product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TLR5 Antibody (85B152.5) - BSA Free
catalog :
NBP1-97728
quantity :
0.1 mg (also 0.025 mg)
price :
399 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
85B152.5
reactivity :
human, mouse, dogs
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 45
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 7b
Lee S, Hong S, Verma V, Lee Y, Duong T, Jeong K, et al. Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer. Oncoimmunology. 2016;5:e1081328 pubmed
  • western blot; human
Li Z, Younger K, Gartenhaus R, Joseph A, Hu F, Baer M, et al. Inhibition of IRAK1/4 sensitizes T cell acute lymphoblastic leukemia to chemotherapies. J Clin Invest. 2015;125:1081-97 pubmed publisher
Kumazoe M, Takamatsu K, Horie F, Yoshitomi R, Hamagami H, Tanaka H, et al. Methylated (-)-epigallocatechin 3-O-gallate potentiates the effect of split vaccine accompanied with upregulation of Toll-like receptor 5. Sci Rep. 2021;11:23101 pubmed publisher
Mahgoub M, Paiano J, Bruno M, Wu W, Pathuri S, Zhang X, et al. Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice. elife. 2020;9: pubmed publisher
Hoang T, Jung J, Kim J. All-Trans Retinoic Acid Enhances Bacterial Flagellin-Stimulated Proinflammatory Responses in Human Monocyte THP-1 Cells by Upregulating CD14. Biomed Res Int. 2019;2019:8059312 pubmed publisher
Ruffenach G, Umar S, Vaillancourt M, Hong J, Cao N, Sarji S, et al. Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis. EMBO Mol Med. 2019;11:e10061 pubmed publisher
Graf K, Last A, Gratz R, Allert S, Linde S, Westermann M, et al. Keeping Candida commensal: how lactobacilli antagonize pathogenicity of Candida albicans in an in vitro gut model. Dis Model Mech. 2019;12: pubmed publisher
Jaworski S, Strojny B, Sawosz E, Wierzbicki M, Grodzik M, Kutwin M, et al. Degradation of Mitochondria and Oxidative Stress as the Main Mechanism of Toxicity of Pristine Graphene on U87 Glioblastoma Cells and Tumors and HS-5 Cells. Int J Mol Sci. 2019;20: pubmed publisher
Warkocki Z, Krawczyk P, Adamska D, Bijata K, Garcia Perez J, Dziembowski A. Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. Cell. 2018;174:1537-1548.e29 pubmed publisher
Konopaske G, Balu D, Presti K, Chan G, Benes F, Coyle J. Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia. Schizophr Res. 2018;201:270-277 pubmed publisher
Wang C, Lee Y, Lin Y, Chung W, Tzeng Y, Lee C. Ovatodiolide suppresses allergic airway inflammation and hyperresponsiveness in a murine model of asthma. Eur J Pharmacol. 2017;812:9-17 pubmed publisher
Skjørringe T, Amstrup Pedersen P, Salling Thorborg S, Nissen P, Gourdon P, Birk Møller L. Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease. Sci Rep. 2017;7:757 pubmed publisher
Lora V, Clemente Napimoga J, Abdalla H, Macedo C, Canales G, Barbosa C. Botulinum toxin type A reduces inflammatory hypernociception induced by arthritis in the temporomadibular joint of rats. Toxicon. 2017;129:52-57 pubmed publisher
Kalisiak K, Kulinski T, Tomecki R, Cysewski D, Pietras Z, Chlebowski A, et al. A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans. Nucleic Acids Res. 2017;45:2068-2080 pubmed publisher
Majali Martinez A, Velicky P, Pollheimer J, Knöfler M, Yung H, Burton G, et al. Endothelin-1 down-regulates matrix metalloproteinase 14 and 15 expression in human first trimester trophoblasts via endothelin receptor type B. Hum Reprod. 2017;32:46-54 pubmed
Duprey Díaz M, Blagburn J, Blanco R. Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System after Optic Nerve Injury. PLoS ONE. 2016;11:e0162626 pubmed publisher
Labroo P, SHEA J, Sant H, Gale B, Agarwal J. Effect Of combining FK506 and neurotrophins on neurite branching and elongation. Muscle Nerve. 2017;55:570-581 pubmed publisher
Deng H, Shi Y, Yang Y, Ahmeti K, Miller N, Huang C, et al. Identification of TMEM230 mutations in familial Parkinson's disease. Nat Genet. 2016;48:733-9 pubmed publisher
Mastorci K, Muraro E, Pasini E, Furlan C, Sigalotti L, Cinco M, et al. Toll-Like Receptor 1/2 and 5 Ligands Enhance the Expression of Cyclin D1 and D3 and Induce Proliferation in Mantle Cell Lymphoma. PLoS ONE. 2016;11:e0153823 pubmed publisher
Moreira M, Costa Pereira C, Alves M, Marteleto B, Ribeiro V, Peruhype Magalhães V, et al. Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes. Vet Parasitol. 2016;220:33-45 pubmed publisher
Iorga A, Li J, Sharma S, Umar S, Bopassa J, Nadadur R, et al. Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. J Am Heart Assoc. 2016;5: pubmed publisher
Kato K, Lillehoj E, Kim K. Pseudomonas aeruginosa stimulates tyrosine phosphorylation of and TLR5 association with the MUC1 cytoplasmic tail through EGFR activation. Inflamm Res. 2016;65:225-33 pubmed publisher
Lam C, Golas G, Davids M, Huizing M, Kane M, Krasnewich D, et al. Expanding the clinical and molecular characteristics of PIGT-CDG, a disorder of glycosylphosphatidylinositol anchors. Mol Genet Metab. 2015;115:128-140 pubmed publisher
Jaworski S, Sawosz E, Kutwin M, Wierzbicki M, Hinzmann M, Grodzik M, et al. In vitro and in vivo effects of graphene oxide and reduced graphene oxide on glioblastoma. Int J Nanomedicine. 2015;10:1585-96 pubmed publisher
Mishra A, Brown A, Yao X, Yang S, Park S, Liu C, et al. Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase. Nat Commun. 2015;6:6224 pubmed publisher
Bens M, Vimont S, Ben Mkaddem S, Chassin C, Goujon J, Balloy V, et al. Flagellin/TLR5 signalling activates renal collecting duct cells and facilitates invasion and cellular translocation of uropathogenic Escherichia coli. Cell Microbiol. 2014;16:1503-17 pubmed publisher
Sawitzki B, Brunstein C, Meisel C, Schumann J, Vogt K, Appelt C, et al. Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression. Biol Blood Marrow Transplant. 2014;20:173-82 pubmed publisher
Abdi J, Mutis T, Garssen J, Redegeld F. Characterization of the Toll-like receptor expression profile in human multiple myeloma cells. PLoS ONE. 2013;8:e60671 pubmed publisher
Feng T, Cong Y, Alexander K, Elson C. Regulation of Toll-like receptor 5 gene expression and function on mucosal dendritic cells. PLoS ONE. 2012;7:e35918 pubmed publisher
van den Berk L, Jansen B, Siebers Vermeulen K, Netea M, Latuhihin T, Bergevoet S, et al. Toll-like receptor triggering in cord blood mesenchymal stem cells. J Cell Mol Med. 2009;13:3415-26 pubmed publisher
Hafez M, Hayes K, Goldrick M, Grencis R, Roberts I. The K5 capsule of Escherichia coli strain Nissle 1917 is important in stimulating expression of Toll-like receptor 5, CD14, MyD88, and TRIF together with the induction of interleukin-8 expression via the mitogen-activated protein kinase pathway in ep. Infect Immun. 2010;78:2153-62 pubmed publisher
Rydberg C, Mansson A, Uddman R, Riesbeck K, Cardell L. Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas. Immunology. 2009;128:e600-11 pubmed publisher
Wu H, Wang H, Xiong W, Chen S, Tang H, Han D. Expression patterns and functions of toll-like receptors in mouse sertoli cells. Endocrinology. 2008;149:4402-12 pubmed publisher
Burgener I, Jungi T. Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol. 2008;124:184-91 pubmed publisher
Pegu A, Qin S, Fallert Junecko B, Nisato R, Pepper M, Reinhart T. Human lymphatic endothelial cells express multiple functional TLRs. J Immunol. 2008;180:3399-405 pubmed
He B, Xu W, Santini P, Polydorides A, Chiu A, Estrella J, et al. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity. 2007;26:812-26 pubmed
Wong C, Cheung P, Ip W, Lam C. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007;37:85-96 pubmed
Riccioli A, Starace D, Galli R, Fuso A, Scarpa S, Palombi F, et al. Sertoli cells initiate testicular innate immune responses through TLR activation. J Immunol. 2006;177:7122-30 pubmed
LeBouder E, Rey Nores J, Raby A, Affolter M, Vidal K, Thornton C, et al. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk. J Immunol. 2006;176:3742-52 pubmed
Mansson A, Adner M, Cardell L. Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Respir Res. 2006;7:36 pubmed
Crellin N, Garcia R, Hadisfar O, Allan S, Steiner T, Levings M. Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J Immunol. 2005;175:8051-9 pubmed
Francois S, El Benna J, Dang P, Pedruzzi E, Gougerot Pocidalo M, Elbim C. Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad. J Immunol. 2005;174:3633-42 pubmed
Chuang T, Ulevitch R. Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells. Biochim Biophys Acta. 2001;1518:157-61 pubmed
Muzio M, Natoli G, Saccani S, Levrero M, Mantovani A. The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6). J Exp Med. 1998;187:2097-101 pubmed
Medzhitov R, Janeway C. Innate immunity: the virtues of a nonclonal system of recognition. Cell. 1997;91:295-8 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NBP1-97728
SKU :
NBP1-97728
product name :
TLR5 Antibody (85B152.5) - BSA Free
description :
The TLR5 Antibody (85B152.5) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to TLR5. This antibody reacts with canine,human,mouse. The TLR5 Antibody (85B152.5) - BSA Free has been validated for the following applications: Immunohistochemistry,Flow (Intracellular),Flow Cytometry Control,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Flow (Cell Surface).
target :
TLR5
unit size :
0.1 mg (also 0.025 mg)
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
85B152.5
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
This antibody was developed against KLH-conjugated synthetic peptide corresponding to a portion of human TLR5. It will cross-react with mouse TLR5 (NP_003259).
isotype :
IgG2a
purity :
Protein G purified
species :
Canine,Human,Mouse
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
theoretical molecular weight :
100 kDa
gene symbol :
TLR5
applications :
Immunohistochemistry,Flow (Intracellular),Flow Cytometry Control,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Flow (Cell Surface)
USD :
399
USD 2025 :
399 USD
alt names :
MGC126430, MGC126431, SLEB1FLJ10052, TIL3Toll/interleukin-1 receptor-like protein 3, toll-like receptor 5
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.