product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GOLGB1/Giantin Antibody - BSA Free
catalog :
NBP2-22321
quantity :
100 ul
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
6B4
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 11
Reference
Macke A, Divita T, Pachikov A, Mahalingam S, Bellamkonda R, Rasineni K, et al. Alcohol-induced Golgiphagy is triggered by the downregulation of Golgi GTPase RAB3D. Autophagy. 2024;20:1537-1558 pubmed publisher
Macke A, Pachikov A, Divita T, Morris M, Lagrange C, Holzapfel M, et al. Targeting the ATF6-Mediated ER Stress Response and Autophagy Blocks Integrin-Driven Prostate Cancer Progression. Mol Cancer Res. 2023;21:958-974 pubmed publisher
Zhai B, Li Y, Kotapalli S, Bacha J, Brown D, Steinø A, et al. Dianhydrogalactitol synergizes with topoisomerase poisons to overcome DNA repair activity in tumor cells. Cell Death Dis. 2020;11:577 pubmed publisher
Frisbie C, Lushnikov A, Krasnoslobodtsev A, Riethoven J, Clarke J, Stepchenkova E, et al. Post-ER Stress Biogenesis of Golgi Is Governed by Giantin. Cells. 2019;8: pubmed publisher
Casey C, Thomes P, Manca S, Petrosyan A. Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells. Biomolecules. 2018;8: pubmed publisher
Zhai B, Steinø A, Bacha J, Brown D, Daugaard M. Dianhydrogalactitol induces replication-dependent DNA damage in tumor cells preferentially resolved by homologous recombination. Cell Death Dis. 2018;9:1016 pubmed publisher
Manca S, Frisbie C, Lagrange C, Casey C, Riethoven J, Petrosyan A. The Role of Alcohol-Induced Golgi Fragmentation for Androgen Receptor Signaling in Prostate Cancer. Mol Cancer Res. 2019;17:225-237 pubmed publisher
Luchsinger C, Aguilar M, Burgos P, Ehrenfeld P, Mardones G. Functional disruption of the Golgi apparatus protein ARF1 sensitizes MDA-MB-231 breast cancer cells to the antitumor drugs Actinomycin D and Vinblastine through ERK and AKT signaling. PLoS ONE. 2018;13:e0195401 pubmed publisher
Berger A, Cortese G, Amodeo K, Weihofen A, Letai A, LaVoie M. Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release. Hum Mol Genet. 2009;18:4317-28 pubmed publisher
Bernard Gallon D, Dechelotte P, Le Corre L, Chalabi N, Vissac Sabatier C, Bignon Y. Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia. Anticancer Res. 2004;24:321-4 pubmed
Li S, Ting N, Zheng L, Chen P, Ziv Y, Shiloh Y, et al. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature. 2000;406:210-5 pubmed
product information
master code :
NBP2-22321
SKU :
NBP2-22321
product name :
GOLGB1/Giantin Antibody - BSA Free
unit size :
100 ul
description :
The GOLGB1/Giantin Antibody - BSA Free from Novus is a rabbit polyclonal antibody to GOLGB1/Giantin. This antibody reacts with human. The GOLGB1/Giantin Antibody - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence.
target :
GOLGB1/Giantin
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen this antibody was made to, maps to a region between residue 425 to 475 of human Golgin B1 using the numbering given in entry NP_004478.3 (GeneID 2804).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human
gene symbol :
GOLGB1
Antibody validation :
Independent Anitbodies
accessionNumbers :
NP_004478.3
applications :
Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence
USD :
459 USD
alt names :
372 kDa Golgi complex-associated protein, GCP, GCP372GIANTIN, giantin, golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal)1,macrogolgin, golgi integral membrane protein 1, golgin B1, golgin B1, golgi integral membrane protein, Golgin subfamily B member 1, GOLIM1, Macrogolgin
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.