KDEL Antibody (10C3) | Novus Biologicals NBP1-97469-0.1mg product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

KDEL Antibody (10C3)

catalog :

NBP1-97469-0.1mg

quantity :

0.1 mg (also 0.025 mg)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10C3

reactivity :

human, mouse, rat, chicken

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 27

Reference
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Wei X, Lu Y, Lin L, Zhang C, Chen X, Wang S, et al. Proteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its role in glycosylphosphatidylinositol-anchored protein biogenesis. Nat Commun. 2024;15:659 pubmed publisher
Wu S, Shen C, Wei X, Zhang X, Wang S, Chen X, et al. The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes. Nat Commun. 2023;14:3132 pubmed publisher
Jacquier A, Risson V, Simonet T, Roussange F, Lacoste N, Ribault S, et al. Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons. Acta Neuropathol. 2022;144:707-731 pubmed publisher
Muroi H, Hori K, Tokutake Y, Hakamata Y, Kawabata F, Toyomizu M, et al. Oleuropein suppresses mitochondrial reactive oxygen species generation possibly via an activation of transient receptor potential V1 and sirtuin-1 in cultured chicken muscle cells. Anim Sci J. 2022;93:e13677 pubmed publisher
Maddineni P, Kasetti R, Kodati B, Yacoub S, Zode G. Sodium 4-Phenylbutyrate Reduces Ocular Hypertension by Degrading Extracellular Matrix Deposition via Activation of MMP9. Int J Mol Sci. 2021;22: pubmed publisher
Coudert L, Osseni A, Gangloff Y, Schaeffer L, Leblanc P. The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways. BMC Biol. 2021;19:153 pubmed publisher
Wang G, Xu J, Zhao J, Yin W, Liu D, Chen W, et al. Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice. Nat Commun. 2020;11:220 pubmed publisher
Chang M, Brown M, Liu Y, Gainullin V, Harris P, Romero M, et al. Cl- and H+ coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl-/H+ exchanger ClC-5. J Biol Chem. 2020;295:1464-1473 pubmed publisher
Kalainayakan S, Ghosh P, Dey S, FitzGerald K, Sohoni S, Konduri P, et al. Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression. Sci Rep. 2019;9:1405 pubmed publisher
Hao Y, Chow A, Yip W, Li C, Wan T, Tong B, et al. G protein-coupled estrogen receptor inhibits the P2Y receptor-mediated Ca(2+) signaling pathway in human airway epithelia. Pflugers Arch. 2016;468:1489-503 pubmed publisher
Kilaparty S, Agarwal R, Singh P, Kannan K, Ali N. Endoplasmic reticulum stress-induced apoptosis accompanies enhanced expression of multiple inositol polyphosphate phosphatase 1 (Minpp1): a possible role for Minpp1 in cellular stress response. Cell Stress Chaperones. 2016;21:593-608 pubmed publisher
Putz U, Howitt J, Lackovic J, Foot N, Kumar S, Silke J, et al. Nedd4 family-interacting protein 1 (Ndfip1) is required for the exosomal secretion of Nedd4 family proteins. J Biol Chem. 2008;283:32621-7 pubmed publisher
Duriez M, Rossignol J, Sitterlin D. The hepatitis B virus precore protein is retrotransported from endoplasmic reticulum (ER) to cytosol through the ER-associated degradation pathway. J Biol Chem. 2008;283:32352-60 pubmed publisher
Hosoi T, Sasaki M, Miyahara T, Hashimoto C, Matsuo S, Yoshii M, et al. Endoplasmic reticulum stress induces leptin resistance. Mol Pharmacol. 2008;74:1610-9 pubmed publisher
Okamura Y, Saga Y. Pofut1 is required for the proper localization of the Notch receptor during mouse development. Mech Dev. 2008;125:663-73 pubmed publisher
Ito D, Suzuki N. Molecular pathogenesis of seipin/BSCL2-related motor neuron diseases. Ann Neurol. 2007;61:237-50 pubmed
Ulmasov B, Bruno J, Woost P, Edwards J. Tissue and subcellular distribution of CLIC1. BMC Cell Biol. 2007;8:8 pubmed
Kogel D, Schomburg R, Schürmann T, Reimertz C, König H, Poppe M, et al. The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis. J Neurochem. 2003;87:248-56 pubmed
Watson L, Chan A, Berry L, Li J, Sood S, Dickhout J, et al. Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity. J Biol Chem. 2003;278:17438-47 pubmed
Culi J, Mann R. Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila. Cell. 2003;112:343-54 pubmed
Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N. ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature. 2002;419:480-3 pubmed
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Lhuillier L, Dryer S. Developmental regulation of neuronal K(Ca) channels by TGFbeta1: an essential role for PI3 kinase signaling and membrane insertion. J Neurophysiol. 2002;88:954-64 pubmed
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product information

brand :

Novus

master code :

NBP1-97469

SKU :

NBP1-97469-0.1mg

product name :

KDEL Antibody (10C3)

unit size :

0.1 mg (also 0.025 mg)

seo description :

The KDEL Antibody (10C3) - BSA Free from Novus is a mouse monoclonal antibody to KDEL. This antibody reacts with avian,avian - chicken,chicken,human,invertebrate,mammal,mouse,plant,primate,rat,yeast. The KDEL Antibody (10C3) - BSA Free has been validated for the following applications: IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Electron Microscopy.

target :

KDEL

category :

Primary Antibodies

buffer :

PBS (pH 7.2), 50% Glycerol

clonality :

Monoclonal

clone :

10C3

conjugate :

Unconjugated

dilution :

Western Blot 1:1000, Flow Cytometry 1:10 - 1:1000, ELISA, Immunohistochemistry 1:10 - 1:500, Immunocytochemistry/ Immunofluorescence 1:10 - 1:500, Immunoprecipitation, Immunohistochemistry-Paraffin 1:10 - 1:500, Electron Microscopy 1:10 - 1:500

host :

Mouse

immunogen :

Synthetic peptide corresponding to aa 649-654 (S649EKDEL654) of rat Grp78.

isotype :

IgG2a

purity :

Protein G purified

species :

Avian,Avian - Chicken,Chicken,Human,Invertebrate,Mammal,Mouse,Plant,Primate,Rat,Yeast

theoretical molecular weight :

94 kDa

gene symbol :

POGLUT2

applications :

Flow Cytometry,ELISA,Immunohistochemistry,Electron Microscopy,IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence

USD :

359 USD

alt names :

Endoplasmic reticulum resident protein 58, EP58KDEL1, ER protein 58, ERp58, KDEL (Lys-Asp-Glu-Leu) containing 1, KDEL motif-containing 1, KDEL motif-containing protein 1, MGC5302

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage