product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
cGAS Antibody - BSA Free
catalog :
NBP1-86761
quantity :
0.1 ml (also 25 ul)
price :
579 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 11
Reference
Li K, Gong Y, Qiu D, Tang H, Zhang J, Yuan Z, et al. Hyperbaric oxygen facilitates teniposide-induced cGAS-STING activation to enhance the antitumor efficacy of PD-1 antibody in HCC. J Immunother Cancer. 2022;10: pubmed publisher
Lohinai Z, DORA D, Caldwell C, Rivard C, Suda K, Yu H, et al. Loss of STING expression is prognostic in non-small cell lung cancer. J Surg Oncol. 2022;125:1042-1052 pubmed publisher
Deater M, Tamhankar M, Lloyd R. TDRD3 is an antiviral restriction factor that promotes IFN signaling with G3BP1. PLoS Pathog. 2022;18:e1010249 pubmed publisher
Berndt N, Wolf C, Fischer K, Cura Costa E, Knuschke P, Zimmermann N, et al. Photosensitivity and cGAS-Dependent IFN-1 Activation in Patients with Lupus and TREX1 Deficiency. J Invest Dermatol. 2022;142:633-640.e6 pubmed publisher
Luzwick J, Dombi E, Boisvert R, Roy S, Park S, Kunnimalaiyaan S, et al. MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling pathway. Sci Adv. 2021;7:eabf9441 pubmed publisher
Schwertner B, Lindner G, Toledo Stauner C, Klapproth E, Magnus C, Rohrhofer A, et al. Nectin-1 Expression Correlates with the Susceptibility of Malignant Melanoma to Oncolytic Herpes Simplex Virus In Vitro and In Vivo. Cancers (Basel). 2021;13: pubmed publisher
Chen H, Zhang J, Wang Y, Simoneau A, Yang H, Levine A, et al. cGAS suppresses genomic instability as a decelerator of replication forks. Sci Adv. 2020;6: pubmed publisher
Verrier E, Yim S, Heydmann L, El Saghire H, Bach C, Turon Lagot V, et al. Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes. Hepatology. 2018;68:1695-1709 pubmed publisher
Schuelke J, Meyers N, Reitmaier S, Klose S, Ignatius A, Claes L. Intramembranous bone formation after callus distraction is augmented by increasing axial compressive strain. PLoS ONE. 2018;13:e0195466 pubmed publisher
Jeon J, Kang L, Lee K, Cho C, Song E, Kim W, et al. 3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis. J Cell Mol Med. 2018;22:57-66 pubmed publisher
Antunes J, Tsaryk R, Gonçalves R, Pereira C, Landes C, Brochhausen C, et al. Poly(γ-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells. Tissue Eng Part A. 2015;21:1869-85 pubmed publisher
product information
master code :
NBP1-86761
SKU :
NBP1-86761
product name :
cGAS Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The cGAS Antibody - BSA Free from Novus is a rabbit polyclonal antibody to cGAS. This antibody reacts with human. The cGAS Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Simple Western.
target :
cGAS
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
RKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEIL
NNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERF
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human
gene symbol :
CGAS
Antibody validation :
Orthogonal Validation
applications :
Immunohistochemistry-Paraffin,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,IF/IHC,Western Blot,Simple Western
USD :
579 USD
alt names :
C6orf150, c-GAS, cyclic GMP-AMP synthase, h-cGAS, Mab-21 domain containing 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.