Desmoglein-3 Antibody (5H10) - BSA Free | Novus Biologicals NBP1-78984 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Desmoglein-3 Antibody (5H10) - BSA Free

catalog :

NBP1-78984

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5H10

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, dot blot

more info or order :

Novus Biologicals product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human western blot; human	Tsang S, Liu L, Teh M, Wheeler A, Grose R, Hart I, et al. Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src. PLoS ONE. 2010;5:e14211 pubmed publisher
immunoprecipitation; human western blot; human	Mahoney M, Hu Y, Brennan D, Bazzi H, Christiano A, Wahl J. Delineation of diversified desmoglein distribution in stratified squamous epithelia: implications in diseases. Exp Dermatol. 2006;15:101-9 pubmed
immunoprecipitation; human immunocytochemistry; human western blot; human	Weiske J, Schoneberg T, Schroder W, Hatzfeld M, Tauber R, Huber O. The fate of desmosomal proteins in apoptotic cells. J Biol Chem. 2001;276:41175-81 pubmed
western blot; human	Proby C, Ota T, Suzuki H, Koyasu S, Gamou S, Shimizu N, et al. Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris. Br J Dermatol. 2000;142:321-30 pubmed
	Assaf S, Vodo D, Malovitski K, Mohamad J, Bergson S, Feller Y, et al. Up-regulation of ST18 in pemphigus vulgaris drives a self-amplifying p53-dependent pathomechanism resulting in decreased desmoglein 3 expression. Sci Rep. 2022;12:5958 pubmed publisher
	Davis L, Musso J, Soman D, Louey S, Nelson J, Jonker S. Role of adenosine signaling in coordinating cardiomyocyte function and coronary vascular growth in chronic fetal anemia. Am J Physiol Regul Integr Comp Physiol. 2018;315:R500-R508 pubmed publisher
	Chimote A, Balajthy A, Arnold M, Newton H, Hajdu P, Qualtieri J, et al. A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment. Sci Signal. 2018;11: pubmed publisher
	Hirata Y, Furuhashi K, Ishii H, Li H, Pinho S, Ding L, et al. CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine. Cell Stem Cell. 2018;22:445-453.e5 pubmed publisher
	Walter E, Vielmuth F, Rotkopf L, Sárdy M, Horváth O, Goebeler M, et al. Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus. Sci Rep. 2017;7:3579 pubmed publisher
	Mediavilla Varela M, Castro J, Chiappori A, Noyes D, Hernandez D, Allard B, et al. A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment. Neoplasia. 2017;19:530-536 pubmed publisher
	Clancy Thompson E, Perekslis T, Croteau W, Alexander M, Chabanet T, Turk M, et al. Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease. Cancer Immunol Res. 2015;3:956-67 pubmed publisher
	Del Ry S, Moscato S, Bianchi F, Morales M, Dolfi A, Burchielli S, et al. Altered expression of connexin 43 and related molecular partners in a pig model of left ventricular dysfunction with and without dipyrydamole therapy. Pharmacol Res. 2015;95-96:92-101 pubmed publisher
	Ribeiro A, Fernandes V, Orensanz L, Martínez M, Recio P, Martínez Saénz A, et al. Mechanisms involved in the adenosine-induced vasorelaxation to the pig prostatic small arteries. Purinergic Signal. 2011;7:413-25 pubmed publisher
	Haschemi A, Wagner O, Marculescu R, Wegiel B, Robson S, Gagliani N, et al. Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages. J Immunol. 2007;178:5921-9 pubmed
	Lucchese A, Mittelman A, Lin M, Kanduc D, Sinha A. Epitope definition by proteomic similarity analysis: identification of the linear determinant of the anti-Dsg3 MAb 5H10. J Transl Med. 2004;2:43 pubmed
	Nguyen D, Montesinos M, Williams A, Kelly M, Cronstein B. Th1 cytokines regulate adenosine receptors and their downstream signaling elements in human microvascular endothelial cells. J Immunol. 2003;171:3991-8 pubmed
	Wahl J. Generation of monoclonal antibodies specific for desmoglein family members. Hybrid Hybridomics. 2002;21:37-44 pubmed
	Khoa N, Montesinos M, Reiss A, Delano D, Awadallah N, Cronstein B. Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells. J Immunol. 2001;167:4026-32 pubmed

product information

master code :

NBP1-78984

SKU :

NBP1-78984

product name :

Desmoglein-3 Antibody (5H10) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The Desmoglein-3 Antibody (5H10) - BSA Free from Novus is a mouse monoclonal antibody to Desmoglein-3. This antibody reacts with human,mouse. The Desmoglein-3 Antibody (5H10) - BSA Free has been validated for the following applications: Cytometric Bead Assay Standard,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Dot Blot.

target :

Desmoglein-3

category :

Primary Antibodies

buffer :

Tris-Glycine and 0.15M NaCl

clonality :

Monoclonal

clone :

5H10

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

The extracellular domain of human Desmoglein 3 [Swiss-Prot# P32926]

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse

theoretical molecular weight :

130 kDa

gene symbol :

DSG3

accessionNumbers :

P32926

applications :

Cytometric Bead Assay Standard,Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Dot Blot

USD :

409 USD

alt names :

Cadherin family member 6, CDHF6130-kD pemphigus vulgaris antigen, desmoglein 3, desmoglein 3 (pemphigus vulgaris antigen), desmoglein-3, DKFZp686P23184,130 kDa pemphigus vulgaris antigen, pemphigus vulgaris antigen, PVA

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage