product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
NPLOC4 Antibody - BSA Free
catalog :
NBP1-82166
quantity :
0.1 ml (also 25 ul)
price :
559 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Reference
Kanellis D, Zisi A, Skrott Z, Lemmens B, Espinoza J, Kosar M, et al. Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET. Cell Death Differ. 2023;30:1666-1678 pubmed publisher
Chroma K, Skrott Z, Gursky J, Bacovsky J, Moudry P, Buchtova T, et al. A drug repurposing strategy for overcoming human multiple myeloma resistance to standard-of-care treatment. Cell Death Dis. 2022;13:203 pubmed publisher
Buchtova T, Skrott Z, Chroma K, Rehulka J, Dzubak P, Hajduch M, et al. Cannabidiol-induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET. Mol Oncol. 2022;16:1541-1554 pubmed publisher
Serra R, Zhao T, Huq S, Gorelick N, Casaos J, Cecia A, et al. Disulfiram and copper combination therapy targets NPL4, cancer stem cells and extends survival in a medulloblastoma model. PLoS ONE. 2021;16:e0251957 pubmed publisher
Franz A, Valledor P, Ubieto Capella P, Pilger D, Galarreta A, Lafarga V, et al. USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork. Cell Rep. 2021;37:109819 pubmed publisher
Neglia L, Oggioni M, Mercurio D, De Simoni M, Fumagalli S. Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury. Cell Mol Immunol. 2019;: pubmed publisher
Skrott Z, Mistrik M, Andersen K, Friis S, Majera D, Gursky J, et al. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017;552:194-199 pubmed publisher
product information
master code :
NBP1-82166
SKU :
NBP1-82166
product name :
NPLOC4 Antibody - BSA Free
unit size :
0.1 ml (also 25 ul)
description :
The NPLOC4 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to NPLOC4. This antibody reacts with human,mouse,rat. The NPLOC4 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry.
target :
NPLOC4
category :
Primary Antibodies
buffer :
PBS (pH 7.2) and 40% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
VRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDVDKFG
NEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFP
IENRDVLGETQDFHSLATYLSQNTSSVFLDTISDFHLLL
FLVTNE
This antibody was developed against Recombinant Protein corresponding to amino acids:
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
gene symbol :
NPLOC4
Antibody validation :
Independent Anitbodies
applications :
Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry
USD :
559 USD
alt names :
FLJ20657, FLJ23742, KIAA1499nuclear protein localization protein 4 homolog, NPL4Protein NPL4, nuclear protein localization 4 homolog (S. cerevisiae)
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.