product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Hexokinase 2 Antibody (OTI4C5)
catalog :
NBP2-02272
quantity :
0.1 ml
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI4C5
reactivity :
human, mouse, rat, dogs
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 7
Reference
Weber Stiehl S, Taubenheim J, J xe4 rke L, R xf6 cken C, Schreiber S, Aden K, et al. Hexokinase 2 expression in apical enterocytes correlates with inflammation severity in patients with inflammatory bowel disease. BMC Med. 2024;22:490 pubmed publisher
Wang Y, Kuang Z, Xing X, Qiu Y, Zhang J, Shao D, et al. Proximal tubular FHL2, a novel downstream target of hypoxia inducible factor 1, is a protector against ischemic acute kidney injury. Cell Mol Life Sci. 2024;81:244 pubmed publisher
Vidoni C, Ferraresi A, Vallino L, Salwa A, Ha J, Seca C, et al. Glycolysis Inhibition of Autophagy Drives Malignancy in Ovarian Cancer: Exacerbation by IL-6 and Attenuation by Resveratrol. Int J Mol Sci. 2023;24: pubmed publisher
Chen C, Zhou Y, Ning X, Li S, Xue D, Wei C, et al. Directly targeting ASC by lonidamine alleviates inflammasome-driven diseases. J Neuroinflammation. 2022;19:315 pubmed publisher
Hinrichsen F, Hamm J, Westermann M, Schröder L, Shima K, Mishra N, et al. Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis. Cell Metab. 2021;33:2355-2366.e8 pubmed publisher
Yuan Q, Miao J, Yang Q, Fang L, Fang Y, Ding H, et al. Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation. Cell Death Dis. 2020;11:355 pubmed publisher
Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
product information
master code :
NBP2-02272
SKU :
NBP2-02272
product name :
Hexokinase 2 Antibody (OTI4C5)
unit size :
0.1 ml
description :
The Hexokinase 2 Antibody (OTI4C5) from Novus is a mouse monoclonal antibody to Hexokinase 2. This antibody reacts with canine,human,mouse,rat. The Hexokinase 2 Antibody (OTI4C5) has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry.
target :
Hexokinase 2
category :
Primary Antibodies
buffer :
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
clonality :
Monoclonal
clone :
OTI4C5
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length human recombinant protein of human HK2 (NP_000180) produced in HEK293T cell.
isotype :
IgG1
purity :
Immunogen affinity purified
species :
Canine,Human,Mouse,Rat
specificity :
Human Hexokinase-2 protein is 74% identical with Hexokinase-1 and our Hexokinase 2 antibody (clone 4C5) is not expected to crossreact with Hexokinase-1
theoretical molecular weight :
102.4 kDa
gene symbol :
HK2
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry
USD :
469 USD
alt names :
DKFZp686M1669, EC 2.7.1, hexokinase 2, Hexokinase type II, HKII, HXK2, muscle, Muscle form hexokinase
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.