product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
ALKBH5 Antibody - BSA Free
catalog :
NBP1-82188
quantity :
0.1 ml (also 25 ul)
price :
549 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 8
Reference
Cie x15b la M, Ngoc P, Muthukumar S, Todisco G, Madej M, Fritz H, et al. m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis. Mol Cell. 2023;83:1165-1179.e11 pubmed publisher
Hesser C, Walsh D. YTHDF2 Is Downregulated in Response to Host Shutoff Induced by DNA Virus Infection and Regulates Interferon-Stimulated Gene Expression. J Virol. 2023;97:e0175822 pubmed publisher
Su X, Shen Y, Jin Y, Kim I, Weintraub N, Tang Y. Aging-Associated Differences in Epitranscriptomic m6A Regulation in Response to Acute Cardiac Ischemia/Reperfusion Injury in Female Mice. Front Pharmacol. 2021;12:654316 pubmed publisher
Querido E, Sfeir A, Chartrand P. Imaging of Telomerase RNA by Single-Molecule Inexpensive FISH Combined with Immunofluorescence. STAR Protoc. 2020;1:100104 pubmed publisher
Jiang Y, Wan Y, Gong M, Zhou S, Qiu J, Cheng W. RNA demethylase ALKBH5 promotes ovarian carcinogenesis in a simulated tumour microenvironment through stimulating NF-κB pathway. J Cell Mol Med. 2020;24:6137-6148 pubmed publisher
Li X, Jin F, Wang B, Yin X, Hong W, Tian F. The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of CYR61 mRNA. Theranostics. 2019;9:3853-3865 pubmed publisher
Zhang C, Zhi W, Lu H, Samanta D, Chen I, Gabrielson E, et al. Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells. Oncotarget. 2016;7:64527-64542 pubmed publisher
Zhang C, Samanta D, Lu H, Bullen J, Zhang H, Chen I, et al. Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m?A-demethylation of NANOG mRNA. Proc Natl Acad Sci U S A. 2016;113:E2047-56 pubmed publisher
product information
master code :
NBP1-82188
SKU :
NBP1-82188
product name :
ALKBH5 Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The ALKBH5 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to ALKBH5. This antibody reacts with human,mouse. The ALKBH5 Antibody - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Knockdown Validated.
target :
ALKBH5
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
EKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEP
YPVSGAKRKYQEDSDPERSDYEEQQLQKEEEARKVKSGI
RQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVD
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
theoretical molecular weight :
51 kDa
gene symbol :
ALKBH5
Antibody validation :
Knockout/Knockdown
accessionNumbers :
Q6P6C2
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Knockdown Validated
USD :
549 USD
alt names :
ABH5OFOXD, alkB, alkylation repair homolog 5 (E. coli), Alkylated DNA repair protein alkB homolog 5, EC 1.14.11.-, FLJ20308, OFOXD1, oxoglutarate and iron-dependent oxygenase domain containing, probable alpha-ketoglutarate-dependent dioxygenase ABH5
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.