human IKZF3 was used as the immunogen.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Primate
gene symbol :
IKZF3
accessionNumbers :
Q9UKT9
applications :
IF/IHC,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry
USD :
409 USD
alt names :
AIO, AIOLOS, IKAROS family zinc finger 3 (Aiolos), Ikaros family zinc finger protein 3, zinc finger protein Aiolos, ZNFN1A3subfamily 1A, 3 (Aiolos)
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.