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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
alpha-Smooth Muscle Actin Antibody (4A4)
catalog :
NBP2-22120
quantity :
0.1 ml (also 0.025 ml)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4A4
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 19
Reference
Cheng S, Zou Y, Zhang M, Bai S, Tao K, Wu J, et al. Single-cell RNA sequencing reveals the heterogeneity and intercellular communication of hepatic stellate cells and macrophages during liver fibrosis. MedComm (2020). 2023;4:e378 pubmed publisher
Peng L, Jin X, He Q, Gao X, Wang W, Zeng X, et al. Remodelling landscape of tissue-engineered bladder with porcine small intestine submucosa using single-cell RNA sequencing. Cell Prolif. 2023;56:e13343 pubmed publisher
Liu C, Rioja I, Bakr A, Veldwijk M, Sperk E, Herskind C, et al. Selective inhibitors of bromodomain BD1 and BD2 of BET proteins modulate radiation-induced profibrotic fibroblast responses. Int J Cancer. 2022;151:275-286 pubmed publisher
Kamothi D, Kant V, Jangir B, Joshi V, Ahuja M, Kumar V. Novel preparation of bilirubin-encapsulated pluronic F-127 nanoparticles as a potential biomaterial for wound healing. Eur J Pharmacol. 2022;919:174809 pubmed publisher
Kant V, Jangir B, Sharma M, Kumar V, Joshi V. Topical application of quercetin improves wound repair and regeneration in diabetic rats. Immunopharmacol Immunotoxicol. 2021;43:536-553 pubmed publisher
Khodja Y, Samuels M. Ethanol-mediated upregulation of APOA1 gene expression in HepG2 cells is independent of de novo lipid biosynthesis. Lipids Health Dis. 2020;19:144 pubmed publisher
Choudhary A, Kant V, Jangir B, Joshi V. Quercetin loaded chitosan tripolyphosphate nanoparticles accelerated cutaneous wound healing in Wistar rats. Eur J Pharmacol. 2020;880:173172 pubmed publisher
Levy D, de Melo T, Oliveira B, Paz J, de Freitas F, Reichert C, et al. 7-Ketocholesterol and cholestane-triol increase expression of SMO and LXRα signaling pathways in a human breast cancer cell line. Biochem Biophys Rep. 2019;19:100604 pubmed publisher
Zhou P, Zhang X, Guo M, Guo R, Wang L, Zhang Z, et al. Ginsenoside Rb1 ameliorates CKD-associated vascular calcification by inhibiting the Wnt/β-catenin pathway. J Cell Mol Med. 2019;23:7088-7098 pubmed publisher
Zhou Y, Miles J, Tavori H, Lin M, Khoshbouei H, Borchelt D, et al. PMP22 regulates cholesterol trafficking and ABCA1-mediated cholesterol efflux. J Neurosci. 2019;: pubmed publisher
Chakrabarti J, Holokai L, Syu L, Steele N, Chang J, Wang J, et al. Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer. Oncotarget. 2018;9:37439-37457 pubmed publisher
JENSEN T, Wanczyk H, Sharma I, Mitchell A, Sayej W, Finck C. Polyurethane scaffolds seeded with autologous cells can regenerate long esophageal gaps: An esophageal atresia treatment model. J Pediatr Surg. 2018;: pubmed publisher
Guo M, Guo G, Xiao J, Sheng X, Zhang X, Tie Y, et al. Ginsenoside Rg3 stereoisomers differentially inhibit vascular smooth muscle cell proliferation and migration in diabetic atherosclerosis. J Cell Mol Med. 2018;22:3202-3214 pubmed publisher
Yang Y, Yang Q, Yang J, Ma Y, Ding G. Angiotensin II induces cholesterol accumulation and injury in podocytes. Sci Rep. 2017;7:10672 pubmed publisher
de Souza Pinto R, Castilho G, Paim B, Machado Lima A, Inada N, Nakandakare E, et al. Inhibition of macrophage oxidative stress prevents the reduction of ABCA-1 transporter induced by advanced glycated albumin. Lipids. 2012;47:443-50 pubmed publisher
Scotti E, Hong C, Yoshinaga Y, Tu Y, Hu Y, Zelcer N, et al. Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists. Mol Cell Biol. 2011;31:1885-93 pubmed publisher
Lu Y, Su M, Huang H, Lin Li -, Yuan C. Protective effects of the citrus flavanones to PC12 cells against cytotoxicity induced by hydrogen peroxide. Neurosci Lett. 2010;484:6-11 pubmed publisher
Wang J, Zhang Z, Chou C, Liang Y, Gu Y, Ma H. Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. Am J Physiol Renal Physiol. 2009;296:F284-90 pubmed publisher
Wahrle S, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, et al. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest. 2008;118:671-82 pubmed publisher
product information
master code :
NBP2-22120
SKU :
NBP2-22120
product name :
alpha-Smooth Muscle Actin Antibody (4A4)
unit size :
0.1 ml (also 0.025 ml)
description :
The alpha-Smooth Muscle Actin Antibody (4A4) from Novus is a mouse monoclonal antibody to alpha-Smooth Muscle Actin. This antibody reacts with human,monkey,mouse,rat. The alpha-Smooth Muscle Actin Antibody (4A4) has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Immunohistochemistry-Frozen.
target :
alpha-Smooth Muscle Actin
category :
Primary Antibodies
buffer :
Ascites
clonality :
Monoclonal
clone :
4A4
conjugate :
Unconjugated
host :
Mouse
immunogen :
Synthesized peptide of human alpha-Smooth Muscle Actin.
isotype :
IgG1
purity :
Unpurified
species :
Human,Monkey,Mouse,Rat
theoretical molecular weight :
42 kDa
gene symbol :
ACTA2
accessionNumbers :
P62736
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Immunohistochemistry-Frozen
USD :
469 USD
alt names :
AAT6, actin, alpha 2, smooth muscle, aorta, actin, aortic smooth muscle, ACTSA, ACTVS, alpha 2 actin, alpha SMA, alpha smooth muscle actin, alpha-actin-2, alpha-SMA, a-sma, Cell growth-inhibiting gene 46 protein, growth-inhibiting gene 46, sma, smooth muscle actin
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.