product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
AIF-1/Iba1 Antibody - Azide and BSA Free
catalog :
NBP2-19019
quantity :
100 ul
price :
449 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
10C3
reactivity :
human, mouse, rat, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 48
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 6c, 6d
Ma N, Li G, Fu X. Protective role of activating transcription factor 3 against neuronal damage in rats with cerebral ischemia. Brain Behav. 2022;12:e2522 pubmed publisher
Tylek K, Trojan E, Le x15b kiewicz M, Ghafir El Idrissi I, Lacivita E, Leopoldo M, et al. Microglia Depletion Attenuates the Pro-Resolving Activity of the Formyl Peptide Receptor 2 Agonist AMS21 Related to Inhibition of Inflammasome NLRP3 Signalling Pathway: A Study of Organotypic Hippocampal Cultures. Cells. 2023;12: pubmed publisher
Williams E, Xue Y, Lee J, Fitzpatrick E, Kong Y, Reichard W, et al. Deep spatial profiling of Venezuelan equine encephalitis virus reveals increased genetic diversity amidst neuroinflammation and cell death during brain infection. J Virol. 2023;97:e0082723 pubmed publisher
Merlo S, Caruso G, Korde D, Khodorovska A, Humpel C, Sortino M. Melatonin Activates Anti-Inflammatory Features in Microglia in a Multicellular Context: Evidence from Organotypic Brain Slices and HMC3 Cells. Biomolecules. 2023;13: pubmed publisher
Tsujikawa S, DeMeulenaere K, Centeno M, Ghazisaeidi S, Martin M, Tapies M, et al. Regulation of neuropathic pain by microglial Orai1 channels. Sci Adv. 2023;9:eade7002 pubmed publisher
Ciechanowska A, Rojewska E, Piotrowska A, Barut J, Pawlik K, Ciapa x142 a K, et al. New insights into the analgesic properties of the XCL1/XCR1 and XCL1/ITGA9 axes modulation under neuropathic pain conditions - evidence from animal studies. Front Immunol. 2022;13:1058204 pubmed publisher
Guo L, Reed K, Carter A, Cheng Y, Roodsari S, Martinez Pineda D, et al. Sleep-Disturbance-Induced Microglial Activation Involves CRH-Mediated Galectin 3 and Autophagy Dysregulation. Cells. 2022;12: pubmed publisher
Pawlik K, Ciapa x142 a K, Ciechanowska A, Kwiatkowski K, Mika J. Pharmacological Evidence of the Important Roles of CCR1 and CCR3 and Their Endogenous Ligands CCL2/7/8 in Hypersensitivity Based on a Murine Model of Neuropathic Pain. Cells. 2022;12: pubmed publisher
Henriques A, Rouvi xe8 re L, Giorla E, Farrugia C, El Waly B, Poindron P, et al. Alpha-Synuclein: The Spark That Flames Dopaminergic Neurons, In Vitro and In Vivo Evidence. Int J Mol Sci. 2022;23: pubmed publisher
Tyagi A, Wu S, Sharma S, Wu K, Zhao D, Deshpande R, et al. Exosomal miR-4466 from nicotine-activated neutrophils promotes tumor cell stemness and metabolism in lung cancer metastasis. Oncogene. 2022;41:3079-3092 pubmed publisher
Xiang X, Tang X, Yu Y, Xie S, Liu L, Chen M, et al. Role of lipocalin-2 in surgery-induced cognitive decline in mice: a signal from neuron to microglia. J Neuroinflammation. 2022;19:92 pubmed publisher
Cheng Y, Kim W, Wellman L, Sanford L, Guo M. Short-Term Sleep Fragmentation Dysregulates Autophagy in a Brain Region-Specific Manner. Life (Basel). 2021;11: pubmed publisher
Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, et al. Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:169 pubmed publisher
Hong J, Adam R, Gao L, Hahka T, Xia Z, Wang D, et al. Macrophage activation in stellate ganglia contributes to lung injury-induced arrhythmogenesis in male rats. Acta Physiol (Oxf). 2021;232:e13657 pubmed publisher
Niesel K, Schulz M, Anthes J, Alekseeva T, Macas J, Salamero Boix A, et al. The immune suppressive microenvironment affects efficacy of radio-immunotherapy in brain metastasis. EMBO Mol Med. 2021;13:e13412 pubmed publisher
Chamera K, Trojan E, Kotarska K, Szuster Głuszczak M, Bryniarska N, Tylek K, et al. Role of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation and Subsequent Immune Challenge in the Behaviour and Microglial Cell Trajectory in Adult Offspring: A Study of the Neurodevelopmental Model of Schizophrenia. Int J Mol Sci. 2021;22: pubmed publisher
Kim J, Suh Y, Chang K. Interleukin-17 induced by cumulative mild stress promoted depression-like behaviors in young adult mice. Mol Brain. 2021;14:11 pubmed publisher
Williams A, Manouchehri N, Erskine E, Tauh K, So K, Shortt K, et al. Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injury. Nat Commun. 2020;11:5209 pubmed publisher
Liu L, Chen M, Lin K, Xiang X, Zheng Y, Zhu S. Inhibiting Caspase-12 Mediated Inflammasome Activation protects against Oxygen-Glucose Deprivation Injury in Primary Astrocytes. Int J Med Sci. 2020;17:1936-1945 pubmed publisher
Chamera K, Szuster Głuszczak M, Trojan E, Basta Kaim A. Maternal Immune Activation Sensitizes Male Offspring Rats to Lipopolysaccharide-Induced Microglial Deficits Involving the Dysfunction of CD200-CD200R and CX3CL1-CX3CR1 Systems. Cells. 2020;9: pubmed publisher
Hughes F, Hirshman N, Malick H, White S, Jin H, Harper S, et al. A possible mechanism underlying mood disorders associated with LUTS: Chronic bladder outlet obstruction causes NLRP3-dependent inflammation in the hippocampus and depressive behavior in rats. Neurourol Urodyn. 2020;: pubmed publisher
Merlo S, Luaces J, Spampinato S, Toro Urrego N, Caruso G, D Amico F, et al. SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules. 2020;10: pubmed publisher
Wang G, Xu J, Zhao J, Yin W, Liu D, Chen W, et al. Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice. Nat Commun. 2020;11:220 pubmed publisher
Hirshman N, Hughes F, Jin H, Harrison W, White S, Doan I, et al. Cyclophosphamide-induced cystitis results in NLRP3-mediated inflammation in the hippocampus and symptoms of depression in rats. Am J Physiol Renal Physiol. 2020;318:F354-F362 pubmed publisher
Chang M, Brown M, Liu Y, Gainullin V, Harris P, Romero M, et al. Cl- and H+ coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl-/H+ exchanger ClC-5. J Biol Chem. 2020;295:1464-1473 pubmed publisher
Xu C, Diao Y, Wang J, Xu H, Zhao M, Luan Z, et al. Intravenously infusing the secretome of adipose-derived mesenchymal stem cells ameliorates neuroinflammation and neurological functioning after traumatic brain injury. Stem Cells Dev. 2019;: pubmed publisher
Han T, Root J, Reyes L, Huchinson E, Hoffmann J, Lee W, et al. Human GNPTAB stuttering mutations engineered into mice cause vocalization deficits and astrocyte pathology in the corpus callosum. Proc Natl Acad Sci U S A. 2019;116:17515-17524 pubmed publisher
Kalainayakan S, Ghosh P, Dey S, FitzGerald K, Sohoni S, Konduri P, et al. Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression. Sci Rep. 2019;9:1405 pubmed publisher
Gurung S, Reuter N, Preno A, Dubaut J, Nadeau H, Hyatt K, et al. Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon. PLoS Pathog. 2019;15:e1007507 pubmed publisher
Merlo S, Spampinato S, Beneventano M, Sortino M. The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death. Sci Rep. 2018;8:7297 pubmed publisher
Yang H, Fu Y, Liu X, Shahi P, Mavlyutov T, Li J, et al. Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa. Mol Neurodegener. 2017;12:68 pubmed publisher
Hao Y, Chow A, Yip W, Li C, Wan T, Tong B, et al. G protein-coupled estrogen receptor inhibits the P2Y receptor-mediated Ca(2+) signaling pathway in human airway epithelia. Pflugers Arch. 2016;468:1489-503 pubmed publisher
Kilaparty S, Agarwal R, Singh P, Kannan K, Ali N. Endoplasmic reticulum stress-induced apoptosis accompanies enhanced expression of multiple inositol polyphosphate phosphatase 1 (Minpp1): a possible role for Minpp1 in cellular stress response. Cell Stress Chaperones. 2016;21:593-608 pubmed publisher
Putz U, Howitt J, Lackovic J, Foot N, Kumar S, Silke J, et al. Nedd4 family-interacting protein 1 (Ndfip1) is required for the exosomal secretion of Nedd4 family proteins. J Biol Chem. 2008;283:32621-7 pubmed publisher
Duriez M, Rossignol J, Sitterlin D. The hepatitis B virus precore protein is retrotransported from endoplasmic reticulum (ER) to cytosol through the ER-associated degradation pathway. J Biol Chem. 2008;283:32352-60 pubmed publisher
Hosoi T, Sasaki M, Miyahara T, Hashimoto C, Matsuo S, Yoshii M, et al. Endoplasmic reticulum stress induces leptin resistance. Mol Pharmacol. 2008;74:1610-9 pubmed publisher
Okamura Y, Saga Y. Pofut1 is required for the proper localization of the Notch receptor during mouse development. Mech Dev. 2008;125:663-73 pubmed publisher
Ito D, Suzuki N. Molecular pathogenesis of seipin/BSCL2-related motor neuron diseases. Ann Neurol. 2007;61:237-50 pubmed
Ulmasov B, Bruno J, Woost P, Edwards J. Tissue and subcellular distribution of CLIC1. BMC Cell Biol. 2007;8:8 pubmed
Kogel D, Schomburg R, Schürmann T, Reimertz C, König H, Poppe M, et al. The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis. J Neurochem. 2003;87:248-56 pubmed
Watson L, Chan A, Berry L, Li J, Sood S, Dickhout J, et al. Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity. J Biol Chem. 2003;278:17438-47 pubmed
Culi J, Mann R. Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila. Cell. 2003;112:343-54 pubmed
Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N. ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature. 2002;419:480-3 pubmed
Kauffman K, Pridgen E, Doyle F, Dhurjati P, Robinson A. Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae. Biotechnol Prog. 2002;18:942-50 pubmed
Lhuillier L, Dryer S. Developmental regulation of neuronal K(Ca) channels by TGFbeta1: an essential role for PI3 kinase signaling and membrane insertion. J Neurophysiol. 2002;88:954-64 pubmed
Kathuria S, Sriraman R, Nath R, Sack M, Pal R, Artsaenko O, et al. Efficacy of plant-produced recombinant antibodies against HCG. Hum Reprod. 2002;17:2054-61 pubmed
Wigley W, Corboy M, Cutler T, Thibodeau P, Oldan J, Lee M, et al. A protein sequence that can encode native structure by disfavoring alternate conformations. Nat Struct Biol. 2002;9:381-8 pubmed
Toyooka K, Okamoto T, Minamikawa T. Mass transport of proform of a KDEL-tailed cysteine proteinase (SH-EP) to protein storage vacuoles by endoplasmic reticulum-derived vesicle is involved in protein mobilization in germinating seeds. J Cell Biol. 2000;148:453-64 pubmed
product information
master code :
NBP2-19019
SKU :
NBP2-19019
product name :
AIF-1/Iba1 Antibody - Azide and BSA Free
unit size :
100 ul
description :
The AIF-1/Iba1 Antibody - Azide and BSA Free from Novus is a rabbit polyclonal antibody to AIF-1/Iba1. This antibody reacts with human,mouse,primate - macaca mulatta (rhesus macaque),rat. The AIF-1/Iba1 Antibody - Azide and BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry,Simple Western,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry Free-Floating.
target :
AIF-1/Iba1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AIF-1/Iba1. The exact sequence is proprietary.
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Primate - Macaca mulatta (Rhesus Macaque),Rat
theoretical molecular weight :
17 kDa
gene symbol :
AIF1
Antibody validation :
Orthogonal Validation
applications :
Immunohistochemistry,Simple Western,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry Free-Floating
USD :
449 USD
alt names :
AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.