product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
XRCC1 Antibody - BSA Free
catalog :
NBP1-87154
quantity :
0.1 ml (also 25 ul)
price :
549 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Reference
Gautam A, Fawcett H, Burdova K, Brazina J, Caldecott K. APE1-dependent base excision repair of DNA photodimers in human cells. Mol Cell. 2023;83:3669-3678.e7 pubmed publisher
Bilkis R, Lake R, Cooper K, Tomkinson A, Fan H. The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions. Nucleic Acids Res. 2023;51:7342-7356 pubmed publisher
Demin A, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, et al. XRCC1 prevents toxic PARP1 trapping during DNA base excision repair. Mol Cell. 2021;81:3018-3030.e5 pubmed publisher
Komulainen E, Badman J, Rey S, Rulten S, Ju L, Fennell K, et al. Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures. EMBO Rep. 2021;22:e51851 pubmed publisher
Wu W, Hill S, Nathan W, Paiano J, Callen E, Wang D, et al. Neuronal enhancers are hotspots for DNA single-strand break repair. Nature. 2021;593:440-444 pubmed publisher
Hong D, Liu T, Huang W, Liao Y, Wang L, Zhang Z, et al. Gremlin1 Delivered by Mesenchymal Stromal Cells Promoted Epithelial-Mesenchymal Transition in Human Esophageal Squamous Cell Carcinoma. Cell Physiol Biochem. 2018;47:1785-1799 pubmed publisher
product information
master code :
NBP1-87154
SKU :
NBP1-87154
product name :
XRCC1 Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The XRCC1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to XRCC1. This antibody reacts with human. The XRCC1 Antibody - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockdown Validated.
target :
XRCC1
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
WDRVKIVCSQPYSKDSPFGLSFVRFHSPPDKDEAEAPSQ
KVTVTKLGQFRVKEEDESANSLRPGALFFSRINKTSPVT
ASDPAGPSYAAATLQASSAASSASPVSRAIGSTSKPQES
PKGKRKLDLNQEEKKT
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human
gene symbol :
XRCC1
Antibody validation :
Knockout/Knockdown
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockdown Validated
USD :
549 USD
alt names :
DNA repair protein XRCC1, RCC, X-ray repair complementing defective repair in Chinese hamster cells 1, X-ray repair cross-complementing protein 1, X-ray-repair, complementing defective, repair in Chinese hamster
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.