product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TOP2B Antibody - BSA Free
catalog :
NBP1-89527
quantity :
0.1 ml (also 25 ul)
price :
559 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
3G3
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Reference
Wang T, Kyle A, Baker J, Liu N, Ban xe1 th J, Minchinton A. DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost. Sci Rep. 2023;13:12429 pubmed publisher
Lee S, Jun Y, Linares G, Butler B, Yuva Adyemir Y, Moore J, et al. Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD. Neuron. 2023;111:1381-1390.e6 pubmed publisher
Siddaway R, Milos S, Coyaud x, Yun H, Morcos S, Pajovic S, et al. The in vivo Interaction Landscape of Histones H3.1 and H3.3. Mol Cell Proteomics. 2022;21:100411 pubmed publisher
Hu H, Shiflett L, Kobayashi M, Chao M, Wilson A, Mohr I, et al. TOP2β-Dependent Nuclear DNA Damage Shapes Extracellular Growth Factor Responses via Dynamic AKT Phosphorylation to Control Virus Latency. Mol Cell. 2019;74:466-480.e4 pubmed publisher
Ali A, Biswas A, Pal M. HSF1 mediated TNF-α production during proteotoxic stress response pioneers proinflammatory signal in human cells. FASEB J. 2018;:fj201801482R pubmed publisher
Aviner R, Shenoy A, Elroy Stein O, Geiger T. Uncovering Hidden Layers of Cell Cycle Regulation through Integrative Multi-omic Analysis. PLoS Genet. 2015;11:e1005554 pubmed publisher
Gavin M, Torgerson T, Houston E, deRoos P, Ho W, Stray Pedersen A, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A. 2006;103:6659-64 pubmed
product information
master code :
NBP1-89527
SKU :
NBP1-89527
product name :
TOP2B Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The TOP2B Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TOP2B. This antibody reacts with human,insect - drosophila,mouse,rat. The TOP2B Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Simple Western,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.
target :
TOP2B
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
LWKEDLAAFVEELDKVESQEREDVLAGMSGKAIKGKVGK
PKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKK
KGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKG
PKPKREKKEPGTRVRKTPTSSGKPSA
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Insect - Drosophila,Mouse,Rat
gene symbol :
TOP2B
Antibody validation :
Knockout/Knockdown
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
USD :
559 USD
alt names :
antigen MLAA-44, DNA topoisomerase 2-beta, DNA topoisomerase II beta, DNA topoisomerase II, 180 kD, DNA topoisomerase II, beta isozyme, EC 5.99.1.3, top2beta, TOPIIB, topo II beta, topoisomerase (DNA) II beta (180kD), topoisomerase (DNA) II beta 180kDa, topoisomerase II beta, topoisomerase IIb, U937 associated antigen
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.