Hsp47 Antibody (M16.10A1) | Novus Biologicals NBP1-97491 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Hsp47 Antibody (M16.10A1)

catalog :

NBP1-97491

quantity :

0.025 mg

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M16.10A1

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 28

Reference
Hreha T, Collins C, Daugherty A, Twentyman J, Paluri N, Hunstad D. TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis. Physiol Rep. 2020;8:e14401 pubmed publisher
Yang L, Han B, Zhang M, Wang Y, Tao K, Zhu M, et al. Activation of BK Channels Prevents Hepatic Stellate Cell Activation and Liver Fibrosis Through the Suppression of TGFβ1/SMAD3 and JAK/STAT3 Profibrotic Signaling Pathways. Front Pharmacol. 2020;11:165 pubmed publisher
Li W, Zhang X, Wu F, Zhou Y, Bao Z, Li H, et al. Gastric cancer-derived mesenchymal stromal cells trigger M2 macrophage polarization that promotes metastasis and EMT in gastric cancer. Cell Death Dis. 2019;10:918 pubmed publisher
Grüneboom A, Hawwari I, Weidner D, Culemann S, Müller S, Henneberg S, et al. A network of trans-cortical capillaries as mainstay for blood circulation in long bones. Nat Metab. 2019;1:236-250 pubmed publisher
Ruffenach G, Umar S, Vaillancourt M, Hong J, Cao N, Sarji S, et al. Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis. EMBO Mol Med. 2019;11:e10061 pubmed publisher
Khalil H, Kanisicak O, Vagnozzi R, Johansen A, Maliken B, Prasad V, et al. Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart. JCI Insight. 2019;4:e128722 pubmed publisher
Tan T, Hu H, Wang H, Li J, Wang Z, Wang J, et al. Bioinspired lipoproteins-mediated photothermia remodels tumor stroma to improve cancer cell accessibility of second nanoparticles. Nat Commun. 2019;10:3322 pubmed publisher
Kangawa A, Nishimura T, Nishimura T, Otake M, Enya S, Yoshida T, et al. Spontaneous Age-Related Histopathological Changes in Microminipigs. Toxicol Pathol. 2019;47:817-832 pubmed publisher
Chen Y, Gonzalez M, Burman B, Zhao X, Anwar T, Tran M, et al. Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer. Cell Rep. 2019;27:3916-3926.e5 pubmed publisher
An S, Raju I, Surenkhuu B, Kwon J, Gulati S, Karaman M, et al. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Ocul Surf. 2019;: pubmed publisher
Chu S, Chou C, Huang H, Yen M, Hong H, Chao P, et al. Mechanical stretch induces hair regeneration through the alternative activation of macrophages. Nat Commun. 2019;10:1524 pubmed publisher
Bloodworth N, Clark C, West J, Snider J, Gaskill C, Shay S, et al. Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening via Serotonin 2B Receptor Dependent Mechanism. Circ Res. 2018;123:e51-e64 pubmed publisher
Bowler M, Bersi M, Ryzhova L, Jerrell R, Parekh A, Merryman W. Cadherin-11 as a regulator of valve myofibroblast mechanobiology. Am J Physiol Heart Circ Physiol. 2018;315:H1614-H1626 pubmed publisher
Hirata Y, Aoki H, Shojima T, Takagi K, Takaseya T, Akasu K, et al. Activation of the AKT Pathway in the Ascending Aorta With Bicuspid Aortic Valve. Circ J. 2018;82:2485-2492 pubmed publisher
Canuto M, Yacoub C, Trindade M, Avancini J, Pagliari C, Sotto M. Histoid leprosy: clinical and histopathological analysis of patients in follow-up in University Clinical Hospital of endemic country. Int J Dermatol. 2018;57:707-712 pubmed publisher
Chen Y, Wu Z, Yuan B, Dong Y, Zhang L, Zeng Z. MicroRNA-146a-5p attenuates irradiation-induced and LPS-induced hepatic stellate cell activation and hepatocyte apoptosis through inhibition of TLR4 pathway. Cell Death Dis. 2018;9:22 pubmed publisher
Guzy R, Li L, Smith C, Dorry S, Koo H, Chen L, et al. Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling. J Biol Chem. 2017;292:10364-10378 pubmed publisher
El Agha E, Moiseenko A, Kheirollahi V, De Langhe S, Crnkovic S, Kwapiszewska G, et al. Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis. Cell Stem Cell. 2017;20:261-273.e3 pubmed publisher
Zhu L, Zhao S, Liu S, Liu Q, Li F, Hao J. PTEN Regulates Renal Extracellular Matrix Deposit via Increased CTGF in Diabetes Mellitus. J Cell Biochem. 2016;117:1187-98 pubmed publisher
Kurashige T, Abe K, Furusu A, Miyazaki M, Obata Y, Xia Z, et al. Renoprotective effect of azelnidipine in rats. Biol Pharm Bull. 2008;31:2237-44 pubmed
Li D, Guang W, Abuzeid W, Roy S, Gao G, Sauk J, et al. Novel adenoviral gene delivery system targeted against head and neck cancer. Laryngoscope. 2008;118:650-8 pubmed publisher
Ogawa Y, Razzaque M, Kameyama K, Hasegawa G, Shimmura S, Kawai M, et al. Role of heat shock protein 47, a collagen-binding chaperone, in lacrimal gland pathology in patients with cGVHD. Invest Ophthalmol Vis Sci. 2007;48:1079-86 pubmed
Chai Q, Krag S, Chai S, Ledet T, Wogensen L. Localisation and phenotypical characterisation of collagen-producing cells in TGF-beta 1-induced renal interstitial fibrosis. Histochem Cell Biol. 2003;119:267-80 pubmed
Yokota S, Kubota H, Matsuoka Y, Naitoh M, Hirata D, Minota S, et al. Prevalence of HSP47 antigen and autoantibodies to HSP47 in the sera of patients with mixed connective tissue disease. Biochem Biophys Res Commun. 2003;303:413-8 pubmed
Rocnik E, van der Veer E, Cao H, Hegele R, Pickering J. Functional linkage between the endoplasmic reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells. J Biol Chem. 2002;277:38571-8 pubmed
Tasab M, Jenkinson L, Bulleid N. Sequence-specific recognition of collagen triple helices by the collagen-specific molecular chaperone HSP47. J Biol Chem. 2002;277:35007-12 pubmed
Rocnik E, Saward L, Pickering J. HSP47 expression by smooth muscle cells is increased during arterial development and lesion formation and is inhibited by fibrillar collagen. Arterioscler Thromb Vasc Biol. 2001;21:40-6 pubmed
Suzuki T, Kimura M, Asano M, Fujigaki Y, Hishida A. Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat. Am J Pathol. 2001;158:75-85 pubmed

product information

brand :

Novus

master code :

NBP1-97491

SKU :

NBP1-97491-0.025mg

product name :

Hsp47 Antibody (M16.10A1)

description :

The Hsp47 Antibody (M16.10A1) from Novus Biologicals is a mouse monoclonal antibody to Hsp47. This antibody reacts with human, mouse, rat, porcine, bovine, canine, chicken, guinea pig, hamster, monkey, rabbit, sheep. The Hsp47 Antibody (M16.10A1) has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated.

target :

Hsp47

category :

Primary Antibodies

unit size :

0.025 mg

buffer :

PBS (pH 7.2) and 50% Glycerol

clonality :

Monoclonal

clone :

M16.10A1

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Native rat HSP47.

isotype :

IgG2b

purity :

Protein G purified

species :

Human, Mouse, Rat, Porcine, Bovine, Canine, Chicken, Guinea Pig, Hamster, Monkey, Rabbit, Sheep

gene symbol :

SERPINH1

catalog number base :

NBP1-97491

applications :

Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated

2020 USD :

2021 USD :

149 USD

alt names :

(collagen binding protein 1), Arsenic-transactivated protein 3, AsTP3, CBP1, CBP2RA-A47, Cell proliferation-inducing gene 14 protein, Collagen-binding protein, colligen, Colligin, colligin-1, colligin-2, gp46, HSP47serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1), member 2, member 2, (collagen-binding protein 2), PPROM, proliferation-inducing gene 14, rheumatoid arthritis antigen A-47,47 kDa heat shock protein, Rheumatoid arthritis-related antigen RA-A47, serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), serpin H1, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, SERPINH2colligin

storage :

Store at -20C. Avoid freeze-thaw cycles.