MUC5AC Antibody (45M1) | Novus Biologicals NBP2-15196-0.1mg product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

MUC5AC Antibody (45M1)

catalog :

NBP2-15196-0.1mg

quantity :

0.1 mg (also 20 ug)

price :

419 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

45M1

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, dot blot

more info or order :

Novus Biologicals product webpage

citations: 25

Reference
Tao X, Li J, He J, Jiang Y, Liu C, Cao W, et al. Pinellia ternata (Thunb.) Breit. attenuates the allergic airway inflammation of cold asthma via inhibiting the activation of TLR4-medicated NF-kB and NLRP3 signaling pathway. J Ethnopharmacol. 2023;315:116720 pubmed publisher
Turner M, Cox K, Liu S, Neel N, Amirfakhri S, Nishino H, et al. Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer. Curr Issues Mol Biol. 2023;45:3347-3358 pubmed publisher
Jung M, Song H, Jo K, Lee A, Hwang Y, Ji K, et al. Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway. Biomed Pharmacother. 2023;161:114482 pubmed publisher
Bu M, Li M, Feng M, Wang J, Sun L. Poly(I:C) Exacerbates Airway Goblet Cell Hyperplasia and Lung Inflammation in HDM-Exposed Balb/C Mice by YAP/FOXM1 Pathway. Int Arch Allergy Immunol. 2023;:1-13 pubmed publisher
Koh K, Bonser L, Eckalbar W, Yizhar Barnea O, Shen J, Zeng X, et al. Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma. Cell Genom. 2023;3:100229 pubmed publisher
Xu K, Liu X, Zhang H, Zhu X, Zhang X. Tear film instability is associated with weakened colocalization between occludin and MUC5AC in scopolamine-induced dry eye disease (DED) rats. Int Ophthalmol. 2023;43:463-473 pubmed publisher
Pyun B, Jo K, Lee J, Lee A, Jung M, Hwang Y, et al. Caesalpinia sappan Linn. Ameliorates Allergic Nasal Inflammation by Upregulating the Keap1/Nrf2/HO-1 Pathway in an Allergic Rhinitis Mouse Model and Nasal Epithelial Cells. Antioxidants (Basel). 2022;11: pubmed publisher
Ueda Y, Mogami H, Kawamura Y, Takakura M, Inohaya A, Yasuda E, et al. Cervical MUC5B and MUC5AC are Barriers to Ascending Pathogens During Pregnancy. J Clin Endocrinol Metab. 2022;107:3010-3021 pubmed publisher
Tao X, Liu H, Xia J, Zeng P, Wang H, Xie Y, et al. Processed product (Pinelliae Rhizoma Praeparatum) of Pinellia ternata (Thunb.) Breit. Alleviates the allergic airway inflammation of cold phlegm via regulation of PKC/EGFR/MAPK/PI3K-AKT signaling pathway. J Ethnopharmacol. 2022;295:115449 pubmed publisher
Jung O, Tung Y, Sim E, Chen Y, Lee E, Ferrer M, et al. Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform. Biofabrication. 2022;14: pubmed publisher
Cossette C, Miller L, Ye Q, Chourey S, Reddy C, Rokach J, et al. Targeting the OXE receptor with a selective antagonist inhibits allergen-induced pulmonary inflammation in non-human primates. Br J Pharmacol. 2022;179:322-336 pubmed publisher
Wohnhaas C, Gindele J, Kiechle T, Shen Y, Leparc G, Stierstorfer B, et al. Cigarette Smoke Specifically Affects Small Airway Epithelial Cell Populations and Triggers the Expansion of Inflammatory and Squamous Differentiation Associated Basal Cells. Int J Mol Sci. 2021;22: pubmed publisher
Hicks Berthet J, Ning B, Federico A, Tilston Lunel A, Matschulat A, Ai X, et al. Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis. Cell Rep. 2021;36:109347 pubmed publisher
Diabasana Z, Perotin J, Belgacemi R, Ancel J, Mulette P, Launois C, et al. Chr15q25 Genetic Variant rs16969968 Alters Cell Differentiation in Respiratory Epithelia. Int J Mol Sci. 2021;22: pubmed publisher
Ostedgaard L, Price M, Whitworth K, Abou Alaiwa M, Fischer A, Warrier A, et al. Lack of airway submucosal glands impairs respiratory host defenses. elife. 2020;9: pubmed publisher
Ancel J, Belgacemi R, Perotin J, Diabasana Z, Dury S, Dewolf M, et al. Sonic hedgehog signalling as a potential endobronchial biomarker in COPD. Respir Res. 2020;21:207 pubmed publisher
Zarei K, Stroik M, Gansemer N, Thurman A, Ostedgaard L, Ernst S, et al. Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model. Lab Invest. 2020;100:1388-1399 pubmed publisher
Duerr J, Leitz D, Szczygiel M, Dvornikov D, Fraumann S, Kreutz C, et al. Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice. Nat Commun. 2020;11:2012 pubmed publisher
Belgacemi R, Luczka E, Ancel J, Diabasana Z, Perotin J, Germain A, et al. Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD. EBioMedicine. 2020;51:102572 pubmed publisher
Ladel S, Schlossbauer P, Flamm J, Luksch H, Mizaikoff B, Schindowski K. Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650. Pharmaceutics. 2019;11: pubmed publisher
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product information

master code :

NBP2-15196

SKU :

NBP2-15196-0.1mg

product name :

MUC5AC Antibody (45M1)

unit size :

0.1 mg (also 20 ug)

description :

The MUC5AC Antibody (45M1) from Novus is a mouse monoclonal antibody to MUC5AC. This antibody reacts with bovine (negative),chicken,feline,human,mammal,monkey,mouse,porcine,rabbit,rat. The MUC5AC Antibody (45M1) has been validated for the following applications: Multiplex Immunofluorescence,Flow Cytometry,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,IF/IHC,IHC-F,Dot Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Western Blot,Flow (Intracellular).

target :

MUC5AC

category :

Primary Antibodies

buffer :

10 mM PBS with 0.05% BSA

clonality :

Monoclonal

clone :

45M1

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

isotype :

IgG1 Kappa

purity :

Protein A or G purified

species :

Bovine (Negative),Chicken,Feline,Human,Mammal,Monkey,Mouse,Porcine,Rabbit,Rat

specificity :

This monoclonal antibody recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC)

gene symbol :

MUC5AC

accessionNumbers :

P98088

applications :

Multiplex Immunofluorescence,Flow Cytometry,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,IF/IHC,IHC-F,Dot Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Western Blot,Flow (Intracellular)

USD :

419 USD

alt names :

gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin

storage :

Store at 4C.

more info or order :

Novus Biologicals product webpage