product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SCAP Antibody - BSA Free
catalog :
NBP2-04113
quantity :
100 ul
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 4
Reference
Liu M, Lin X, Xiao L. Excess phosphate promotes SARS‑CoV‑2 N protein‑induced NLRP3 inflammasome activation via the SCAP‑SREBP2 signaling pathway. Mol Med Rep. 2024;29: pubmed publisher
Li D, Liu M, Li Z, Zheng G, Chen A, Zhao L, et al. Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice. Aging Dis. 2021;12:747-763 pubmed publisher
Muku G, Kusnadi A, Kuzu G, Tanos R, Murray I, Gowda K, et al. Selective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of SREBP-2 transcriptional activity. Lab Invest. 2020;100:250-264 pubmed publisher
Muku G, Blazanin N, Dong F, Smith P, Thiboutot D, Gowda K, et al. Selective Ah receptor ligands mediate enhanced SREBP1 proteolysis to restrict lipogenesis in sebocytes. Toxicol Sci. 2019;: pubmed publisher
product information
master code :
NBP2-04113
SKU :
NBP2-04113
product name :
SCAP Antibody - BSA Free
unit size :
100 ul
description :
The SCAP Antibody - BSA Free from Novus is a rabbit polyclonal antibody to SCAP. This antibody reacts with human,mouse. The SCAP Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Simple Western,IF/IHC,Western Blot,Immunoprecipitation.
target :
SCAP
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen recognized by this antibody maps to a region between residue 450 and 500 of human Sterol Regulatory Element Binding Protein Ceavage-Activating Protein using the numbering given in entry NP_036367.2 (GeneID 22937).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
SCAP
accessionNumbers :
NP_036367.2
applications :
Simple Western,IF/IHC,Western Blot,Immunoprecipitation
USD :
459 USD
alt names :
KIAA0199, PSEC0227, SREBF chaperone, SREBP cleavage-activating protein, sterol regulatory element binding protein cleavage-activating protein
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.