product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PIEZO2 Antibody - BSA Free
catalog :
NBP1-78624
quantity :
0.1 ml (also 0.025 ml)
price :
419 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:200; fig 3
  • immunoprecipitation; mouse; fig 2
Narayanan P, Sondermann J, Rouwette T, Karaca S, Urlaub H, Mitkovski M, et al. Native Piezo2 Interactomics Identifies Pericentrin as a Novel Regulator of Piezo2 in Somatosensory Neurons. J Proteome Res. 2016;15:2676-87 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 3
Florez Paz D, Bali K, Kuner R, Gomis A. A critical role for Piezo2 channels in the mechanotransduction of mouse proprioceptive neurons. Sci Rep. 2016;6:25923 pubmed publisher
Tiwari N, Smith C, Sharma D, Shen S, Mehta P, Qiao L. Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons. Cell Rep. 2024;43:114230 pubmed publisher
Wan X, Zhou Q, Chen H, Li Z, Mo M, Liu Z, et al. Astragaloside IV improves slow transit constipation by regulating gut microbiota and enterochromaffin cells. Front Pharmacol. 2023;14:1196210 pubmed publisher
Zhu Z, Chen X, Chen S, Hu C, Guo R, Wu Y, et al. Examination of the mechanism of Piezo ion channel in 5-HT synthesis in the enterochromaffin cell and its association with gut motility. Front Endocrinol (Lausanne). 2023;14:1193556 pubmed publisher
Chen G, Gao X, Chen J, Peng L, Chen S, Tang C, et al. Actomyosin Activity and Piezo1 Activity Synergistically Drive Urinary System Fibroblast Activation. Adv Sci (Weinh). 2023;10:e2303369 pubmed publisher
Duan M, Jia Y, Huo L, Gao Y, Wang J, Zhang W, et al. Potentiation of PIEZO2 mechanically-activated currents in sensory neurons mediates vincristine-induced mechanical hypersensitivity. Acta Pharm Sin B. 2023;13:3365-3381 pubmed publisher
Scavuzzo M, Letai K, Maeno Hikichi Y, Wulftange W, Shah I, Rameshbabu J, et al. Enteric glial hub cells coordinate intestinal motility. bioRxiv. 2023;: pubmed publisher
Liu L, Zhao Y, An W, Zhao M, Ding N, Liu H, et al. Piezo2 Channel Upregulation is Involved in Mechanical Allodynia in CYP-Induced Cystitis Rats. Mol Neurobiol. 2023;60:5000-5012 pubmed publisher
Madar J, Tiwari N, Smith C, Sharma D, Shen S, Elmahdi A, et al. Piezo2 regulates colonic mechanical sensitivity in a sex specific manner in mice. Nat Commun. 2023;14:2158 pubmed publisher
Gon xe7 alves A, Moura R, Correia Pinto J, Nogueira Silva C. Intraluminal chloride regulates lung branching morphogenesis: involvement of PIEZO1/PIEZO2. Respir Res. 2023;24:42 pubmed publisher
Foote A, Tibbetts J, Bartley S, Thibeault S. Localization of TRPV3/4 and PIEZO1/2 sensory receptors in murine and human larynges. Laryngoscope Investig Otolaryngol. 2022;7:1963-1972 pubmed publisher
Michalak Mićka K, R xfc tsche D, Mazzone L, B xfc chler V, Moehrlen U, Klar A, et al. Human fetal skin derived merkel cells display distinctive characteristics in vitro and in bio-engineered skin substitutes in vivo. Front Bioeng Biotechnol. 2022;10:983870 pubmed publisher
Han H, Jeong S, Cho Y, Choi S, Bae Y. Expression of Piezo2 in the Dental Pulp, Sensory Root, and Trigeminal Ganglion and Its Coexpression with Vesicular Glutamate Transporters. J Endod. 2022;48:1407-1413 pubmed publisher
Jones L, Jin B, Martin A, Wei L, Ro S, Keating D. Diminished Piezo2-Dependent Tactile Sensitivity Occurs in Aging Human Gut and Slows Gastrointestinal Transit in Mice. Gastroenterology. 2022;162:1755-1757.e2 pubmed publisher
Du G, Chen W, Li L, Zhang Q. The potential role of mechanosensitive ion channels in substrate stiffness-regulated Ca2+ response in chondrocytes. Connect Tissue Res. 2021;:1-10 pubmed publisher
Nencini S, Morgan M, Thai J, Jobling A, Mazzone S, Ivanusic J. Piezo2 Knockdown Inhibits Noxious Mechanical Stimulation and NGF-Induced Sensitization in A-Delta Bone Afferent Neurons. Front Physiol. 2021;12:644929 pubmed publisher
Fang J, Hou F, Wu S, Liu Y, Wang L, Zhang J, et al. Piezo2 downregulation via the Cre-lox system affects aqueous humor dynamics in mice. Mol Vis. 2021;27:354-364 pubmed
Dhar A, Kuramoto E, Fukushima M, Iwai H, Yamanaka A, Goto T. The Periodontium Damage Induces Neuronal Cell Death in the Trigeminal Mesencephalic Nucleus and Neurodegeneration in the Trigeminal Motor Nucleus in C57BL/6J Mice. Acta Histochem Cytochem. 2021;54:11-19 pubmed publisher
Goto T, Kuramoto E, Dhar A, Wang R, Seki H, Iwai H, et al. Neurodegeneration of Trigeminal Mesencephalic Neurons by the Tooth Loss Triggers the Progression of Alzheimer's Disease in 3×Tg-AD Model Mice. J Alzheimers Dis. 2020;76:1443-1459 pubmed publisher
Lu H, Nguyen T, Hong G, Pak S, Kim H, Kim H, et al. Tentonin 3/TMEM150C senses blood pressure changes in the aortic arch. J Clin Invest. 2020;130:3671-3683 pubmed publisher
Morozumi W, Inagaki S, Iwata Y, Nakamura S, Hara H, Shimazawa M. Piezo channel plays a part in retinal ganglion cell damage. Exp Eye Res. 2020;191:107900 pubmed publisher
Du G, Li L, Zhang X, Liu J, Hao J, Zhu J, et al. Roles of TRPV4 and piezo channels in stretch-evoked Ca2+ response in chondrocytes. Exp Biol Med (Maywood). 2020;245:180-189 pubmed publisher
Mazzuoli Weber G, Kugler E, Bühler C, Kreutz F, Demir I, Ceyhan O, et al. Piezo proteins: incidence and abundance in the enteric nervous system. Is there a link with mechanosensitivity?. Cell Tissue Res. 2019;375:605-618 pubmed publisher
Narayanan P, Hütte M, Kudryasheva G, Taberner F, Lechner S, Rehfeldt F, et al. Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons. elife. 2018;7: pubmed publisher
Nencini S, Ivanusic J. Mechanically sensitive A? nociceptors that innervate bone marrow respond to changes in intra-osseous pressure. J Physiol. 2017;595:4399-4415 pubmed publisher
Alcaino C, Knutson K, Gottlieb P, Farrugia G, Beyder A. Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4. Channels (Austin). 2017;11:245-253 pubmed publisher
Righi S, Pileri S, Agostinelli C, Bacci F, Spagnolo S, Sabattini E. Reproducibility of SOX-11 detection in decalcified bone marrow tissue in mantle cell lymphoma patients. Hum Pathol. 2017;59:94-101 pubmed publisher
Ribera Cortada I, Martinez D, Amador V, Royo C, Navarro A, Beà S, et al. Plasma cell and terminal B-cell differentiation in mantle cell lymphoma mainly occur in the SOX11-negative subtype. Mod Pathol. 2015;28:1435-47 pubmed publisher
Davidson B, Holth A, Hellesylt E, Tan T, Huang R, Tropé C, et al. The clinical role of epithelial-mesenchymal transition and stem cell markers in advanced-stage ovarian serous carcinoma effusions. Hum Pathol. 2015;46:1-8 pubmed publisher
Kuo P, Leshchenko V, Fazzari M, Perumal D, Gellen T, He T, et al. High-resolution chromatin immunoprecipitation (ChIP) sequencing reveals novel binding targets and prognostic role for SOX11 in mantle cell lymphoma. Oncogene. 2015;34:1231-40 pubmed publisher
product information
master code :
NBP1-78624
SKU :
NBP1-78624
product name :
PIEZO2 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The PIEZO2 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to PIEZO2. This antibody reacts with guinea pig,human,mouse,rat. The PIEZO2 Antibody - BSA Free has been validated for the following applications: Immunohistochemistry,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating.
target :
PIEZO2
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of the human PIEZO2 protein (between residues 1600-1650) [UniProt# Q9H5I5]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Guinea Pig,Human,Mouse,Rat
gene symbol :
PIEZO2
accessionNumbers :
Q9H5I5
applications :
Immunohistochemistry,Western Blot,Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating
USD :
419 USD
alt names :
C18orf30, C18orf58, FAM38B, FAM38B2, family with sequence similarity 38, member B, family with sequence similarity 38, member B2, FLJ23144, FLJ23403, FLJ25916, FLJ34907, FLJ37734, FLJ45725, HsT748, HsT771, piezo-type mechanosensitive ion channel component 2, protein PIEZO2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.