TDP-43/TARDBP Antibody (3H8) - BSA Free | Novus Biologicals NBP1-92695 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

TDP-43/TARDBP Antibody (3H8) - BSA Free

catalog :

NBP1-92695

quantity :

0.1 ml (also 0.025 ml)

price :

399 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3H8

reactivity :

human, mouse, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse immunohistochemistry; mouse	Verbeeck C, Deng Q, DeJesus Hernandez M, Taylor G, Ceballos Diaz C, Kocerha J, et al. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis. Mol Neurodegener. 2012;7:53 pubmed publisher
	Chevalier E, Audrain M, Ratnam M, Ollier R, Fuchs A, Piorkowska K, et al. Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD. Acta Neuropathol Commun. 2024;12:156 pubmed publisher
	Worrall D, Ayoubi R, Fotouhi M, Southern K, McPherson P, Laflamme C. The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence. F1000Res. 2023;12:277 pubmed publisher
	Evangelista B, Cahalan S, Ragusa J, Mordant A, Necarsulmer J, Perna R, et al. Tandem detergent-extraction and immunoprecipitation of proteinopathy: Scalable enrichment of ALS-associated TDP-43 aggregates. iScience. 2023;26:106645 pubmed publisher
	Kiryu Seo S, Matsushita R, Tashiro Y, Yoshimura T, Iguchi Y, Katsuno M, et al. Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons. EMBO J. 2022;41:e110486 pubmed publisher
	de Rossi P, Lewis A, Furrer J, De Vos L, Demeter T, Zbinden A, et al. FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade. EMBO Rep. 2021;22:e53877 pubmed publisher
	Määttä T, Rettel M, Sridharan S, Helm D, Kurzawa N, Stein F, et al. Aggregation and disaggregation features of the human proteome. Mol Syst Biol. 2020;16:e9500 pubmed publisher
	Frisbie C, Lushnikov A, Krasnoslobodtsev A, Riethoven J, Clarke J, Stepchenkova E, et al. Post-ER Stress Biogenesis of Golgi Is Governed by Giantin. Cells. 2019;8: pubmed publisher
	Casey C, Thomes P, Manca S, Petrosyan A. Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells. Biomolecules. 2018;8: pubmed publisher
	Manca S, Frisbie C, Lagrange C, Casey C, Riethoven J, Petrosyan A. The Role of Alcohol-Induced Golgi Fragmentation for Androgen Receptor Signaling in Prostate Cancer. Mol Cancer Res. 2019;17:225-237 pubmed publisher
	Luchsinger C, Aguilar M, Burgos P, Ehrenfeld P, Mardones G. Functional disruption of the Golgi apparatus protein ARF1 sensitizes MDA-MB-231 breast cancer cells to the antitumor drugs Actinomycin D and Vinblastine through ERK and AKT signaling. PLoS ONE. 2018;13:e0195401 pubmed publisher

product information

master code :

NBP1-92695

SKU :

NBP1-92695

product name :

TDP-43/TARDBP Antibody (3H8) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The TDP-43/TARDBP Antibody (3H8) - BSA Free from Novus is a mouse monoclonal antibody to TDP-43/TARDBP. This antibody reacts with bovine,equine,human,mouse,porcine,rat. The TDP-43/TARDBP Antibody (3H8) - BSA Free has been validated for the following applications: Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,Western Blot,IF/IHC,Immunohistochemistry-Frozen,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry Free-Floating,Knockout Validated.

target :

TDP-43/TARDBP

category :

Primary Antibodies

buffer :

50% PBS, 50% glycerol

clonality :

Monoclonal

clone :

3H8

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Full length recombinant human TDP43 expressed in and purified from E. coli, epitope in peptide HNSNRQLERSGRFGGNPGGF, amino acids 264-283 of the human sequence.

isotype :

IgG1

purity :

Immunogen affinity purified

species :

Bovine,Equine,Human,Mouse,Porcine,Rat

theoretical molecular weight :

43 kDa

gene symbol :

TARDBP

Antibody validation :

Knockout/Knockdown

accessionNumbers :

Q13148

applications :

Western Blot,IF/IHC,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry Free-Floating,Knockout Validated

USD :

399 USD

alt names :

ALS10TAR DNA-binding protein-43, TAR DNA binding protein, TDP43, TDP-43, TDP-43TAR DNA-binding protein 43

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage