product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
RBCK1 Antibody - BSA Free
catalog :
NBP1-88301
quantity :
0.1 ml (also 25 ul)
price :
559 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
6C6
reactivity :
human, mouse
application :
western blot, immunoprecipitation, western blot knockout validation
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 2a
Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, et al. HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains. PLoS Pathog. 2017;13:e1006162 pubmed publisher
  • western blot; human; 1:1000; fig s15
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher
Hoshino K, Nakazawa S, Yokobori T, Hagiwara K, Ishii N, Tsukagoshi M, et al. RNF31 promotes proliferation and invasion of hepatocellular carcinoma via nuclear factor kappaB activation. Sci Rep. 2024;14:346 pubmed publisher
Peng R, Wang C, Wang Kan X, Idorn M, Kjaer M, Zhou F, et al. Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1. EMBO Rep. 2022;23:e55839 pubmed publisher
Douglas T, Saleh M. Cross-regulation between LUBAC and caspase-1 modulates cell death and inflammation. J Biol Chem. 2020;295:5216-5228 pubmed publisher
Yamanaka S, Sato Y, Oikawa D, Goto E, Fukai S, Tokunaga F, et al. Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling. Biochem Biophys Res Commun. 2019;: pubmed publisher
Damgaard R, Elliott P, Swatek K, Maher E, Stepensky P, Elpeleg O, et al. OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death. EMBO Mol Med. 2019;11: pubmed publisher
MacDuff D, Baldridge M, Qaqish A, Nice T, Darbandi A, Hartley V, et al. HOIL1 Is Essential for the Induction of Type I and III Interferons by MDA5 and Regulates Persistent Murine Norovirus Infection. J Virol. 2018;92: pubmed publisher
Polajnar M, Dietz M, Heilemann M, Behrends C. Expanding the host cell ubiquitylation machinery targeting cytosolic Salmonella. EMBO Rep. 2017;18:1572-1585 pubmed publisher
Klein T, Fung S, Renner F, Blank M, Dufour A, Kang S, et al. The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nat Commun. 2015;6:8777 pubmed publisher
Lewis M, Vyse S, Shields A, Boeltz S, Gordon P, Spector T, et al. UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases. Am J Hum Genet. 2015;96:221-34 pubmed publisher
product information
master code :
NBP1-88301
SKU :
NBP1-88301
product name :
RBCK1 Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The RBCK1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to RBCK1. This antibody reacts with human,mouse. The RBCK1 Antibody - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunoblotting.
target :
RBCK1
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
SVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVL
QQWVIGQRLARDQETLHSHGVRQNGDSAYLYLLSARNTS
LNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPG
VPQEPGRGQPDAVPEP
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
RBCK1
Antibody validation :
Orthogonal Validation
applications :
Immunoprecipitation,Western Blot,Immunoblotting
USD :
559 USD
alt names :
C20orf18, EC 6.3.2.-, HBV associated factor 4, HBV-associated factor 4, Heme-oxidized IRP2 ubiquitin ligase 1, Hepatitis B virus X-associated protein 4, HOIL-1, RanBP-type and C3HC4-type zinc finger containing 1, ranBP-type and C3HC4-type zinc finger-containing protein 1, RBCC protein interacting with PKC1, RBCK2, RNF54RING finger protein 54, UBCE7IP3HOIL1, ubiquitin conjugating enzyme 7 interacting protein 3, Ubiquitin-conjugating enzyme 7-interacting protein 3, XAP3, XAP4chromosome 20 open reading frame 18, ZRANB4
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.