product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
HDAC5 Antibody - BSA Free
catalog :
NBP2-22152
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
CM-A807
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 15
Reference
Lecce L, Xu Y, V Gangula B, Chandel N, Pothula V, Caudrillier A, et al. Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype. J Clin Invest. 2021;131: pubmed publisher
Kohno M, Kobayashi S, Yamamoto T, Yoshitomi R, Kajii T, Fujii S, et al. Enhancing calmodulin binding to cardiac ryanodine receptor completely inhibits pressure-overload induced hypertrophic signaling. Commun Biol. 2020;3:714 pubmed publisher
Lee J, Byun W, Kang M, Han J, Moon J, Shin M, et al. The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKα2. FEBS J. 2020;287:2087-2104 pubmed publisher
Chen J, Dai L, Goldstein A, Zhang H, Tang W, Forrest J, et al. Identification of new antiviral agents against Kaposi's sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation. PLoS Pathog. 2019;15:e1008156 pubmed publisher
Tyler C, Smoake J, Solomon E, Villicana E, Caldwell K, Allan A. Sex-Dependent Effects of the Histone Deacetylase Inhibitor, Sodium Valproate, on Reversal Learning After Developmental Arsenic Exposure. Front Genet. 2018;9:200 pubmed publisher
Xiang Q, Ju H, Li Q, Mei S, Chen D, Choi Y, et al. Human Herpesvirus 8 Interferon Regulatory Factors 1 and 3 Mediate Replication and Latency Activities via Interactions with USP7 Deubiquitinase. J Virol. 2018;92: pubmed publisher
Lee H, Li F, Choi U, Yu H, Aldrovandi G, Feng P, et al. Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. MBio. 2018;9: pubmed publisher
Baek M, Park J, Rhim C, Park Y, Kim K, Kim J, et al. Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma. Anticancer Res. 2016;36:2527-34 pubmed
Liang Q, Chang B, Lee P, Brulois K, Ge J, Shi M, et al. Identification of the Essential Role of Viral Bcl-2 for Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication. J Virol. 2015;89:5308-17 pubmed publisher
Zuo J, Hislop A, Leung C, Sabbah S, Rowe M. Kaposi's sarcoma-associated herpesvirus-encoded viral IRF3 modulates major histocompatibility complex class II (MHC-II) antigen presentation through MHC-II transactivator-dependent and -independent mechanisms: implications for oncogenesis. J Virol. 2013;87:5340-50 pubmed publisher
Marcos Villar L, Gallego P, Munoz Fontela C, de la Cruz Herrera C, Campagna M, Gonzalez D, et al. Kaposi's sarcoma-associated herpesvirus lana2 protein interacts with the pocket proteins and inhibits their sumoylation. Oncogene. 2014;33:495-503 pubmed publisher
Marcos Villar L, Campagna M, Lopitz Otsoa F, Gallego P, González Santamaría J, Gonzalez D, et al. Covalent modification by SUMO is required for efficient disruption of PML oncogenic domains by Kaposi's sarcoma-associated herpesvirus latent protein LANA2. J Gen Virol. 2011;92:188-94 pubmed publisher
Sarek G, Järviluoma A, Moore H, Tojkander S, Vartia S, Biberfeld P, et al. Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency. PLoS Pathog. 2010;6:e1000818 pubmed publisher
Marcos Villar L, Lopitz Otsoa F, Gallego P, Munoz Fontela C, González Santamaría J, Campagna M, et al. Kaposi's sarcoma-associated herpesvirus protein LANA2 disrupts PML oncogenic domains and inhibits PML-mediated transcriptional repression of the survivin gene. J Virol. 2009;83:8849-58 pubmed publisher
Shin Y, Joo C, Gack M, Lee H, Jung J. Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression. Cancer Res. 2008;68:1751-9 pubmed publisher
product information
master code :
NBP2-22152
SKU :
NBP2-22152
product name :
HDAC5 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The HDAC5 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to HDAC5. This antibody reacts with human,mouse,primate,rat. The HDAC5 Antibody - BSA Free has been validated for the following applications: Chemotaxis,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation,Immunohistochemistry,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence.
target :
HDAC5
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an N-terminal portion of the human HDAC5 protein (between residues 1-100) [UniProt Q9UQL6]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Primate,Rat
theoretical molecular weight :
130 kDa
gene symbol :
HDAC5
Antibody validation :
Biological Validation
accessionNumbers :
Q9UQL6
applications :
Chemotaxis,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation,Immunohistochemistry,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
Antigen NY-CO-9, EC 3.5.1.98, FLJ90614, HD5, histone deacetylase 5, KIAA0600, NY-CO-9
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.