product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
RAP80 Antibody - BSA Free
catalog :
NBP1-87156
quantity :
0.1 ml (also 25 ul)
price :
559 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; fig 1
Renaud E, Barascu A, Rosselli F. Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells. Nucleic Acids Res. 2016;44:648-56 pubmed publisher
Jiang Q, Foglizzo M, Morozov Y, Yang X, Datta A, Tian L, et al. Autologous K63 deubiquitylation within the BRCA1-A complex licenses DNA damage recognition. J Cell Biol. 2022;221: pubmed publisher
Sherker A, Chaudhary N, Adam S, Heijink A, Noordermeer S, Fradet Turcotte A, et al. Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites. EMBO Rep. 2021;22:e53679 pubmed publisher
Nakamura K, Kustatscher G, Alabert C, Hödl M, Forne I, Völker Albert M, et al. Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination. Mol Cell. 2021;: pubmed publisher
Bodo S, Campagne C, Thin T, Higginson D, Vargas H, Hua G, et al. Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury. J Clin Invest. 2019;129:786-801 pubmed publisher
Yasuhara T, Kato R, Hagiwara Y, Shiotani B, Yamauchi M, Nakada S, et al. Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair. Cell. 2018;175:558-570.e11 pubmed publisher
Watanabe S, Iimori M, Chan D, Hara E, Kitao H, Maehara Y. MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites. Sci Rep. 2018;8:10888 pubmed publisher
Baranes Bachar K, Levy Barda A, Oehler J, Reid D, Soria Bretones I, Voss T, et al. The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair. Mol Cell. 2018;69:866-878.e7 pubmed publisher
Ha K, Ma C, Lin H, Tang L, Lian Z, Zhao F, et al. The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites. Nat Commun. 2017;8:15751 pubmed publisher
product information
master code :
NBP1-87156
SKU :
NBP1-87156
product name :
RAP80 Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The RAP80 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to RAP80. This antibody reacts with human,mouse. The RAP80 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Paraffin,Immunomicroscopy,Immunohistochemistry.
target :
RAP80
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
LLRKAIAESLNSCRPSDASATRSRPLATGPSSQSHQEKT
TDSGLTEGIWQLVPPSLFKGSHISQGNEAEEREEPWDHT
EKTEEEPVSGSSG
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
UIMC1
Antibody validation :
Independent Anitbodies
accessionNumbers :
Q96RL1
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry-Paraffin,Immunomicroscopy,Immunohistochemistry
USD :
559 USD
alt names :
BRCA1-A complex subunit RAP80, RAP80X2HRIP110, receptor associated protein 80, Receptor-associated protein 80, retinoid x receptor interacting protein, Retinoid X receptor-interacting protein 110, RXRIP110, ubiquitin interaction motif containing 1, Ubiquitin interaction motif-containing protein 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.