PICALM Antibody - BSA Free | Novus Biologicals NBP1-86658 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

PICALM Antibody - BSA Free

catalog :

NBP1-86658

quantity :

0.1 ml (also 25 ul)

price :

559 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

3H8

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; fig 2 western blot; human; fig 1	Thomas R, Henson A, Gerrish A, Jones L, Williams J, Kidd E. Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's disease. BMC Neurosci. 2016;17:50 pubmed publisher
	Zhang Z, Yu K, You Y, Jiang P, Wu Z, DeTure M, et al. Comprehensive characterization of human brain-derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications. J Extracell Vesicles. 2023;12:e12358 pubmed publisher
	Azarnia Tehran D, Kochlamazashvili G, Pampaloni N, Sposini S, Shergill J, Lehmann M, et al. Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity. Sci Adv. 2022;8:eabl5032 pubmed publisher
	Tsai Teng T, Chin Chu C, Li Ya L, Wan Ping C, Chung Kuang L, Chien Chang S, et al. Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice. J Biomed Sci. 2016;23:49 pubmed publisher
	Mercer J, Argus J, Crabtree D, KEENAN M, Wilks M, Chi J, et al. Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis. PLoS ONE. 2015;10:e0129776 pubmed publisher
	Zhao Z, Sagare A, Ma Q, Halliday M, Kong P, Kisler K, et al. Central role for PICALM in amyloid-Î² blood-brain barrier transcytosis and clearance. Nat Neurosci. 2015;18:978-87 pubmed publisher
	Verbeeck C, Deng Q, DeJesus Hernandez M, Taylor G, Ceballos Diaz C, Kocerha J, et al. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis. Mol Neurodegener. 2012;7:53 pubmed publisher

product information

master code :

NBP1-86658

SKU :

NBP1-86658

product name :

PICALM Antibody - BSA Free

unit size :

0.1 ml (also 25 ul)

description :

The PICALM Antibody - BSA Free from Novus is a rabbit polyclonal antibody to PICALM. This antibody reacts with human,mouse,rat. The PICALM Antibody - BSA Free has been validated for the following applications: Western Blot,IF/IHC,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

PICALM

category :

Primary Antibodies

buffer :

PBS (pH 7.2) and 40% Glycerol

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Rabbit

immunogen :

DIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATT
LSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKE
QRL
This antibody was developed against Recombinant Protein corresponding to amino acids:

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Rat

gene symbol :

PICALM

Antibody validation :

Independent Anitbodies

applications :

Western Blot,IF/IHC,Immunohistochemistry,Immunohistochemistry-Paraffin

USD :

559 USD

alt names :

CALMclathrin assembly lymphoid-myeloid leukemia, Clathrin assembly lymphoid myeloid leukemia protein, CLTHphosphatidylinositol-binding clathrin assembly protein, LAP, phosphatidylinositol binding clathrin assembly protein

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage