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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
NLRP3/NALP3 Antibody (Nalpy3-b) - BSA Free
catalog :
NBP1-97601
quantity :
0.05 mg (also 0.025 mg)
price :
349 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Nalpy3-b
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5h
Li D, Liu M, Li Z, Zheng G, Chen A, Zhao L, et al. Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice. Aging Dis. 2021;12:747-763 pubmed publisher
Liu M, Lin X, Xiao L. Excess phosphate promotes SARS‑CoV‑2 N protein‑induced NLRP3 inflammasome activation via the SCAP‑SREBP2 signaling pathway. Mol Med Rep. 2024;29: pubmed publisher
Ivarsson J, Ferrara F, Vallese A, Guiotto A, Colella S, Pecorelli A, et al. Comparison of Pollutant Effects on Cutaneous Inflammasomes Activation. Int J Mol Sci. 2023;24: pubmed publisher
Sun C, Diao Q, Lu J, Zhang Z, Wu D, Wang X, et al. Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence. J Cell Physiol. 2019;234:5926-5939 pubmed publisher
Gao F, Fish B, Szabo A, Schock A, Narayanan J, Jacobs E, et al. Enhanced survival from radiation pneumonitis by combined irradiation to the skin. Int J Radiat Biol. 2014;90:753-61 pubmed publisher
Farkas D, Kraskauskas D, Drake J, Alhussaini A, Kraskauskiene V, Bogaard H, et al. CXCR4 inhibition ameliorates severe obliterative pulmonary hypertension and accumulation of C-kit? cells in rats. PLoS ONE. 2014;9:e89810 pubmed publisher
Masaka T, Iijima K, Endo H, Asanuma K, Ara N, Ishiyama F, et al. Gender differences in oesophageal mucosal injury in a reflux oesophagitis model of rats. Gut. 2013;62:6-14 pubmed publisher
LĂȘ B, Khorsi Cauet H, Bach V, Gay QuĂ©heillard J. Mast cells mediate Pseudomonas aeruginosa lipopolysaccharide-induced lung inflammation in rat. Eur J Clin Microbiol Infect Dis. 2012;31:1983-90 pubmed publisher
Shimada R, Nakao K, Furutani R, Kibayashi K. A rat model of changes in dural mast cells and brain histamine receptor H3 expression following traumatic brain injury. J Clin Neurosci. 2012;19:447-51 pubmed publisher
Shio M, Tiemi Shio M, Eisenbarth S, Savaria M, Vinet A, Bellemare M, et al. Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. PLoS Pathog. 2009;5:e1000559 pubmed publisher
Kummer J, Broekhuizen R, Everett H, Agostini L, Kuijk L, Martinon F, et al. Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J Histochem Cytochem. 2007;55:443-52 pubmed
Sato Y, Harada K, Kizawa K, Sanzen T, Furubo S, Yasoshima M, et al. Activation of the MEK5/ERK5 cascade is responsible for biliary dysgenesis in a rat model of Caroli's disease. Am J Pathol. 2005;166:49-60 pubmed
Haase M, Klawitter A, Baretton G. IkappaBgamma is expressed in mast cells. Virchows Arch. 2004;445:515-20 pubmed
Agostini L, Martinon F, Burns K, McDermott M, Hawkins P, Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity. 2004;20:319-25 pubmed
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NBP1-97601
SKU :
NBP1-97601
product name :
NLRP3/NALP3 Antibody (Nalpy3-b) - BSA Free
description :
The NLRP3/NALP3 Antibody (Nalpy3-b) - BSA Free from Novus Biologicals is a mouse monoclonal antibody to NLRP3/NALP3. This antibody reacts with human. The NLRP3/NALP3 Antibody (Nalpy3-b) - BSA Free has been validated for the following applications: Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry,Western Blot.
target :
NLRP3/NALP3
unit size :
0.05 mg (also 0.025 mg)
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
Nalpy3-b
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant human NLRP3/NALP3 Antibody (Nalpy3-b) (NACHT-, LRR- and PYD-containing protein 3) (pyrin domain).
isotype :
IgG1
purity :
Protein G purified
species :
Human
specificity :
Recognizes human NLRP3/NALP3
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
gene symbol :
NLRP3
applications :
Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry,Western Blot
USD :
339
USD 2025 :
349 USD
alt names :
AII, AII/AVP, Angiotensin/vasopressin receptor AII/AVP-like, AVP, C1orf7, Caterpiller protein 1.1, CLR1.1, Cold autoinflammatory syndrome 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, Familial cold autoinflammatory syndrome, FCU, Leucine-rich repeat-, and PYD-containing protein 3, Muckle-Wells syndrome, MWS, NACHT, LRR and PYD containing protein 3, NACHT, LRR and PYD domains-containing protein 3, NALP3, NLR family, pyrin domain containing 3, NLRP3, Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 3, PYPAF1, PYRIN-containing APAF1-like protein 1
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.