product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SLC6A3/DAT1 Antibody (mAb16) - BSA Free
catalog :
NBP2-22164
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
mAb16
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; rat
Moritz A, Foster J, Gorentla B, Mazei Robison M, Yang J, Sitte H, et al. Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding. J Biol Chem. 2013;288:20-32 pubmed publisher
  • western blot; mouse
  • western blot; rat
Foster J, Yang J, Moritz A, Challasivakanaka S, Smith M, Holy M, et al. Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux. J Biol Chem. 2012;287:29702-12 pubmed publisher
  • western blot; rat
Foster J, Vaughan R. Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. J Biol Chem. 2011;286:5175-86 pubmed publisher
  • immunoprecipitation; rat
  • western blot; rat
Cervinski M, Foster J, Vaughan R. Syntaxin 1A regulates dopamine transporter activity, phosphorylation and surface expression. Neuroscience. 2010;170:408-16 pubmed publisher
  • western blot; rat
Perry M, Leinninger G, Chen R, Luderman K, Yang H, Gnegy M, et al. Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats. J Neurochem. 2010;114:666-74 pubmed publisher
  • western blot; rat
Furman C, Chen R, Guptaroy B, Zhang M, Holz R, Gnegy M. Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy. J Neurosci. 2009;29:3328-36 pubmed publisher
  • western blot; rat
Gorentla B, Moritz A, Foster J, Vaughan R. Proline-directed phosphorylation of the dopamine transporter N-terminal domain. Biochemistry. 2009;48:1067-76 pubmed publisher
  • western blot; mouse
Chen R, Zhang M, Park S, Gnegy M. C57BL/6J mice show greater amphetamine-induced locomotor activation and dopamine efflux in the striatum than 129S2/SvHsd mice. Pharmacol Biochem Behav. 2007;87:158-63 pubmed
  • western blot; rat
Johnson L, Furman C, Zhang M, Guptaroy B, Gnegy M. Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation. Neuropharmacology. 2005;49:750-8 pubmed
  • western blot; rat
Johnson L, Guptaroy B, Lund D, Shamban S, Gnegy M. Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta. J Biol Chem. 2005;280:10914-9 pubmed
  • western blot; rat
Gaffaney J, Vaughan R. Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Mol Pharmacol. 2004;65:692-701 pubmed
Shan J, Qu Y, Zhang J, Ma L, Hashimoto K. Effects of Subdiaphragmatic Vagotomy in the MPTP-induced Neurotoxicity in the Striatum and Colon of Mice. Clin Psychopharmacol Neurosci. 2022;20:389-393 pubmed publisher
Zhang X, de Oliveira Andrade F, Zhang H, Cruz I, Clarke R, Gaur P, et al. Maternal obesity increases offspring's mammary cancer recurrence and impairs tumor immune response. Endocr Relat Cancer. 2020;27:469-482 pubmed publisher
Rabenstein M, Unverricht Yeboah M, Keuters M, Pikhovych A, Hucklenbroich J, Vay S, et al. Transcranial Current Stimulation Alters the Expression of Immune-Mediating Genes. Front Cell Neurosci. 2019;13:461 pubmed publisher
Carballo Carbajal I, Laguna A, Romero Gimenez J, Cuadros T, Bove J, Martinez Vicente M, et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis. Nat Commun. 2019;10:973 pubmed publisher
Stettner M, Lohmann B, Wolffram K, Weinberger J, Dehmel T, Hartung H, et al. Interleukin-17 impedes Schwann cell-mediated myelination. J Neuroinflammation. 2014;11:63 pubmed publisher
Bereczky Veress B, Abdelmagid N, Piehl F, Bergstrom T, Olsson T, Sköldenberg B, et al. Influence of perineurial cells and Toll-like receptors 2 and 9 on Herpes simplex type 1 entry to the central nervous system in rat encephalitis. PLoS ONE. 2010;5:e12350 pubmed publisher
Baca Jones C, Kreklywich C, Messaoudi I, Vomaske J, McCartney E, Orloff S, et al. Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells. Virology. 2009;388:78-90 pubmed publisher
product information
master code :
NBP2-22164
SKU :
NBP2-22164
product name :
SLC6A3/DAT1 Antibody (mAb16) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The SLC6A3/DAT1 Antibody (mAb16) - BSA Free from Novus is a mouse monoclonal antibody to SLC6A3/DAT1. This antibody reacts with human (negative),mouse,rat. The SLC6A3/DAT1 Antibody (mAb16) - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,ELISA,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence.
target :
SLC6A3/DAT1
category :
Primary Antibodies
buffer :
Tris-Glycine and 0.15M NaCl
clonality :
Monoclonal
clone :
mAb16
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Synthetic peptide corresponding to the N-terminus of rat DAT1. [UniProt# P23977]
isotype :
IgG1
purity :
Protein G purified
species :
Human (Negative),Mouse,Rat
gene symbol :
SLC6A3
accessionNumbers :
Q61327, P23977
applications :
Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,ELISA,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
DA transporter, DATDAT1Solute carrier family 6 member 3, sodium-dependent dopamine transporter, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.