product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
GLP-1R Antibody - BSA Free
catalog :
NBP1-97308
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
KP1
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, dot blot
more info or order :
citations: 61
Reference
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Mieczkowska A, Bouvard B, Legrand E, Mabilleau G. [Gly²]-GLP-2, But Not Glucagon or [D-Ala²]-GLP-1, Controls Collagen Crosslinking in Murine Osteoblast Cultures. Front Endocrinol (Lausanne). 2021;12:721506 pubmed publisher
Sho H, Fukui K, Yoneda S, Toyoda S, Ozawa H, Ishibashi C, et al. Insulinoma induces a hyperinsulinemia-mediated decrease of GLUT2 and GLP1 receptor in normal pancreatic β-cells. Biochem Biophys Res Commun. 2021;534:702-706 pubmed publisher
Deng H, Yang F, Ma X, Wang Y, Chen Q, Yuan L. Long-Term Liraglutide Administration Induces Pancreas Neogenesis in Adult T2DM Mice. Cell Transplant. 2020;29:963689720927392 pubmed publisher
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Wang M, Li H, Wang Y, Hao Y, Huang Y, Wang X, et al. Anti-Rheumatic Properties of Gentiopicroside Are Associated With Suppression of ROS-NF-κB-NLRP3 Axis in Fibroblast-Like Synoviocytes and NF-κB Pathway in Adjuvant-Induced Arthritis. Front Pharmacol. 2020;11:515 pubmed publisher
Timper K, Del Río Martín A, Cremer A, Bremser S, Alber J, Giavalisco P, et al. GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function. Cell Metab. 2020;31:1189-1205.e13 pubmed publisher
Yang X, Ma X, Don O, Song Y, Chen X, Liu J, et al. Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin. Stem Cell Res Ther. 2020;11:182 pubmed publisher
Chaudhari S, Yazdizadeh Shotorbani P, Tao Y, Davis M, Mallet R, Ma R. Inhibition of interleukin-6 on matrix protein production by glomerular mesangial cells and the pathway involved. Am J Physiol Renal Physiol. 2020;318:F1478-F1488 pubmed publisher
Schoenenberger A, Tempfer H, Lehner C, Egloff J, Mauracher M, Bird A, et al. Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo. Biomaterials. 2020;249:120034 pubmed publisher
Liu Y, Li M, Wei C, Tang L, Sheng Y, Liu Y, et al. TSP1-CD47-SIRPα signaling facilitates the development of endometriosis by mediating the survival of ectopic endometrium. Am J Reprod Immunol. 2020;83:e13236 pubmed publisher
Feng Y, Wang L, Ma X, Yang X, Don O, Chen X, et al. Effect of hCMSCs and liraglutide combination in ALI through cAMP/PKAc/β-catenin signaling pathway. Stem Cell Res Ther. 2020;11:2 pubmed publisher
McCloskey C, Cook D, Kelly B, Azzi F, Allen C, Forsyth A, et al. Metformin Abrogates Age-Associated Ovarian Fibrosis. Clin Cancer Res. 2020;26:632-642 pubmed publisher
Liu X, Chen J, Zhang B, Liu G, Zhao H, Hu Q. KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway. Cell Signal. 2019;64:109415 pubmed publisher
Wu Y, Qin Y, Liu Y, Zhu L, Zhao X, Liu Y, et al. Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation. EBioMedicine. 2019;47:329-340 pubmed publisher
Liu W, Kämpfe Nordström C, Danckwardt Lillieström N, Rask Andersen H. Human Inner Ear Immune Activity: A Super-Resolution Immunohistochemistry Study. Front Neurol. 2019;10:728 pubmed publisher
Ding J, Yin T, Yan N, Cheng Y, Yang J. FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage. Int J Mol Med. 2019;43:2376-2386 pubmed publisher
Cappetta D, Ciuffreda L, Cozzolino A, Esposito G, Scavone C, Sapio L, et al. Dipeptidyl Peptidase 4 Inhibition Ameliorates Chronic Kidney Disease in a Model of Salt-Dependent Hypertension. Oxid Med Cell Longev. 2019;2019:8912768 pubmed publisher
Triulzi T, Forte L, Regondi V, Di Modica M, Ghirelli C, Carcangiu M, et al. HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy. Oncoimmunology. 2019;8:e1512942 pubmed publisher
Zhou D, Chen Y, Zhao Z, Yang R, Xin F, Liu X, et al. Sodium butyrate reduces high-fat diet-induced non-alcoholic steatohepatitis through upregulation of hepatic GLP-1R expression. Exp Mol Med. 2018;50:157 pubmed publisher
Triulzi T, Regondi V, De Cecco L, Cappelletti M, Di Modica M, Paolini B, et al. Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit. Br J Cancer. 2018;119:1487-1494 pubmed publisher
Zhou Y, Li Z, Cao X, Ma H, White P, Xu X, et al. Exendin-4 improves behaviorial deficits via GLP-1/GLP-1R signaling following partial hepatectomy. Brain Res. 2019;1706:116-124 pubmed publisher
van Rooijen J, Qiu S, Timmer Bosscha H, van der Vegt B, Boers J, Schröder C, et al. Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2-positive breast cancer. Eur J Cancer. 2018;103:52-60 pubmed publisher
Rocha Ferreira E, Poupon L, Zelco A, Leverin A, Nair S, Jonsdotter A, et al. Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy. Brain. 2018;141:2925-2942 pubmed publisher
Li D, Wang C, Li Z, Wang H, He J, Zhu J, et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts. Cell Death Dis. 2018;9:840 pubmed publisher
Nomiyama T, Yanase T. GLP-1 receptor agonist as treatment for cancer as well as diabetes: beyond blood glucose control. Expert Rev Endocrinol Metab. 2016;11:357-364 pubmed publisher
Iwaya C, Nomiyama T, Komatsu S, Kawanami T, Tsutsumi Y, Hamaguchi Y, et al. Exendin-4, a Glucagonlike Peptide-1 Receptor Agonist, Attenuates Breast Cancer Growth by Inhibiting NF-?B Activation. Endocrinology. 2017;158:4218-4232 pubmed publisher
Ao J, Zhu X, Chai Z, Cai H, Zhang Y, Zhang K, et al. Colony-Stimulating Factor 1 Receptor Blockade Inhibits Tumor Growth by Altering the Polarization of Tumor-Associated Macrophages in Hepatocellular Carcinoma. Mol Cancer Ther. 2017;16:1544-1554 pubmed publisher
Liu X, Guo X, Li J, Wu M, Zhan X. Interferon-? Aggravated L-Arginine-Induced Acute Pancreatitis in Sprague-Dawley Rats and Its Possible Mechanism: Trypsinogen Activation and Autophagy Up-regulation. Pancreas. 2017;46:619-625 pubmed publisher
Wenjing H, Shuang Y, Weisong L, Haipeng X. Exendin-4 does not modify growth or apoptosis of human colon cancer cells. Endocr Res. 2017;42:209-218 pubmed publisher
He W, Yu S, Wang L, He M, Cao X, Li Y, et al. Exendin-4 inhibits growth and augments apoptosis of ovarian cancer cells. Mol Cell Endocrinol. 2016;436:240-9 pubmed publisher
Steven S, Jurk K, Kopp M, Kröller Schön S, Mikhed Y, Schwierczek K, et al. Glucagon-like peptide-1 receptor signalling reduces microvascular thrombosis, nitro-oxidative stress and platelet activation in endotoxaemic mice. Br J Pharmacol. 2017;174:1620-1632 pubmed publisher
Feng X, Weng D, Zhou F, Owen Y, Qin H, Zhao J, et al. Activation of PPAR? by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization. EBioMedicine. 2016;9:61-76 pubmed publisher
Miao H, Ou J, Peng Y, Zhang X, Chen Y, Hao L, et al. Macrophage ABHD5 promotes colorectal cancer growth by suppressing spermidine production by SRM. Nat Commun. 2016;7:11716 pubmed publisher
Koh M, Gagea M, Sargis T, Lemos R, Grandjean G, Charbono A, et al. A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice. Hepatology. 2016;63:1576-91 pubmed publisher
Tsutsumi Y, Nomiyama T, Kawanami T, Hamaguchi Y, Terawaki Y, Tanaka T, et al. Combined Treatment with Exendin-4 and Metformin Attenuates Prostate Cancer Growth. PLoS ONE. 2015;10:e0139709 pubmed publisher
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product information
brand :
Novus
master code :
NBP1-97308
SKU :
NBP1-97308
product name :
GLP-1R Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
seo description :
The GLP-1R Antibody - BSA Free from Novus is a rabbit polyclonal antibody to GLP-1R. This antibody reacts with canine,human,mouse,rat. The GLP-1R Antibody - BSA Free has been validated for the following applications: Cytometric Bead Assay Standard,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Dot Blot,Simple Western.
target :
GLP-1R
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
dilution :
Western Blot 1:1000, Simple Western 1:100, Immunohistochemistry 1:200, Immunocytochemistry/ Immunofluorescence 1:100, Immunohistochemistry-Paraffin 1:200 - 1:400, Dot Blot reported in scientific literature (PMID 27435156), Knockdown Validated reported in scientific literature (PMID 31900217)
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of the human GLP1R protein (between residues 250-350) [UniProt P43220]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Canine,Human,Mouse,Rat
gene symbol :
GLP1R
Antibody validation :
Biological Validation
accessionNumbers :
P43220
applications :
Immunohistochemistry,Dot Blot,Simple Western,Cytometric Bead Assay Standard,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
GLP-1 receptor, GLP-1R, GLP-1-R, glucagon-like peptide 1 receptor, MGC138331
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.