TGR5/GPBAR1 Antibody - BSA Free | Novus Biologicals NBP2-23669 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TGR5/GPBAR1 Antibody - BSA Free

catalog :

NBP2-23669

quantity :

0.1 ml (also 0.025 ml)

price :

499 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 20

Reference
Zhong S, Liu F, Giniatullin R, Jolkkonen J, Li Y, Zhou Z, et al. Blockade of CCR5 suppresses paclitaxel-induced peripheral neuropathic pain caused by increased deoxycholic acid. Cell Rep. 2023;42:113386 pubmed publisher
Biagioli M, Marchian xf2 S, Di Giorgio C, Bordoni M, Urbani G, Bellini R, et al. Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease. Biochem Pharmacol. 2023;218:115900 pubmed publisher
Zou Y, Ghaderpour A, Munkhbileg B, Seo S, Seong S. Taurodeoxycholate ameliorates DSS-induced colitis in mice. Int Immunopharmacol. 2023;122:110628 pubmed publisher
Han B, Lv X, Liu G, Li S, Fan J, Chen L, et al. Gut microbiota-related bile acid metabolism-FXR/TGR5 axis impacts the response to anti-α4β7-integrin therapy in humanized mice with colitis. Gut Microbes. 2023;15:2232143 pubmed publisher
Di Giorgio C, Bellini R, Lupia A, Massa C, Bordoni M, Marchian xf2 S, et al. Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma. Front Oncol. 2023;13:1140730 pubmed publisher
Tawulie D, Jin L, Shang X, Li Y, Sun L, Xie H, et al. Jiang-Tang-San-Huang pill alleviates type 2 diabetes mellitus through modulating the gut microbiota and bile acids metabolism. Phytomedicine. 2023;113:154733 pubmed publisher
Zhao W, Chen L, Tan W, Li Y, Sun L, Zhu X, et al. Mannan Oligosaccharides Promoted Skeletal Muscle Hypertrophy through the Gut Microbiome and Microbial Metabolites in Mice. Foods. 2023;12: pubmed publisher
Wang L, Zhao G, Wang X, Liu X, Li Y, Qiu L, et al. Glycochenodeoxycholate Affects Iron Homeostasis via Up-Regulating Hepcidin Expression. Nutrients. 2022;14: pubmed publisher
Xu J, Xie S, Chi S, Zhang S, Cao J, Tan B. Protective effects of taurocholic acid on excessive hepatic lipid accumulation via regulation of bile acid metabolism in grouper. Food Funct. 2022;13:3050-3062 pubmed publisher
Xu J, Li X, Yao X, Xie S, Chi S, Zhang S, et al. Protective Effects of Bile Acids Against Hepatic Lipid Accumulation in Hybrid Grouper Fed a High-Lipid Diet. Front Nutr. 2022;9:813249 pubmed publisher
Sun S, Guo H, Liang N, Wu T, Zhang C, Li H. GPBAR1 promotes proliferation and is related to poor prognosis of high-grade glioma via inducing MAFB expression. Histol Histopathol. 2022;37:251-260 pubmed publisher
Zhai Z, Niu K, Liu H, Lin C, Tu Y, Liu Y, et al. Policosanol alleviates hepatic lipid accumulation by regulating bile acids metabolism in C57BL6/mice through AMPK-FXR-TGR5 cross-talk. J Food Sci. 2021;86:5466-5478 pubmed publisher
Zhai Z, Niu K, Liu Y, Lin C, Wu X. The Gut Microbiota-Bile Acids-TGR5 Axis Mediates Eucommia ulmoides Leaf Extract Alleviation of Injury to Colonic Epithelium Integrity. Front Microbiol. 2021;12:727681 pubmed publisher
Trah J, Arand J, Oh J, Pagerols Raluy L, Trochimiuk M, Appl B, et al. Lithocholic bile acid induces apoptosis in human nephroblastoma cells: a non-selective treatment option. Sci Rep. 2020;10:20349 pubmed publisher
Ter Braake A, Smit A, Bos C, van Herwaarden A, Alkema W, van Essen H, et al. Magnesium prevents vascular calcification in Klotho deficiency. Kidney Int. 2020;97:487-501 pubmed publisher
Miko E, Vida A, Kovacs T, Ujlaki G, Trencsenyi G, Márton J, et al. Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness. Biochim Biophys Acta Bioenerg. 2018;1859:958-974 pubmed publisher
Mace M, Gravesen E, Nordholm A, Hofman Bang J, Secher T, Olgaard K, et al. Kidney fibroblast growth factor 23 does not contribute to elevation of its circulating levels in uremia. Kidney Int. 2017;92:165-178 pubmed publisher
Suzuki T, Seki S, Hiramoto K, Naganuma E, Kobayashi E, Yamaoka A, et al. Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus. Nat Commun. 2017;8:14577 pubmed publisher
Liu E, Martins J, Raimann A, Chae B, Brooks D, Jorgetti V, et al. 1,25-Dihydroxyvitamin D Alone Improves Skeletal Growth, Microarchitecture, and Strength in a Murine Model of XLH, Despite Enhanced FGF23 Expression. J Bone Miner Res. 2016;31:929-39 pubmed publisher
Robijn S, Vervaet B, D Haese P, Verhulst A. Evaluation of intestinal phosphate binding to improve the safety profile of oral sodium phosphate bowel cleansing. PLoS ONE. 2015;10:e0116590 pubmed publisher

product information

master code :

NBP2-23669

SKU :

NBP2-23669

product name :

TGR5/GPBAR1 Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The TGR5/GPBAR1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TGR5/GPBAR1. This antibody reacts with human,mouse,rat. The TGR5/GPBAR1 Antibody - BSA Free has been validated for the following applications: Western Blot,IF/IHC,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Knockdown Validated.

target :

TGR5/GPBAR1

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Synthetic peptide from C-terminus of the human TGR5/GPBAR1 protein [UniProt Q8TDU6]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Rat

gene symbol :

GPBAR1

Antibody validation :

Knockout/Knockdown

accessionNumbers :

Q8TDU6

applications :

Western Blot,IF/IHC,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Knockdown Validated

USD :

499 USD

alt names :

BG37hBG37, G protein-coupled bile acid receptor 1, GPCR19, GPR131, G-protein coupled bile acid receptor 1, G-protein coupled bile acid receptor BG37, G-protein coupled receptor GPCR19, M-BARhGPCR19, membrane bile acid receptor, Membrane-type receptor for bile acids, MGC40597, TGR5GPCR

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage