product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
LAMP-2/CD107b Antibody (H4B4) - BSA Free
catalog :
NBP2-22217
quantity :
0.1 ml (also 0.025 ml)
price :
419 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H4B4
reactivity :
human, mouse, rat, chicken
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 117
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 1d
  • immunocytochemistry; human; 1:200; fig 5b
Nguyen H, Noguchi S, Sugie K, Matsuo Y, Nguyen C, Koito H, et al. Small-Vessel Vasculopathy Due to Aberrant Autophagy in LAMP-2 Deficiency. Sci Rep. 2018;8:3326 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig s2c
Pillai S, Mahmud I, Mahar R, Griffith C, Langsen M, Nguyen J, et al. Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy. Cell Rep. 2022;39:110796 pubmed publisher
  • immunocytochemistry; human
Bhandari D, Trejo J, Benovic J, Marchese A. Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4. J Biol Chem. 2007;282:36971-9 pubmed
  • immunocytochemistry; human
Iwata A, Riley B, Johnston J, Kopito R. HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. J Biol Chem. 2005;280:40282-92 pubmed
  • western blot; human
Zhang Y, Higashide W, Dai S, Sherman D, Zhou D. Recognition and ubiquitination of Salmonella type III effector SopA by a ubiquitin E3 ligase, HsRMA1. J Biol Chem. 2005;280:38682-8 pubmed
  • immunohistochemistry; human
Künzli B, Berberat P, Zhu Z, Martignoni M, Kleeff J, Tempia Caliera A, et al. Influences of the lysosomal associated membrane proteins (Lamp-1, Lamp-2) and Mac-2 binding protein (Mac-2-BP) on the prognosis of pancreatic carcinoma. Cancer. 2002;94:228-39 pubmed
  • immunohistochemistry; human
  • western blot; human
Nishino I, Fu J, Tanji K, Yamada T, Shimojo S, Koori T, et al. Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature. 2000;406:906-10 pubmed
  • immunocytochemistry; human
Garcia del Portillo F, Stein M, Finlay B. Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell. Infect Immun. 1997;65:24-34 pubmed
Fang R, Ming T, Ng J, An Guo W, Si Yu Y, Hui Z, et al. Ciliatoside A, isolated from Peristrophe japonica, inhibits HBsAg expression and cccDNA transcription by inducing autophagy. Antiviral Res. 2023;209:105482 pubmed publisher
Lee H, Nguyen Hoang A, Lee S. Ginsenoside protopanaxadiol protects adult retinal pigment epithelial-19 cells from chloroquine by modulating autophagy and apoptosis. PLoS ONE. 2022;17:e0274763 pubmed publisher
Fathi A, Mathivanan S, Kong L, Petersen A, Harder C, Block J, et al. Chemically induced senescence in human stem cell-derived neurons promotes phenotypic presentation of neurodegeneration. Aging Cell. 2021;:e13541 pubmed publisher
Nanou A, Bourbouli M, Vetrano S, Schaeper U, Ley S, Kollias G. Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis. Cell Rep. 2021;35:109168 pubmed publisher
Hirata H, Xu X, Nishioka K, Matsuhisa F, Kitajima S, Kukita T, et al. PMEPA1 and NEDD4 control the proton production of osteoclasts by regulating vesicular trafficking. FASEB J. 2021;35:e21281 pubmed publisher
Yuniati L, Lauriola A, Gerritsen M, Abreu S, Ni E, Tesoriero C, et al. Ubiquitylation of the ER-Shaping Protein Lunapark via the CRL3KLHL12 Ubiquitin Ligase Complex. Cell Rep. 2020;31:107664 pubmed publisher
Nourreddine S, Lavoie G, Paradis J, Ben El Kadhi K, Méant A, Aubert L, et al. NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay. Cell Rep. 2020;31:107660 pubmed publisher
Price C, Jones S, Mihelcic M, Santic M, Abu Kwaik Y. Paradoxical Pro-inflammatory Responses by Human Macrophages to an Amoebae Host-Adapted Legionella Effector. Cell Host Microbe. 2020;27:571-584.e7 pubmed publisher
Thamm D, Joseph J, Rose B, Meuten T, Weishaar K. Phase-I trial of survivin inhibition with EZN-3042 in dogs with spontaneous lymphoma. BMC Vet Res. 2020;16:97 pubmed publisher
Brown M, Zhang W, Yan D, Kenath R, Le L, Wang H, et al. The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC. PLoS ONE. 2020;15:e0226917 pubmed publisher
Liang C, Zhang Z, Chen Q, Yan H, Zhang M, Zhou L, et al. Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation. J Cell Biol. 2020;219: pubmed publisher
Mirshahidi S, De Necochea Campion R, Moretta A, Williams N, Reeves M, Otoukesh S, et al. Inhibitory Effects of Indomethacin in Human MNNG/HOS Osteosarcoma Cell Line In Vitro. Cancer Invest. 2020;38:23-36 pubmed publisher
Zhou J, Liu S, Wang Y, Dai W, Zou H, Wang S, et al. Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma. Mol Cancer. 2019;18:159 pubmed publisher
Abad M, Ruppert J, Buzuk L, Wear M, Zou J, Webb K, et al. Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex. J Cell Biol. 2019;218:3912-3925 pubmed publisher
Ong S, Saeki K, Kok M, Nakagawa T, Nishimura R. YM155 enhances the cytotoxic activity of etoposide against canine osteosarcoma cells. J Vet Med Sci. 2019;81:1182-1190 pubmed publisher
Kubo T, Tsurita G, Hirohashi Y, Yasui H, Ota Y, Watanabe K, et al. Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series. Cancer Sci. 2019;110:2386-2395 pubmed publisher
Ahmed M, Baumgartner R, Aldi S, Dusart P, Hedin U, Gustafsson B, et al. Human serum albumin-based probes for molecular targeting of macrophage scavenger receptors. Int J Nanomedicine. 2019;14:3723-3741 pubmed publisher
Fujimaki M, Furuya N, Saiki S, Amo T, Imamichi Y, Hattori N. Iron supply via NCOA4-mediated ferritin degradation maintains mitochondrial functions. Mol Cell Biol. 2019;: pubmed publisher
Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, et al. Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity. Dev Cell. 2019;49:393-408.e7 pubmed publisher
Zuckerman L, Frames W, Elsissy J, Shields T, De Necochea Campion R, Mirshahidi H, et al. The effect of non-steroidal anti-inflammatory drugs on osteosarcoma cells. Eur Rev Med Pharmacol Sci. 2019;23:2681-2690 pubmed publisher
Zito P, Labbozzetta M, Notarbartolo M, Sajeva M, Poma P. Essential oil of Cyphostemma juttae (Vitaceae): Chemical composition and antitumor mechanism in triple negative breast cancer cells. PLoS ONE. 2019;14:e0214594 pubmed publisher
Wong M, Ganapathy A, Suchanec E, Laidler L, Ma T, Nighot P. Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/beclin 1. Am J Physiol Cell Physiol. 2019;316:C753-C765 pubmed publisher
Ketteler J, Panic A, Reis H, Wittka A, Maier P, Herskind C, et al. Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1. J Clin Med. 2019;8: pubmed publisher
Lionetti M, Mutti F, Soldati E, Fumagalli M, Coccè V, Colombo G, et al. Sulforaphane Cannot Protect Human Fibroblasts From Repeated, Short and Sublethal Treatments with Hydrogen Peroxide. Int J Environ Res Public Health. 2019;16: pubmed publisher
Fang E, Hou Y, Palikaras K, Adriaanse B, Kerr J, Yang B, et al. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease. Nat Neurosci. 2019;22:401-412 pubmed publisher
Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O. Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562. Gene. 2019;692:217-222 pubmed publisher
Liu T, Liu J, Chen Q, Jin S, Mi S, Shao W, et al. Expression of USP22 and the chromosomal passenger complex is an indicator of malignant progression in oral squamous cell carcinoma. Oncol Lett. 2019;17:2040-2046 pubmed publisher
Ferraro M, Di Vincenzo S, Dino P, Bucchieri S, Cipollina C, Gjomarkaj M, et al. Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. Exp Gerontol. 2019;118:78-87 pubmed publisher
Kim W, Ryu J, Kim J. CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells. Int J Mol Sci. 2019;20: pubmed publisher
Masso Welch P, Girald Berlingeri S, King Lyons N, Mandell L, Hu J, Greene C, et al. LT-IIc, A Bacterial Type II Heat-Labile Enterotoxin, Induces Specific Lethality in Triple Negative Breast Cancer Cells by Modulation of Autophagy and Induction of Apoptosis and Necroptosis. Int J Mol Sci. 2018;20: pubmed publisher
Hwang J, Park J, Kim M, Kim W, Ha K, Choi B, et al. Isolinderalactone regulates the BCL-2/caspase-3/PARP pathway and suppresses tumor growth in a human glioblastoma multiforme xenograft mouse model. Cancer Lett. 2018;443:25-33 pubmed publisher
Gonda A, Kabagwira J, Senthil G, Ferguson Bennit H, Neidigh J, Khan S, et al. Exosomal survivin facilitates vesicle internalization. Oncotarget. 2018;9:34919-34934 pubmed publisher
Jones J, Kong L, Hanna M, Hoffman B, Krencik R, Bradley R, et al. Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes. Cell Rep. 2018;25:947-958.e4 pubmed publisher
Giuliani A, Cirilli I, Prattichizzo F, Mensà E, Fulgenzi G, Sabbatinelli J, et al. The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells. Aging (Albany NY). 2018;10:2855-2873 pubmed publisher
Furuya N, Kakuta S, Sumiyoshi K, Ando M, Nonaka R, Suzuki A, et al. NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy. EMBO Rep. 2018;19: pubmed publisher
Fauzia E, Barbhuyan T, Shrivastava A, Kumar M, Garg P, Khan M, et al. Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism. Front Pharmacol. 2018;9:1034 pubmed publisher
Wang T, Huang J, Vue M, Alavian M, Goel H, Altieri D, et al. αvβ3 Integrin Mediates Radioresistance of Prostate Cancer Cells through Regulation of Survivin. Mol Cancer Res. 2019;17:398-408 pubmed publisher
Troiano G, Guida A, Aquino G, Botti G, Losito N, Papagerakis S, et al. Integrative Histologic and Bioinformatics Analysis of BIRC5/Survivin Expression in Oral Squamous Cell Carcinoma. Int J Mol Sci. 2018;19: pubmed publisher
Gock M, Mullins C, Harnack C, Prall F, Ramer R, Göder A, et al. Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line. World J Gastroenterol. 2018;24:3749-3759 pubmed publisher
Lee H, Carmena M, Liskovykh M, Peat E, Kim J, Oshimura M, et al. Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy. Cancer Res. 2018;78:6282-6296 pubmed publisher
Erdogan S, Türkekul K, Dibirdik I, Doganlar O, Doganlar Z, Bilir A, et al. Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway. Biomed Pharmacother. 2018;107:793-805 pubmed publisher
Swystun L, Lai J, Notley C, Georgescu I, Paine A, Mewburn J, et al. The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity. J Clin Invest. 2018;128:4057-4073 pubmed publisher
Novais Cruz M, Alba Abad M, van IJcken W, Galjart N, Jeyaprakash A, Maiato H, et al. Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription. elife. 2018;7: pubmed publisher
Rauch A, Carlstedt A, Emmerich C, Mustafa A, Göder A, Knauer S, et al. Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells. Oncotarget. 2018;9:27835-27850 pubmed publisher
Kiweler N, Brill B, Wirth M, Breuksch I, Laguna T, Dietrich C, et al. The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells. Arch Toxicol. 2018;92:2227-2243 pubmed publisher
Pinazza M, Ghisi M, Minuzzo S, Agnusdei V, Fossati G, Ciminale V, et al. Histone deacetylase 6 controls Notch3 trafficking and degradation in T-cell acute lymphoblastic leukemia cells. Oncogene. 2018;37:3839-3851 pubmed publisher
Dizdar L, Jünemann L, Werner T, Verde P, Baldus S, Stoecklein N, et al. Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer. Oncol Lett. 2018;15:3779-3789 pubmed publisher
Wei Q, Li J, Tang F, Yin Y, Zhao Y, Yao Q. Synthesis and biological evaluation of novel 2-arylvinyl-substituted naphtho[2,3-d]imidazolium halide derivatives as potent antitumor agents. Eur J Med Chem. 2018;144:504-516 pubmed publisher
Tastekin E, Caloglu V, Durankus N, Sut N, Turkkan G, Can N, et al. Survivin expression, HPV positivity and microvessel density in oropharyngeal carcinomas and relationship with survival time. Arch Med Sci. 2017;13:1467-1473 pubmed publisher
Liang C, Chen Q, Yi Q, Zhang M, Yan H, Zhang B, et al. A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion. EMBO Rep. 2018;19:43-56 pubmed publisher
Dizdar L, Tomczak M, Werner T, Safi S, Riemer J, Verde P, et al. Survivin and XIAP expression in distinct tumor compartments of surgically resected gastric cancer: XIAP as a prognostic marker in diffuse and mixed type adenocarcinomas. Oncol Lett. 2017;14:6847-6856 pubmed publisher
Zhang J, Jin Y, Pan J. Inhibitory effect of the anthelmintic drug pyrvinium pamoate on T315I BCR?ABL?positive CML cells. Mol Med Rep. 2017;16:9217-9223 pubmed publisher
Khan S, Simpson J, Lynch J, Turay D, Mirshahidi S, Gonda A, et al. Racial differences in the expression of inhibitors of apoptosis (IAP) proteins in extracellular vesicles (EV) from prostate cancer patients. PLoS ONE. 2017;12:e0183122 pubmed publisher
Taglieri L, Rubinacci G, Giuffrida A, Carradori S, Scarpa S. The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells. Invest New Drugs. 2018;36:28-35 pubmed publisher
Ong S, Saeki K, Kok M, Tanaka Y, Choisunirachon N, Yoshitake R, et al. Anti-tumour efficacy of etoposide alone and in combination with piroxicam against canine osteosarcoma in a xenograft model. Res Vet Sci. 2017;113:130-135 pubmed publisher
Taglieri L, DE Iuliis F, Giuffrida A, Giantulli S, Silvestri I, Scarpa S. Resistance to the mTOR inhibitor everolimus is reversed by the downregulation of survivin in breast cancer cells. Oncol Lett. 2017;14:3832-3838 pubmed publisher
Werner T, Dizdar L, Nolten I, Riemer J, Mersch S, Schütte S, et al. Survivin and XIAP - two potential biological targets in follicular thyroid carcinoma. Sci Rep. 2017;7:11383 pubmed publisher
Craparo E, Ferraro M, Pace E, Bondi M, Giammona G, Cavallaro G. Polyaspartamide-Based Nanoparticles Loaded with Fluticasone Propionate and the In Vitro Evaluation towards Cigarette Smoke Effects. Nanomaterials (Basel). 2017;7: pubmed publisher
Bradford E, Ryu S, Singh A, Lee G, Goretsky T, Sinh P, et al. Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease. J Immunol. 2017;199:1886-1897 pubmed publisher
Wang H, Jin S, Lu H, Mi S, Shao W, Zuo X, et al. Expression of survivin, MUC2 and MUC5 in colorectal cancer and their association with clinicopathological characteristics. Oncol Lett. 2017;14:1011-1016 pubmed publisher
Magadum A, Ding Y, He L, Kim T, Vasudevarao M, Long Q, et al. Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair. Cell Res. 2017;27:1002-1019 pubmed publisher
Scheer A, Knauer S, Verhaegh R. Survivin expression pattern in the intestine of normoxic and ischemic rats. BMC Gastroenterol. 2017;17:76 pubmed publisher
Tung J, Tew L, Hsu Y, Khung Y. A novel 4-arm DNA/RNA Nanoconstruct triggering Rapid Apoptosis of Triple Negative Breast Cancer Cells within 24?hours. Sci Rep. 2017;7:793 pubmed publisher
Chen B, Wei W, Ma L, Yang B, Gill R, Chua M, et al. Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling. Gastroenterology. 2017;152:2022-2036 pubmed publisher
Kim W, Cheon M, Kim J. Mitochondrial CCAR2/DBC1 is required for cell survival against rotenone-induced mitochondrial stress. Biochem Biophys Res Commun. 2017;485:782-789 pubmed publisher
Dheekollu J, Malecka K, Wiedmer A, Delecluse H, Chiang A, Altieri D, et al. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget. 2017;8:7248-7264 pubmed publisher
Kreger B, Johansen E, Cerione R, Antonyak M. The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance. Cancers (Basel). 2016;8: pubmed
Lee W, Higuchi H, Ikeda S, Macke E, Takimoto T, Pattnaik B, et al. Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. elife. 2016;5: pubmed publisher
Nonagase Y, Yonesaka K, Kawakami H, Watanabe S, Haratani K, Takahama T, et al. Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1. Oncotarget. 2016;7:84860-84871 pubmed publisher
Unruhe Knauf B, Knauer S. Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization. Methods Mol Biol. 2017;1510:47-59 pubmed
Redli P, Gasic I, Meraldi P, Nigg E, Santamaria A. The Ska complex promotes Aurora B activity to ensure chromosome biorientation. J Cell Biol. 2016;215:77-93 pubmed
Lettini G, Sisinni L, Condelli V, Matassa D, Simeon V, Maddalena F, et al. TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma. Cell Death Differ. 2016;23:1792-1803 pubmed publisher
Makii C, Oda K, Ikeda Y, Sone K, Hasegawa K, Uehara Y, et al. MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53. Oncotarget. 2016;7:75328-75338 pubmed publisher
Genshaft A, Li S, Gallant C, Darmanis S, Prakadan S, Ziegler C, et al. Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction. Genome Biol. 2016;17:188 pubmed publisher
Varughese R, Torp S. Survivin and gliomas: A literature review. Oncol Lett. 2016;12:1679-1686 pubmed
Tastekin E, Caloglu V, Puyan F, Tokuc B, Caloglu M, Yalta T, et al. Prognostic Value of Angiogenesis and Survivin Expression in Patients with Glioblastoma. Turk Neurosurg. 2016;26:484-90 pubmed publisher
Alzoubi S, Brody L, Rahman S, Mahul Mellier A, Mercado N, Ito K, et al. Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer. Oncotarget. 2016;7:44505-44521 pubmed publisher
Pace E, Di Vincenzo S, Ferraro M, Bruno A, Dino P, Bonsignore M, et al. Carbocysteine counteracts the effects of cigarette smoke on cell growth and on the SIRT1/FoxO3 axis in bronchial epithelial cells. Exp Gerontol. 2016;81:119-28 pubmed publisher
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed publisher
Wu X, Tang W, Marquez R, Li K, Highfill C, He F, et al. Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling. Oncotarget. 2016;7:11708-23 pubmed publisher
Werner T, Tamkan Ölcek Y, Dizdar L, Riemer J, Wolf A, Cupisti K, et al. Survivin and XIAP: two valuable biomarkers in medullary thyroid carcinoma. Br J Cancer. 2016;114:427-34 pubmed publisher
Lotti R, Palazzo E, Petrachi T, Dallaglio K, Saltari A, Truzzi F, et al. Survivin Modulates Squamous Cell Carcinoma-Derived Stem-Like Cell Proliferation, Viability and Tumor Formation in Vivo. Int J Mol Sci. 2016;17: pubmed publisher
Christenson J, Denny E, Kane S. t-Darpp overexpression in HER2-positive breast cancer confers a survival advantage in lapatinib. Oncotarget. 2015;6:33134-45 pubmed publisher
Fukuda T, Wada Hiraike O, Oda K, Tanikawa M, Makii C, Inaba K, et al. Putative tumor suppression function of SIRT6 in endometrial cancer. FEBS Lett. 2015;589:2274-81 pubmed publisher
Labarrade F, Bergeron L, Serre C, Lebleu A, Busuttil V, Botto J, et al. Modulating the expression of survivin and other basal epidermal proteins protects human skin from UVB damage and oxidative stress. J Cosmet Dermatol. 2015;14:191-203 pubmed publisher
Papini D, Langemeyer L, Abad M, Kerr A, Samejima I, Eyers P, et al. TD-60 links RalA GTPase function to the CPC in mitosis. Nat Commun. 2015;6:7678 pubmed publisher
Yamazaki H, Takagi S, Hosoya K, Okumura M. Influence of a survivin suppressor YM155 on the chemoresistance of canine histiocytic sarcoma cells. Vet J. 2015;205:375-80 pubmed publisher
Locke F, Menges M, Veerapathran A, Coppola D, Gabrilovich D, Anasetti C. Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma. J Immunother Cancer. 2015;3:20 pubmed publisher
Valenzuela M, Ferguson Bennit H, Gonda A, Diaz Osterman C, Hibma A, Khan S, et al. Exosomes Secreted from Human Cancer Cell Lines Contain Inhibitors of Apoptosis (IAP). Cancer Microenviron. 2015;8:65-73 pubmed publisher
Bongiovanni L, D Andrea A, Porcellato I, Ciccarelli A, Malatesta D, Romanucci M, et al. Canine cutaneous melanocytic tumours: significance of β-catenin and survivin immunohistochemical expression. Vet Dermatol. 2015;26:270-e59 pubmed publisher
Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
Mehta A, Zhang L, Boufraqech M, Liu Chittenden Y, Zhang Y, Patel D, et al. Inhibition of Survivin with YM155 Induces Durable Tumor Response in Anaplastic Thyroid Cancer. Clin Cancer Res. 2015;21:4123-32 pubmed publisher
Zhang L, Zhang Y, Mehta A, Boufraqech M, Davis S, Wang J, et al. Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer. Oncotarget. 2015;6:9073-85 pubmed
Lan L, Appelman C, Smith A, Yu J, Larsen S, Marquez R, et al. Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1. Mol Oncol. 2015;9:1406-20 pubmed publisher
Sulaiman M, Chu Z, Blanco V, Vallabhapurapu S, Franco R, Qi X. SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas. Mol Cancer. 2015;14:78 pubmed publisher
Meidhof S, Brabletz S, Lehmann W, Preca B, Mock K, Ruh M, et al. ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med. 2015;7:831-47 pubmed publisher
Bonora M, Wieckowsk M, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene. 2015;34:1608 pubmed publisher
Yamazaki H, Takagi S, Hosoya K, Okumura M. Survivin suppressor (YM155) enhances chemotherapeutic efficacy against canine histiocytic sarcoma in murine transplantation models. Res Vet Sci. 2015;99:137-44 pubmed publisher
Wu X, Yamamoto H, Nakanishi H, Yamamoto Y, Inoue A, Tei M, et al. Innovative delivery of siRNA to solid tumors by super carbonate apatite. PLoS ONE. 2015;10:e0116022 pubmed publisher
Yi X, Han T, Li Y, Long X, Li W. Simultaneous silencing of XIAP and survivin causes partial mesenchymal-epithelial transition of human pancreatic cancer cells via the PTEN/PI3K/Akt pathway. Mol Med Rep. 2015;12:601-8 pubmed publisher
Nighot P, HU C, Ma T. Autophagy enhances intestinal epithelial tight junction barrier function by targeting claudin-2 protein degradation. J Biol Chem. 2015;290:7234-46 pubmed publisher
Lu H, Cao X, Chen Q, Chen L, Chen L, Gan M. The expression and role of MEKK3 in renal clear cell carcinoma. Anat Rec (Hoboken). 2015;298:727-34 pubmed publisher
Vogt N, Abramov D, Koch K, Masque Soler N, Szczepanowski M, Klapper W. No evidence of cell cycle dysregulation in mantle cell lymphoma in vivo. Leuk Lymphoma. 2015;56:2134-40 pubmed publisher
Choi Y, Head M, Ironside J, Priola S. Uptake and degradation of protease-sensitive and -resistant forms of abnormal human prion protein aggregates by human astrocytes. Am J Pathol. 2014;184:3299-307 pubmed publisher
Artesi M, Kroonen J, Bredel M, Nguyen Khac M, Deprez M, Schoysman L, et al. Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy. Neuro Oncol. 2015;17:392-406 pubmed publisher
Althoff K, Lindner S, Odersky A, Mestdagh P, Beckers A, Karczewski S, et al. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. Int J Cancer. 2015;136:1308-20 pubmed publisher
Ramírez Labrada A, López Royuela N, Jarauta V, Galán Malo P, Azaceta G, Palomera L, et al. Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis. Clin Transl Oncol. 2015;17:121-32 pubmed publisher
Kapinas K, Kim H, Mandeville M, Martin Buley L, Croce C, Lian J, et al. microRNA-mediated survivin control of pluripotency. J Cell Physiol. 2015;230:63-70 pubmed publisher
Warren R, Green F, Stenberg P, Enns C. Distinct saturable pathways for the endocytosis of different tyrosine motifs. J Biol Chem. 1998;273:17056-63 pubmed
product information
master code :
NBP2-22217
SKU :
NBP2-22217
product name :
LAMP-2/CD107b Antibody (H4B4) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The LAMP-2/CD107b Antibody (H4B4) - BSA Free from Novus is a mouse monoclonal antibody to LAMP-2/CD107b. This antibody reacts with avian - chicken,chicken,human,mouse,rat (negative). The LAMP-2/CD107b Antibody (H4B4) - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoblotting,Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Simple Western,CyTOF-ready,Knockout Validated.
target :
LAMP-2/CD107b
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
H4B4
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
LAMP-2/CD107b Antibody (H4B4) was made using a human adherent spleen cells.
isotype :
IgG1 Kappa
purity :
Protein G purified
species :
Avian - Chicken,Chicken,Human,Mouse,Rat (Negative)
theoretical molecular weight :
45 kDa
gene symbol :
LAMP2
Antibody validation :
Knockout/Knockdown
accessionNumbers :
P13473, P13473
applications :
Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoblotting,Immunofluorescence,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Simple Western,CyTOF-ready,Knockout Validated
extended description :
Clone H4B4 was used by HLDA to establish CD designation.
USD :
419 USD
product details :
Clone H4B4 was used by HLDA to establish CD designation.
alt names :
CD107 antigen-like family member B, CD107b, CD107b antigen, LAMP2, LAMP-2, LAMP2A, LAMP-2A, LAMPB, LGP110, LGP-96, Lysosomal Associated Membrane Protein 2, lysosomal-associated membrane protein 2, lysosome-associated membrane glycoprotein 2, Lysosome-associated membrane protein 2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.