Hsp47 Antibody (M16.10A1) | Novus Biologicals NBP1-97491-0.05mg product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Hsp47 Antibody (M16.10A1)

catalog :

NBP1-97491-0.05mg

quantity :

0.05 mg (also 0.025 mg, 0.2 mg)

price :

349 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M16.10A1

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 18

Reference
Gan C, Yaqoob U, Lu J, Xie M, Anwar A, Jalan Sakrikar N, et al. Liver sinusoidal endothelial cells contribute to portal hypertension through collagen type IV-driven sinusoidal remodeling. JCI Insight. 2024;9: pubmed publisher
Han X, Gong N, Xue L, Billingsley M, El Mayta R, Shepherd S, et al. Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis. Nat Commun. 2023;14:75 pubmed publisher
Sano M, Hirakawa S, Sasaki T, Inuzuka K, Katahashi K, Kayama T, et al. Role of Subcutaneous Adipose Tissues in the Pathophysiology of Secondary Lymphedema. Lymphat Res Biol. 2022;20:593-599 pubmed publisher
Sun X, Chen C, Liu H, Tang S. High glucose induces HSP47 expression and promotes the secretion of inflammatory factors through the IRE1α/XBP1/HIF-1α pathway in retinal Müller cells. Exp Ther Med. 2021;22:1411 pubmed publisher
Marom R, Burrage L, Venditti R, Clément A, Blanco Sanchez B, Jain M, et al. COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay. Am J Hum Genet. 2021;108:1710-1724 pubmed publisher
Kim S, Kim B, Kim J, Kim D, Lee S, Lee D, et al. L-myc Gene Expression in Canine Fetal Fibroblasts Promotes Self-Renewal Capacity but Not Tumor Formation. Cells. 2021;10: pubmed publisher
Strack E, Rolfe P, Fink A, Bankov K, Schmid T, Solbach C, et al. Identification of tumor-associated macrophage subsets that are associated with breast cancer prognosis. Clin Transl Med. 2020;10:e239 pubmed publisher
Khalil H, Kanisicak O, Vagnozzi R, Johansen A, Maliken B, Prasad V, et al. Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart. JCI Insight. 2019;4:e128722 pubmed publisher
Chu S, Chou C, Huang H, Yen M, Hong H, Chao P, et al. Mechanical stretch induces hair regeneration through the alternative activation of macrophages. Nat Commun. 2019;10:1524 pubmed publisher
Kurashige T, Abe K, Furusu A, Miyazaki M, Obata Y, Xia Z, et al. Renoprotective effect of azelnidipine in rats. Biol Pharm Bull. 2008;31:2237-44 pubmed
Li D, Guang W, Abuzeid W, Roy S, Gao G, Sauk J, et al. Novel adenoviral gene delivery system targeted against head and neck cancer. Laryngoscope. 2008;118:650-8 pubmed publisher
Ogawa Y, Razzaque M, Kameyama K, Hasegawa G, Shimmura S, Kawai M, et al. Role of heat shock protein 47, a collagen-binding chaperone, in lacrimal gland pathology in patients with cGVHD. Invest Ophthalmol Vis Sci. 2007;48:1079-86 pubmed
Chai Q, Krag S, Chai S, Ledet T, Wogensen L. Localisation and phenotypical characterisation of collagen-producing cells in TGF-beta 1-induced renal interstitial fibrosis. Histochem Cell Biol. 2003;119:267-80 pubmed
Yokota S, Kubota H, Matsuoka Y, Naitoh M, Hirata D, Minota S, et al. Prevalence of HSP47 antigen and autoantibodies to HSP47 in the sera of patients with mixed connective tissue disease. Biochem Biophys Res Commun. 2003;303:413-8 pubmed
Rocnik E, van der Veer E, Cao H, Hegele R, Pickering J. Functional linkage between the endoplasmic reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells. J Biol Chem. 2002;277:38571-8 pubmed
Tasab M, Jenkinson L, Bulleid N. Sequence-specific recognition of collagen triple helices by the collagen-specific molecular chaperone HSP47. J Biol Chem. 2002;277:35007-12 pubmed
Rocnik E, Saward L, Pickering J. HSP47 expression by smooth muscle cells is increased during arterial development and lesion formation and is inhibited by fibrillar collagen. Arterioscler Thromb Vasc Biol. 2001;21:40-6 pubmed
Suzuki T, Kimura M, Asano M, Fujigaki Y, Hishida A. Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat. Am J Pathol. 2001;158:75-85 pubmed

product information

brand :

Novus

master code :

NBP1-97491

SKU :

NBP1-97491-0.05mg

product name :

Hsp47 Antibody (M16.10A1)

unit size :

0.05 mg (also 0.025 mg, 0.2 mg)

seo description :

The Hsp47 Antibody (M16.10A1) - BSA Free from Novus is a mouse monoclonal antibody to Hsp47. This antibody reacts with bovine,canine,chicken,guinea pig,hamster,human,monkey,mouse,porcine,rabbit,rat,sheep. The Hsp47 Antibody (M16.10A1) - BSA Free has been validated for the following applications: IF/IHC,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Frozen,Simple Western,Knockdown Validated.

target :

Hsp47

category :

Primary Antibodies

buffer :

PBS (pH 7.2) and 50% Glycerol

clonality :

Monoclonal

clone :

M16.10A1

concentration :

1.0 mg/ml

conjugate :

Unconjugated

dilution :

Western Blot 1:1000, Simple Western 1:100, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/ Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:50, Immunohistochemistry-Frozen 1:10-1:500, Knockdown Validated

host :

Mouse

immunogen :

Native rat HSP47.

isotype :

IgG2b

purity :

Protein G purified

species :

Bovine,Canine,Chicken,Guinea Pig,Hamster,Human,Monkey,Mouse,Porcine,Rabbit,Rat,Sheep

gene symbol :

SERPINH1

applications :

Immunohistochemistry,Immunohistochemistry-Frozen,Simple Western,Knockdown Validated,IF/IHC,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence

USD :

349 USD

alt names :

(collagen binding protein 1), Arsenic-transactivated protein 3, AsTP3, CBP1, CBP2RA-A47, Cell proliferation-inducing gene 14 protein, Collagen-binding protein, colligen, Colligin, colligin-1, colligin-2, gp46, HSP47serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1), member 2, member 2, (collagen-binding protein 2), PPROM, proliferation-inducing gene 14, rheumatoid arthritis antigen A-47,47 kDa heat shock protein, Rheumatoid arthritis-related antigen RA-A47, serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), serpin H1, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, SERPINH2colligin

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage