product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Lamin A + C Antibody - BSA Free
catalog :
NBP2-19324
quantity :
0.1 ml
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 8
Reference
Yang J, Sun B, Wang Z, Li X, Gao J, Qian J, et al. Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption. Cell Death Dis. 2023;14:738 pubmed publisher
Brown S, x160 olti x107 D, Synowsky S, Shirran S, Chilcott E, Shorrock H, et al. AAV9-mediated SMN gene therapy rescues cardiac desmin but not lamin A/C and elastin dysregulation in Smn2B/- spinal muscular atrophy mice. Hum Mol Genet. 2023;32:2950-2965 pubmed publisher
Edara V, Nooka S, Proulx J, Stacy S, Ghorpade A, Borgmann K. β-Catenin Regulates Wound Healing and IL-6 Expression in Activated Human Astrocytes. Biomedicines. 2020;8: pubmed publisher
Šoltić D, Shorrock H, Allardyce H, Wilson E, Holt I, Synowsky S, et al. Lamin A/C dysregulation contributes to cardiac pathology in a mouse model of severe spinal muscular atrophy. Hum Mol Genet. 2019;: pubmed publisher
Yoshida M, Ogawa R, Yoshida H, Maeshima A, Kanai Y, Kinoshita T, et al. TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast. Br J Cancer. 2015;113:1244-8 pubmed publisher
Napier C, Huschtscha L, Harvey A, Bower K, Noble J, Hendrickson E, et al. ATRX represses alternative lengthening of telomeres. Oncotarget. 2015;6:16543-58 pubmed
Pipinikas C, Dibra H, Karpathakis A, Feber A, Novelli M, Oukrif D, et al. Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours. Endocr Relat Cancer. 2015;22:L13-8 pubmed publisher
Fishbein L, Khare S, Wubbenhorst B, Desloover D, D Andrea K, Merrill S, et al. Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas. Nat Commun. 2015;6:6140 pubmed publisher
product information
master code :
NBP2-19324
SKU :
NBP2-19324
product name :
Lamin A + C Antibody - BSA Free
unit size :
0.1 ml
description :
The Lamin A + C Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Lamin A + C. This antibody reacts with human,mouse,rat. The Lamin A + C Antibody - BSA Free has been validated for the following applications: Immunohistochemistry-Frozen,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Knockout Validated,Immunocytochemistry/ Immunofluorescence.
target :
Lamin A + C
category :
Primary Antibodies
buffer :
PBS (pH 7), 20% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Recombinant protein encompassing a sequence within the center region of human Lamin A + C. The exact sequence is proprietary.
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
theoretical molecular weight :
74 kDa
gene symbol :
LMNA
Antibody validation :
Knockout/Knockdown
applications :
Immunohistochemistry-Frozen,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Knockout Validated,Immunocytochemistry/ Immunofluorescence
USD :
459 USD
alt names :
CDCD1, CDDC, CMD1A, CMT2B1, dilated 1A (autosomal dominant), EMD2, FPLD, HGPSFPL, lamin A/C, lamin A/C-like 1, lamin-A/C, LDP1, LFP, LGMD1B, limb girdle muscular dystrophy 1B (autosomal dominant), LMN1IDC, LMNC, LMNL1, prelamin-A/C, PRO1,70 kDa lamin, progeria 1 (Hutchinson-Gilford type), renal carcinoma antigen NY-REN-32
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.