HSPA8/HSC71/Hsc70 Antibody (1B5) | Novus Biologicals NBP1-97868 product information

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product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

HSPA8/HSC71/Hsc70 Antibody (1B5)

catalog :

NBP1-97868

quantity :

0.025 mg

price :

99 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

1B5

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 18

Reference
Burke J, Lester E, Tauber D, Parker R. RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules. J Biol Chem. 2020;295:1426-1438 pubmed publisher
Burke J, Moon S, Matheny T, Parker R. RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs. Mol Cell. 2019;75:1203-1217.e5 pubmed publisher
Al Haj L, Blackshear P, Khabar K. Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elements. Nucleic Acids Res. 2012;40:7739-52 pubmed publisher
Fabre O, Salehzada T, Lambert K, Boo Seok Y, Zhou A, Mercier J, et al. RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation. Cell Death Differ. 2012;19:1470-81 pubmed publisher
Lin R, Yu H, Chang B, Tang W, Liao C, Lin Y. Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection. J Immunol. 2009;183:8035-43 pubmed publisher
Al Ahmadi W, Al Ghamdi M, Al Haj L, Al Saif M, Khabar K. Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation. Nucleic Acids Res. 2009;37:3612-24 pubmed publisher
Li P, Itoh N, Watanabe M, Shi Y, Liu P, Yang H, et al. Association of simian virus 40 vp1 with 70-kilodalton heat shock proteins and viral tumor antigens. J Virol. 2009;83:37-46 pubmed publisher
Lu H, Sun T, Matsuzaki T, Yi X, Eswara J, Bouley R, et al. Heat shock protein 70 interacts with aquaporin-2 and regulates its trafficking. J Biol Chem. 2007;282:28721-32 pubmed
Chen S, Brown I. Neuronal expression of constitutive heat shock proteins: implications for neurodegenerative diseases. Cell Stress Chaperones. 2007;12:51-8 pubmed
Tetzlaff J, Tanzer L, Jones K. Exogenous androgen treatment delays the stress response following hamster facial nerve injury. J Neuroendocrinol. 2007;19:383-9 pubmed
Han J, Townsend H, Jha B, Paranjape J, Silverman R, Barton D. A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L. J Virol. 2007;81:5561-72 pubmed
Meinander A, Söderström T, Kaunisto A, Poukkula M, Sistonen L, Eriksson J. Fever-like hyperthermia controls T Lymphocyte persistence by inducing degradation of cellular FLIPshort. J Immunol. 2007;178:3944-53 pubmed
Suttitanamongkol S, Polanowska Grabowska R, Gear A. Heat-shock protein 90 complexes in resting and thrombin-activated platelets. Biochem Biophys Res Commun. 2002;297:129-33 pubmed
Yamano T, Murata S, Shimbara N, Tanaka N, Chiba T, Tanaka K, et al. Two distinct pathways mediated by PA28 and hsp90 in major histocompatibility complex class I antigen processing. J Exp Med. 2002;196:185-96 pubmed
Bailey C, Andriola I, Kampinga H, Merry D. Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy. Hum Mol Genet. 2002;11:515-23 pubmed
Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, et al. Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat Genet. 2002;30:181-4 pubmed
Brighty D, Jassal S. The synthetic peptide P-197 inhibits human T-cell leukemia virus type 1 envelope-mediated syncytium formation by a mechanism that is independent of Hsc70. J Virol. 2001;75:10472-8 pubmed
Sainis L, Angelidis C, Pagoulatos G, Lazaridis L. HSC70 interactions with SV40 viral proteins differ between permissive and nonpermissive mammalian cells. Cell Stress Chaperones. 2000;5:132-8 pubmed

product information

brand :

Novus

master code :

NBP1-97868

SKU :

NBP1-97868-0.025mg

product name :

HSPA8/HSC71/Hsc70 Antibody (1B5)

description :

The HSPA8/HSC71/Hsc70 Antibody (1B5) from Novus Biologicals is a rat monoclonal antibody to HSPA8/HSC71/Hsc70. This antibody reacts with human, mouse, rat, porcine, bovine, canine, chicken, guinea pig, hamster, monkey, rabbit, sheep. The HSPA8/HSC71/Hsc70 Antibody (1B5) has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Electron Microscopy.

target :

HSPA8/HSC71/Hsc70

category :

Primary Antibodies

unit size :

0.025 mg

buffer :

PBS (pH 7.2) and 50% Glycerol

clonality :

Monoclonal

clone :

1B5

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rat

immunogen :

Native hamster Hsc70 (Hsp73).

isotype :

IgG2a

purity :

Protein G purified

species :

Human, Mouse, Rat, Porcine, Bovine, Canine, Chicken, Guinea Pig, Hamster, Monkey, Rabbit, Sheep

theoretical molecular weight :

73 kDa

gene symbol :

HSPA8

catalog number base :

NBP1-97868

applications :

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Electron Microscopy

2020 USD :

2021 USD :

99 USD

alt names :

Heat shock 70 kDa protein 8, heat shock 70kD protein 8, heat shock 70kDa protein 8, heat shock cognate 71 kDa protein, heat shock cognate protein 54, heat shock cognate protein, 71-kDa, HSC54, HSC70heat shock 70kd protein 10, HSC71, HSP71, HSP73constitutive heat shock protein 70, HSPA10, LAP1, lipopolysaccharide-associated protein 1, LPS-associated protein 1, MGC131511, MGC29929, NIP71, N-myristoyltransferase inhibitor protein 71

storage :

Store at -20C. Avoid freeze-thaw cycles.