This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mouse Monoclonal TRANCE/TNFSF11/RANK L Antibody (12A668) [Biotin]
catalog :
NBP2-23647
quantity :
0.1 ml
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
12A668
reactivity :
human, mouse, rat
citations: 9
Reference
Hu P, Chu G, Zhu G, Yang H, Luthringer D, Prins G, et al. Multiplexed quantum dot labeling of activated c-Met signaling in castration-resistant human prostate cancer. PLoS ONE. 2011;6:e28670 pubmed publisher
Pearse R, Sordillo E, Yaccoby S, Wong B, Liau D, Colman N, et al. Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. Proc Natl Acad Sci U S A. 2001;98:11581-6 pubmed
Shin M, Matsuo K, Tada T, Fukushima H, Furuta H, Ozeki S, et al. The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone invasion by oral squamous cell carcinoma cells. Carcinogenesis. 2011;32:1634-40 pubmed publisher
Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, et al. Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. J Immunol. 2001;166:3574-9 pubmed
Parrula C, Zimmerman B, Nadella P, Shu S, Rosol T, Fernandez S, et al. Expression of tumor invasion factors determines systemic engraftment and induction of humoral hypercalcemia in a mouse model of adult T-cell leukemia. Vet Pathol. 2009;46:1003-14 pubmed publisher
Rubin J, Chung L, Fan X, Zhu L, Murphy T, Nanes M, et al. Prostate carcinoma cells that have resided in bone have an upregulated IGF-I axis. Prostate. 2004;58:41-9 pubmed
Fiumara P, Snell V, Li Y, Mukhopadhyay A, Younes M, Gillenwater A, et al. Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. Blood. 2001;98:2784-90 pubmed
Sandra F, Hendarmin L, Kukita T, Nakao Y, Nakamura N, Nakamura S. Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone. Oral Oncol. 2005;41:637-44 pubmed
Ghoreishi M, Bach P, Obst J, Komba M, Fleet J, Dutz J. Expansion of antigen-specific regulatory T cells with the topical vitamin d analog calcipotriol. J Immunol. 2009;182:6071-8 pubmed publisher
product information
Catalog Number :
NBP2-23647
Product Name :
Mouse Monoclonal TRANCE/TNFSF11/RANK L Antibody (12A668) [Biotin]
List Price :
369 USD
product type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
CD254, CD254 antigen, OPGLOPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKLreceptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TRANCEODFhRANKL2, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand superfamily member 11
Buffer :
PBS
Clonality :
Monoclonal
Clone :
12A668
Conjugate :
Biotin
Application Summary :
ELISA
Host :
Mouse
Immunogen :
A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse TRANCE was used as immunogen (NP_003692).
Isotype :
IgG1 Kappa
Preservative :
0.05% Sodium Azide
Purity :
Protein G purified
CrossReactivity :
Human, Mouse, Rat
Storage :
Store at 4C. Do not freeze.
Swissprot Human :
O14788
TMW :
35
Uses :
Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Research Area :
Cancer
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.