product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
ATG13 [p Ser355] Antibody - BSA Free
catalog :
NBP2-19127
quantity :
0.1 mg (also 0.025 mg)
price :
529 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, flow cytometry
more info or order :
citations: 20
Reference
Simpson L, Fulcher L, Sathe G, Brewer A, Zhao J, Squair D, et al. An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation. Cell Chem Biol. 2023;30:188-202.e6 pubmed publisher
Dent P, Booth L, Poklepovic A, Kirkwood J. Neratinib kills B-RAF V600E melanoma via ROS-dependent autophagosome formation and death receptor signaling. Pigment Cell Melanoma Res. 2021;: pubmed publisher
Dent P, Booth L, Roberts J, Poklepovic A, Cridebring D, Reiman E. Inhibition of heat shock proteins increases autophagosome formation, and reduces the expression of APP, Tau, SOD1 G93A and TDP-43. Aging (Albany NY). 2021;13:17097-17117 pubmed publisher
Dent P, Booth L, Poklepovic A, Von Hoff D, Martinez J, Zhou Y, et al. Osimertinib-resistant NSCLC cells activate ERBB2 and YAP/TAZ and are killed by neratinib. Biochem Pharmacol. 2021;190:114642 pubmed publisher
Booth L, West C, Von Hoff D, Kirkwood J, Dent P. GZ17-6.02 Interacts With [MEK1/2 and B-RAF Inhibitors] to Kill Melanoma Cells. Front Oncol. 2021;11:656453 pubmed publisher
Zachari M, Longo M, Ganley I. Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity. Life Sci Alliance. 2020;3: pubmed publisher
Simpson L, MacArtney T, Nardin A, Fulcher L, R th S, Testa A, et al. Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System. Cell Chem Biol. 2020;27:1164-1180.e5 pubmed publisher
Booth L, Poklepovic A, Dent P. Neratinib decreases pro-survival responses of [sorafenib + vorinostat] in pancreatic cancer. Biochem Pharmacol. 2020;178:114067 pubmed publisher
Roberts J, Poklepovic A, Booth L, Dent P. The multi-kinase inhibitor lenvatinib interacts with the HDAC inhibitor entinostat to kill liver cancer cells. Cell Signal. 2020;70:109573 pubmed publisher
Dent P, Booth L, Roberts J, Poklepovic A, Hancock J. Fingolimod Augments Monomethylfumarate Killing of GBM Cells. Front Oncol. 2020;10:22 pubmed publisher
Zachari M, Rainard J, Pandarakalam G, Robinson L, Gillespie J, Rajamanickam M, et al. The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets. Biochem J. 2020;477:801-814 pubmed publisher
Dent P, Booth L, Roberts J, Poklepovic A, Hancock J. (Curcumin+sildenafil) enhances the efficacy of 5FU and anti-PD1 therapies in vivo. J Cell Physiol. 2020;: pubmed publisher
Booth L, Roberts J, West C, Von Hoff D, Dent P. GZ17-6.02 initiates DNA damage causing autophagosome-dependent HDAC degradation resulting in enhanced anti-PD1 checkpoint inhibitory antibody efficacy. J Cell Physiol. 2020;: pubmed publisher
Demas D, Demo S, Fallah Y, Clarke R, Nephew K, Althouse S, et al. Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer. Front Oncol. 2019;9:686 pubmed publisher
Booth L, Roberts J, Poklepovic A, Dent P. The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by Neratinib. Front Oncol. 2019;9:650 pubmed publisher
Dent P, Booth L, Roberts J, Liu J, Poklepovic A, Lalani A, et al. Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. Oncogene. 2019;38:5890-5904 pubmed publisher
Shoemaker C, Huang T, Weir N, Polyakov N, Schultz S, Denic V. CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor. PLoS Biol. 2019;17:e2007044 pubmed publisher
Booth L, Roberts J, Spiegel S, Poklepovic A, Dent P. Fingolimod augments Pemetrexed killing of non-small cell lung cancer and overcomes resistance to ERBB inhibition. Cancer Biol Ther. 2019;20:597-607 pubmed publisher
Booth L, Roberts J, Samuel P, Avogadri Connors F, Cutler R, Lalani A, et al. The irreversible ERBB1/2/4 inhibitor neratinib interacts with the PARP1 inhibitor niraparib to kill ovarian cancer cells. Cancer Biol Ther. 2018;19:525-533 pubmed publisher
Gu Y, SHEA J, Slattum G, Firpo M, Alexander M, Mulvihill S, et al. Defective apical extrusion signaling contributes to aggressive tumor hallmarks. elife. 2015;4:e04069 pubmed publisher
product information
master code :
NBP2-19127
SKU :
NBP2-19127
product name :
ATG13 [p Ser355] Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The ATG13 [p Ser355] Antibody - BSA Free from Novus is a rabbit polyclonal antibody to ATG13. This antibody reacts with human,mouse. The ATG13 [p Ser355] Antibody - BSA Free has been validated for the following applications: Western Blot,Knockdown Validated,Flow Cytometry,ELISA.
target :
ATG13
category :
Primary Antibodies
buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
ATG13 [p Ser355] Antibody was prepared by repeated immunizations with a synthetic peptide corresponding to the region near Ser355 of ATG13. (Uniprot: O75143)
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
specificity :
This affinity-purified antibody directed against the phosphorylated form of human ATG13 protein isoform 1 at the [p Ser355] residue, and to isoforms 2 and 3 at the [p Ser318] residue (Uniprot: O75143)
gene symbol :
ATG13
accessionNumbers :
O75143
applications :
Western Blot,Knockdown Validated,Flow Cytometry,ELISA
USD :
529 USD
alt names :
autophagy-related protein 13, autophagy related 13, KIAA0652
storage :
Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.