product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Slug Antibody (OTI1A6)
catalog :
NBP2-03886
quantity :
0.1 ml
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI1A6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 19
Reference
Morris H, Bamlet W, Razidlo G, Machesky L. FSCN1 and epithelial mesenchymal transformation transcription factor expression in human pancreatic intraepithelial neoplasia and ductal adenocarcinoma. Pathol Res Pract. 2023;251:154836 pubmed publisher
Liu L, Deng P, Liu S, Hong J, Xiao R, Guan P, et al. Enhancer remodeling activates NOTCH3 signaling to confer chemoresistance in advanced nasopharyngeal carcinoma. Cell Death Dis. 2023;14:513 pubmed publisher
Li S, Qian L, Chen Y, Lu H, Tsai H, Lyu H, et al. Targeting MYO1B impairs tumorigenesis via inhibiting the SNAI2/cyclin D1 signaling in esophageal squamous cell carcinoma. J Cell Physiol. 2022;237:3671-3686 pubmed publisher
Sbiera I, Kircher S, Altieri B, Fassnacht M, Kroiss M, Sbiera S. Epithelial and Mesenchymal Markers in Adrenocortical Tissues: How Mesenchymal Are Adrenocortical Tissues?. Cancers (Basel). 2021;13: pubmed publisher
Sad x142 ecki P, J xf3 x17a wicki J, Antosik P, Walentowicz Sad x142 ecka M. Expression of Selected Epithelial-Mesenchymal Transition Transcription Factors in Endometrial Cancer. Biomed Res Int. 2020;2020:4584250 pubmed publisher
Clairmont C, Sarangi P, Ponnienselvan K, Galli L, Csete I, Moreau L, et al. TRIP13 regulates DNA repair pathway choice through REV7 conformational change. Nat Cell Biol. 2020;22:87-96 pubmed publisher
Penolazzi L, Bonaccorsi G, Gafa R, Ravaioli N, Gabriele D, Bosi C, et al. SLUG/HIF1-α/miR-221 regulatory circuit in endometrial cancer. Gene. 2019;711:143938 pubmed publisher
Sadlecki P, Jóźwicki J, Antosik P, Grabiec M. Expression of selected epithelial-mesenchymal transition transcription factors in serous borderline ovarian tumors and type I ovarian cancers. Tumour Biol. 2018;40:1010428318784807 pubmed publisher
Maya Mendoza A, Moudry P, Merchut Maya J, Lee M, Strauss R, Bartek J. High speed of fork progression induces DNA replication stress and genomic instability. Nature. 2018;559:279-284 pubmed publisher
Tang Z, Yang J, Wang X, Zeng M, Wang J, Wang A, et al. Active DNA end processing in micronuclei of ovarian cancer cells. BMC Cancer. 2018;18:426 pubmed publisher
Her J, Ray C, Altshuler J, Zheng H, Bunting S. 53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress. Mol Cell Biol. 2018;38: pubmed publisher
Stepan A, Ciurea R, Drăgoescu P, Florescu M, Stepan M. Immunoexpression of transcription factors in urothelial bladder carcinomas. Rom J Morphol Embryol. 2017;58:863-869 pubmed
Munteanu C, Pirici D, Stepan A, Camen A, Margaritescu C. Maxillary calcifying epithelial odontogenic tumor with sinus and buccal vestibule extension: a case report and immunohistochemical study. Diagn Pathol. 2016;11:134 pubmed
Bass T, Luzwick J, Kavanaugh G, Carroll C, Dungrawala H, Glick G, et al. ETAA1 acts at stalled replication forks to maintain genome integrity. Nat Cell Biol. 2016;18:1185-1195 pubmed publisher
Hasegawa D, Okabe S, Okamoto K, Nakano I, Shin ya K, Seimiya H. G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells. Biochem Biophys Res Commun. 2016;471:75-81 pubmed publisher
Moudry P, Watanabe K, Wolanin K, Bartkova J, Wassing I, Watanabe S, et al. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. J Cell Biol. 2016;212:281-8 pubmed publisher
Yu Z, Huang Y, Shieh S. Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation. Nucleic Acids Res. 2016;44:1133-50 pubmed publisher
Mortusewicz O, Evers B, Helleday T. PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites. Oncogene. 2016;35:761-70 pubmed publisher
Cappellesso R, Marioni G, Crescenzi M, Giacomelli L, Guzzardo V, Mussato A, et al. The prognostic role of the epithelial-mesenchymal transition markers E-cadherin and Slug in laryngeal squamous cell carcinoma. Histopathology. 2015;67:491-500 pubmed publisher
product information
master code :
NBP2-03886
SKU :
NBP2-03886
product name :
Slug Antibody (OTI1A6)
unit size :
0.1 ml
description :
The Slug Antibody (OTI1A6) from Novus is a mouse monoclonal antibody to Slug. This antibody reacts with human,mouse,rat. The Slug Antibody (OTI1A6) has been validated for the following applications: Immunohistochemistry-Paraffin,Immunohistochemistry,IF/IHC,Flow Cytometry,Western Blot.
target :
Slug
category :
Primary Antibodies
buffer :
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
clonality :
Monoclonal
clone :
OTI1A6
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length human recombinant protein of human SNAI2 (NP_003059) produced in E.coli.
isotype :
IgG1
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
theoretical molecular weight :
29.8 kDa
gene symbol :
SNAI2
applications :
Immunohistochemistry,IF/IHC,Immunohistochemistry-Paraffin,Flow Cytometry,Western Blot
USD :
479 USD
alt names :
MGC10182, Neural crest transcription factor Slug, Protein snail homolog 2, slug homolog, zinc finger protein (chicken), SLUGH, SLUGzinc finger protein, snail 2, snail homolog 2 (Drosophila), WS2D, zinc finger protein SNAI2
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.