product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
RTEL1 Antibody - BSA Free
catalog :
NBP2-22360
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, western blot knockout validation
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig s1b
Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton S. Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe. Cell. 2018;172:439-453.e14 pubmed publisher
Sobinoff A, Di Maro S, Low R, Benedetti R, Tomassi S, D Aniello A, et al. Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells. Cell Chem Biol. 2023;30:1652-1665.e6 pubmed publisher
Higa M, Matsuda Y, Fujii J, Sugimoto N, Yoshida K, Fujita M. TRF2-mediated ORC recruitment underlies telomere stability upon DNA replication stress. Nucleic Acids Res. 2021;49:12234-12251 pubmed publisher
Summers P, Lewis B, Gonzalez Garcia J, Porreca R, Lim A, Cadinu P, et al. Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy. Nat Commun. 2021;12:162 pubmed publisher
Kotsantis P, Segura Bayona S, Margalef P, Marzec P, Ruis P, Hewitt G, et al. RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions. Cell Rep. 2020;33:108546 pubmed publisher
Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, et al. CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle. Nature. 2019;: pubmed publisher
Matsuoka S, Hashimoto D, Kadowaki M, Ohigashi H, Hayase E, Yokoyama E, et al. The myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease. Haematologica. 2019;: pubmed publisher
Chan Y, Fugger K, West S. Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations. Nat Cell Biol. 2018;20:92-103 pubmed publisher
Zimmermann M, Aguilera F, Castellucci M, Rossato M, Costa S, Lunardi C, et al. Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils. Nat Commun. 2015;6:6061 pubmed publisher
product information
master code :
NBP2-22360
SKU :
NBP2-22360
product name :
RTEL1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The RTEL1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to RTEL1. This antibody reacts with human,mouse. The RTEL1 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunoprecipitation,Immunocytochemistry/ Immunofluorescence.
target :
RTEL1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.26 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A genomic peptide made to an internal region of the human RTEL1 protein (within residues 800-1000). [Swiss-Prot Q9NZ71]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
RTEL1
accessionNumbers :
Q9NZ71
applications :
Western Blot,Immunoprecipitation,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
C20orf41, regulator of telomere elongation helicase 1, regulator of telomere length
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.