product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
FXR/NR1H4 Antibody - Azide Free
catalog :
NBP2-16550
quantity :
0.1 ml
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 5
Reference
Xue C, Zeng P, Gong K, Li Q, Feng Z, Wang M, et al. Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia. Cell Rep. 2024;43:114691 pubmed publisher
Chen J, Wang R, Xiong F, Sun H, Kemper B, Li W, et al. Hammerhead-type FXR agonists induce an enhancer RNA Fincor that ameliorates nonalcoholic steatohepatitis in mice. elife. 2024;13: pubmed publisher
Wang X, Yang Y, Chen Y, Duan Y, Han J, Yang X. MEK1/2 inhibitors induce class I alcohol dehydrogenase (ADH1) expression by regulating farnesoid X receptor in hepatic cell lines and C57BL/6J mouse. Mol Biol Rep. 2022;49:5843-5852 pubmed publisher
Nie H, Deng Y, Zheng C, Pan M, Xie J, Zhang Y, et al. A network pharmacology-based approach to explore the effects of Chaihu Shugan powder on a non-alcoholic fatty liver rat model through nuclear receptors. J Cell Mol Med. 2020;24:5168-5184 pubmed publisher
Zhao Q, Liu F, Cheng Y, Xiao X, Hu D, Tang Y, et al. Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling. Mol Cell Proteomics. 2019;18:520-533 pubmed publisher
product information
master code :
NBP2-16550
SKU :
NBP2-16550
product name :
FXR/NR1H4 Antibody - Azide Free
unit size :
0.1 ml
description :
The FXR/NR1H4 Antibody - Azide Free from Novus is a rabbit polyclonal antibody to FXR/NR1H4. This antibody reacts with human,mouse,rat. The FXR/NR1H4 Antibody - Azide Free has been validated for the following applications: Simple Western,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
FXR/NR1H4
category :
Primary Antibodies
buffer :
PBS, 1% BSA, 20% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Recombinant protein encompassing a sequence within the center region of human FXR/NR1H4. The exact sequence is proprietary.
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
theoretical molecular weight :
56 kDa
gene symbol :
NR1H4
Antibody validation :
Independent Anitbodies
applications :
Simple Western,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
459 USD
alt names :
bile acid receptor, farnesoid X receptor, Farnesoid X-activated receptor, Farnesol receptor HRR-1, FXRBAR, HRR-1, HRR1MGC163445, Nuclear receptor subfamily 1 group H member 4, nuclear receptor subfamily 1, group H, member 4, Retinoid X receptor-interacting protein 14, RIP14RXR-interacting protein 14
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.