Complement Component C3aR Antibody - BSA Free | Novus Biologicals NBP2-15649 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Complement Component C3aR Antibody - BSA Free

catalog :

NBP2-15649

quantity :

0.1 ml

price :

449 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

2B5

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 21

Reference
Hu X, Feng J, Deng S, Tang J, Liao Z, Luo L, et al. Anaphylatoxins enhance Th9 cell recruitment via the CCL20-CCR6 axis in IgA nephropathy. J Nephrol. 2020;: pubmed publisher
Kim W, Zhao F, Wu R, Qin S, Nowsheen S, Huang J, et al. ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex. Nat Commun. 2019;10:5304 pubmed publisher
Cipolla E, Fisher A, Gu H, Mickler E, Agarwal M, Wilke C, et al. IL-17A deficiency mitigates bleomycin-induced complement activation during lung fibrosis. FASEB J. 2017;31:5543-5556 pubmed publisher
Gu H, Fisher A, Mickler E, Duerson F, Cummings O, Peters Golden M, et al. Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis. FASEB J. 2016;30:2336-50 pubmed publisher
Haro K, Sheth A, Scheinberg D. Dysregulation of IRP1-mediated iron metabolism causes gamma ray-specific radioresistance in leukemia cells. PLoS ONE. 2012;7:e48841 pubmed publisher
Oku T, Nakano M, Kaneko Y, Ando Y, Kenmotsu H, Itoh S, et al. Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin. J Biol Chem. 2012;287:42910-20 pubmed publisher
Ha K, Fiskus W, Rao R, Balusu R, Venkannagari S, Nalabothula N, et al. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage. Mol Cancer Ther. 2011;10:1194-206 pubmed publisher
Chen Y, Chen C, Riley D, Chen P. Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR. Cell Cycle. 2011;10:655-63 pubmed
Zuco V, Benedetti V, Zunino F. ATM- and ATR-mediated response to DNA damage induced by a novel camptothecin, ST1968. Cancer Lett. 2010;292:186-96 pubmed publisher
Cui B, Johnson S, Bullock N, Ali Osman F, Bigner D, Friedman H. Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway. Mol Pharmacol. 2009;75:1356-63 pubmed publisher
Katsuki Y, Nakada S, Yokoyama T, Imoto I, Inazawa J, Nagasawa M, et al. Caffeine yields aneuploidy through asymmetrical cell division caused by misalignment of chromosomes. Cancer Sci. 2008;99:1539-45 pubmed publisher
Kulkarni A, Das K. Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation. Am J Physiol Lung Cell Mol Physiol. 2008;294:L998-L1006 pubmed publisher
Liu X, Matsuda A, Plunkett W. Ataxia-telangiectasia and Rad3-related and DNA-dependent protein kinase cooperate in G2 checkpoint activation by the DNA strand-breaking nucleoside analogue 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine. Mol Cancer Ther. 2008;7:133-42 pubmed publisher
Manthey K, Opiyo S, Glanzer J, Dimitrova D, Elliott J, Oakley G. NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse. J Cell Sci. 2007;120:4221-9 pubmed
Liu Y, Rusinol A, Sinensky M, Wang Y, Zou Y. DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A. J Cell Sci. 2006;119:4644-9 pubmed
Wu X, Shell S, Liu Y, Zou Y. ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation. Oncogene. 2007;26:757-64 pubmed
Tyagi A, Singh R, Agarwal C, Agarwal R. Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2. Carcinogenesis. 2006;27:2269-80 pubmed
Wu X, Shell S, Yang Z, Zou Y. Phosphorylation of nucleotide excision repair factor xeroderma pigmentosum group A by ataxia telangiectasia mutated and Rad3-related-dependent checkpoint pathway promotes cell survival in response to UV irradiation. Cancer Res. 2006;66:2997-3005 pubmed
Gibson S, Bindra R, Glazer P. Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner. Cancer Res. 2005;65:10734-41 pubmed
Horton J, Stefanick D, Naron J, Kedar P, Wilson S. Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure. J Biol Chem. 2005;280:15773-85 pubmed
Li J, Stern D. Regulation of CHK2 by DNA-dependent protein kinase. J Biol Chem. 2005;280:12041-50 pubmed

product information

master code :

NBP2-15649

SKU :

NBP2-15649

product name :

Complement Component C3aR Antibody - BSA Free

unit size :

0.1 ml

description :

The Complement Component C3aR Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Complement Component C3aR. This antibody reacts with human,mouse,rat. The Complement Component C3aR Antibody - BSA Free has been validated for the following applications: Western Blot,Immunoblotting,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

Complement Component C3aR

category :

Primary Antibodies

buffer :

PBS (pH 7), 20% Glycerol

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Recombinant protein encompassing a sequence within the center region of human Complement Component C3aR 1. The exact sequence is proprietary.

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

theoretical molecular weight :

54 kDa

gene symbol :

C3AR1

Antibody validation :

Knockout/Knockdown

accessionNumbers :

Q16581

applications :

Western Blot,Immunoblotting,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen

USD :

449 USD

alt names :

AZ3B, AZ3BC3a anaphylatoxin chemotactic receptor, C3a-R, C3AR, C3AR1, C3ARcomplement component 3 receptor 1, C3R1, complement component 3a receptor 1, Complement Component C3a R, Complement Component C3aR, HNFAG09

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage