product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
P4HA1 Antibody - BSA Free
catalog :
NBP1-84398
quantity :
0.1 ml (also 25 ul)
price :
559 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
LL002
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:1000; loading ...; fig s1h
  • western blot; human; loading ...; fig 1a
Eriksson J, Le Joncour V, Jahkola T, Juteau S, Laakkonen P, Saksela O, et al. Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas, and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls. Mol Oncol. 2020;14:742-762 pubmed publisher
Liu Y, Gu Y, Ng S, Deng Z, Lyon C, Koay E, et al. Circulating levels of hydroxylated bradykinin function as an indicator of tissue HIF-1α expression. Sci Bull (Beijing). 2020;65:1570-1579 pubmed publisher
Bhute V, Harte J, Houghton J, Maxwell P. Mannose Binding Lectin Is Hydroxylated by Collagen Prolyl-4-hydroxylase and Inhibited by Some PHD Inhibitors. Kidney360. 2020;1:447-457 pubmed publisher
Kaluz S, Zhang Q, Kuranaga Y, Yang H, Osuka S, Bhattacharya D, et al. Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth. Oncogene. 2021;40:5182-5191 pubmed publisher
Morimoto C, Takedachi M, Kawasaki K, Shimomura J, Murata M, Hirai A, et al. Hypoxia stimulates collagen hydroxylation in gingival fibroblasts and periodontal ligament cells. J Periodontol. 2021;: pubmed publisher
Wiraja C, Zhu Y, Lio D, Yeo D, Xie M, Fang W, et al. Framework nucleic acids as programmable carrier for transdermal drug delivery. Nat Commun. 2019;10:1147 pubmed publisher
product information
master code :
NBP1-84398
SKU :
NBP1-84398
product name :
P4HA1 Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The P4HA1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to P4HA1. This antibody reacts with human,mouse,rat. The P4HA1 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,EA,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence.
target :
P4HA1
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
DYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQ
QGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEK
DVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRG
EGIKMTPRRQKKLFCRYHDGNRNPK
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
gene symbol :
P4HA1
Antibody validation :
Orthogonal Validation
applications :
EA,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence
USD :
559 USD
alt names :
2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), 2-oxoglutarate-4-dioxygenase subunit alpha-1, 4-PH alpha-1, alpha polypeptide I, EC 1.14.11.2, Procollagen-proline, prolyl 4-hydroxylase, alpha polypeptide I
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.