product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Lipolysis Stimulated Lipoprotein Receptor Antibody - BSA Free
catalog :
NBP1-89631
quantity :
0.1 ml (also 25 ul)
price :
559 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
20A
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 18
Reference
Arai W, Konno T, Kohno T, Kodera Y, Tsujiwaki M, Shindo Y, et al. Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells. Oncotarget. 2023;14:261-275 pubmed publisher
Ohwada K, Konno T, Kohno T, Nakano M, Ohkuni T, Miyata R, et al. Effects of HMGB1 on Tricellular Tight Junctions via TGF-β Signaling in Human Nasal Epithelial Cells. Int J Mol Sci. 2021;22: pubmed publisher
Kohno T, Konno T, Kikuchi S, Kondoh M, Kojima T. Translocation of LSR from tricellular corners causes macropinocytosis at cell-cell interface as a trigger for breaking out of contact inhibition. FASEB J. 2021;35:e21742 pubmed publisher
Kakiuchi A, Kakuki T, Ohwada K, Kurose M, Kondoh A, Obata K, et al. HDAC inhibitors suppress the proliferation, migration and invasiveness of human head and neck squamous cell carcinoma cells via p63‑mediated tight junction molecules and p21‑mediated growth arrest. Oncol Rep. 2021;45: pubmed publisher
Kodera Y, Kohno T, Konno T, Arai W, Tsujiwaki M, Shindo Y, et al. HMGB1 enhances epithelial permeability via p63/TGF-β signaling in lung and terminal bronchial epithelial cells. Tissue Barriers. 2020;8:1805997 pubmed publisher
Kodera Y, Chiba H, Konno T, Kohno T, Takahashi H, Kojima T. HMGB1-downregulated angulin-1/LSR induces epithelial barrier disruption via claudin-2 and cellular metabolism via AMPK in airway epithelial Calu-3 cells. Biochem Biophys Res Commun. 2020;527:553-560 pubmed publisher
Konno T, Kohno T, Kikuchi S, Shimada H, Satohisa S, Saito T, et al. Epithelial barrier dysfunction and cell migration induction via JNK/cofilin/actin by angubindin-1. Tissue Barriers. 2020;8:1695475 pubmed publisher
Konno T, Kohno T, Kikuchi S, Shimada H, Satohisa S, Takano K, et al. Localization of Tricellular Tight Junction Molecule LSR at Midbody and Centrosome During Cytokinesis in Human Epithelial Cells. J Histochem Cytochem. 2020;68:59-72 pubmed publisher
Konno T, Takano K, Kaneko Y, Kakuki T, Nomura K, Yajima R, et al. Guanylate binding protein-1-mediated epithelial barrier in human salivary gland duct epithelium. Exp Cell Res. 2018;371:31-41 pubmed publisher
Shimada H, Satohisa S, Kohno T, Konno T, Takano K, Takahashi S, et al. Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer. Oncol Lett. 2017;14:6776-6782 pubmed publisher
Takano K, Kakuki T, Kaneko Y, Kohno T, Kikuchi S, Himi T, et al. Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells. PLoS ONE. 2017;12:e0182291 pubmed publisher
Yu D, Holm R, Goscinski M, Trope C, Nesland J, Suo Z. Prognostic and clinicopathological significance of Cacna2d1 expression in epithelial ovarian cancers: a retrospective study. Am J Cancer Res. 2016;6:2088-2097 pubmed
Yang Y, Yang F, Yang F, Li C, Wang Y, Li Z, et al. Gabapentinoid Insensitivity after Repeated Administration is Associated with Down-Regulation of the α(2)δ-1 Subunit in Rats with Central Post-Stroke Pain Hypersensitivity. Neurosci Bull. 2016;32:41-50 pubmed publisher
Miyata R, Kakuki T, Nomura K, Ohkuni T, Ogasawara N, Takano K, et al. Poly(I:C) induced microRNA-146a regulates epithelial barrier and secretion of proinflammatory cytokines in human nasal epithelial cells. Eur J Pharmacol. 2015;761:375-82 pubmed publisher
Sohet F, Lin C, Munji R, Lee S, Ruderisch N, Soung A, et al. LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. J Cell Biol. 2015;208:703-11 pubmed publisher
Horiuchi Hirose M, Kashihara T, Nakada T, Kurebayashi N, Shimojo H, Shibazaki T, et al. Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes. Am J Physiol Heart Circ Physiol. 2011;300:H978-88 pubmed publisher
Tishkoff D, Nibbelink K, Holmberg K, Dandu L, Simpson R. Functional vitamin D receptor (VDR) in the t-tubules of cardiac myocytes: VDR knockout cardiomyocyte contractility. Endocrinology. 2008;149:558-64 pubmed
Rasmussen H, Møller M, Knaus H, Jensen B, Olesen S, Jørgensen N. Subcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heart. Am J Physiol Heart Circ Physiol. 2004;286:H1300-9 pubmed
product information
master code :
NBP1-89631
SKU :
NBP1-89631
product name :
Lipolysis Stimulated Lipoprotein Receptor Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The Lipolysis Stimulated Lipoprotein Receptor Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Lipolysis Stimulated Lipoprotein Receptor. This antibody reacts with human,mouse,porcine,rhesus macaque. The Lipolysis Stimulated Lipoprotein Receptor Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western.
target :
Lipolysis Stimulated Lipoprotein Receptor
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
MSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPR
GWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAES
GSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Porcine,Rhesus Macaque
gene symbol :
LSR
Antibody validation :
Orthogonal Validation
applications :
Western Blot,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western
USD :
559 USD
alt names :
ILDR3, immunoglobulin-like domain containing receptor 3, lipolysis stimulated lipoprotein receptor, lipolysis-stimulated lipoprotein receptor, lipolysis-stimulated receptor, lipolysis-stimulated remnant, LISCH, LISCH protein, LISCH7, liver-specific bHLH-Zip transcription factor, MGC10659, MGC48312, MGC48503
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.