product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PIEZO1 Antibody - BSA Free
catalog :
NBP1-78537
quantity :
0.1 ml (also 0.025 ml)
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
MECA-79R
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 44
Reference
Walker M, Pringle E, Ciccone G, Oliver Cervell xf3 L, Tassieri M, Gourdon D, et al. Mind the Viscous Modulus: The Mechanotransductive Response to the Viscous Nature of Isoelastic Matrices Regulates Stem Cell Chondrogenesis. Adv Healthc Mater. 2024;13:e2302571 pubmed publisher
Raha A, Wu Y, Zhong L, Raveenthiran J, Hong M, Taiyab A, et al. Exploring Piezo1, Piezo2, and TMEM150C in human brain tissues and their correlation with brain biomechanical characteristics. Mol Brain. 2023;16:83 pubmed publisher
Zhu Z, Chen X, Chen S, Hu C, Guo R, Wu Y, et al. Examination of the mechanism of Piezo ion channel in 5-HT synthesis in the enterochromaffin cell and its association with gut motility. Front Endocrinol (Lausanne). 2023;14:1193556 pubmed publisher
Wen D, Gao Y, Liu Y, Ho C, Sun J, Huang L, et al. Matrix stiffness-induced α-tubulin acetylation is required for skin fibrosis formation through activation of Yes-associated protein. MedComm (2020). 2023;4:e319 pubmed publisher
Madar J, Tiwari N, Smith C, Sharma D, Shen S, Elmahdi A, et al. Piezo2 regulates colonic mechanical sensitivity in a sex specific manner in mice. Nat Commun. 2023;14:2158 pubmed publisher
Zhang F, He X, Dong K, Yang L, Ma B, Liu Y, et al. Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation. J Nanobiotechnology. 2023;21:91 pubmed publisher
Dela Justina V, de Freitas R, Arishe O, Giachini F, Webb R, Priviero F. Piezo1 activation induces relaxation of the pudendal artery and corpus cavernosum. Front Physiol. 2023;14:998951 pubmed publisher
Wang Y, Groeger S, Yong J, Ruf S. Orthodontic Compression Enhances Macrophage M2 Polarization via Histone H3 Hyperacetylation. Int J Mol Sci. 2023;24: pubmed publisher
Gon xe7 alves A, Moura R, Correia Pinto J, Nogueira Silva C. Intraluminal chloride regulates lung branching morphogenesis: involvement of PIEZO1/PIEZO2. Respir Res. 2023;24:42 pubmed publisher
Shi S, Kang X, Zhou Z, He Z, Zheng S, He S. Excessive mechanical stress-induced intervertebral disc degeneration is related to Piezo1 overexpression triggering the imbalance of autophagy/apoptosis in human nucleus pulpous. Arthritis Res Ther. 2022;24:119 pubmed publisher
Allen A, Maddala R, Eldawy C, Rao P. Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses. Int J Mol Sci. 2022;23: pubmed publisher
Chubinskiy Nadezhdin V, Semenova S, Vasileva V, Shatrova A, Pugovkina N, Negulyaev Y. Store-Operated Ca2+ Entry Contributes to Piezo1-Induced Ca2+ Increase in Human Endometrial Stem Cells. Int J Mol Sci. 2022;23: pubmed publisher
Wee J, Pak S, Kim T, Hong G, Lee J, Nan J, et al. Tentonin 3/TMEM150C regulates glucose-stimulated insulin secretion in pancreatic β-cells. Cell Rep. 2021;37:110067 pubmed publisher
Matsunaga M, Kimura M, Ouchi T, Nakamura T, Ohyama S, Ando M, et al. Mechanical Stimulation-Induced Calcium Signaling by Piezo1 Channel Activation in Human Odontoblast Reduces Dentin Mineralization. Front Physiol. 2021;12:704518 pubmed publisher
Vasileva V, Morachevskaya E, Sudarikova A, Negulyaev Y, Chubinskiy Nadezhdin V. Selective Chemical Activation of Piezo1 in Leukemia Cell Membrane: Single Channel Analysis. Int J Mol Sci. 2021;22: pubmed publisher
Morozumi W, Aoshima K, Inagaki S, Iwata Y, Nakamura S, Hara H, et al. Piezo 1 is involved in intraocular pressure regulation. J Pharmacol Sci. 2021;147:211-221 pubmed publisher
Kulkarni S, Marquez J, Date P, Ventrella R, Mitchell B, Khokha M. Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells. elife. 2021;10: pubmed publisher
Miroshnikova Y, Manet S, Li X, Wickström S, Faurobert E, Albiges Rizo C. Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch. Mol Biol Cell. 2021;:mbcE21030106 pubmed publisher
Zhu B, Qian W, Han C, Bai T, Hou X. Piezo 1 activation facilitates cholangiocarcinoma metastasis via Hippo/YAP signaling axis. Mol Ther Nucleic Acids. 2021;24:241-252 pubmed publisher
Lee W, Nims R, Savadipour A, Zhang Q, Leddy H, Liu F, et al. Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Wang B, Ke W, Wang K, Li G, Ma L, Lu S, et al. Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration. Oxid Med Cell Longev. 2021;2021:8884922 pubmed publisher
Liu H, Bian W, Yang D, Yang M, Luo H. Inhibiting the Piezo1 channel protects microglia from acute hyperglycaemia damage through the JNK1 and mTOR signalling pathways. Life Sci. 2021;264:118667 pubmed publisher
Zhou W, Liu X, van Wijnbergen J, Yuan L, Liu Y, Zhang C, et al. Identification of PIEZO1 as a potential prognostic marker in gliomas. Sci Rep. 2020;10:16121 pubmed publisher
Song J, Liu L, Lv L, Hu S, Tariq A, Wang W, et al. Fluid shear stress induces Runx-2 expression via upregulation of PIEZO1 in MC3T3-E1 cells. Cell Biol Int. 2020;44:1491-1502 pubmed publisher
Smith J, Hart C, Ramos P, Akinsanya J, Lanza I, Joyner M, et al. Metabo- and mechanoreceptor expression in human heart failure: Relationships with the locomotor muscle afferent influence on exercise responses. Exp Physiol. 2020;105:809-818 pubmed publisher
He B, Johansson Percival A, Backhouse J, Li J, Lee G, Hamzah J, et al. Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy. Cell Rep. 2020;30:714-724.e5 pubmed publisher
Helmink B, Reddy S, Gao J, Zhang S, Basar R, Thakur R, et al. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020;577:549-555 pubmed publisher
Morozumi W, Inagaki S, Iwata Y, Nakamura S, Hara H, Shimazawa M. Piezo channel plays a part in retinal ganglion cell damage. Exp Eye Res. 2020;191:107900 pubmed publisher
Du G, Li L, Zhang X, Liu J, Hao J, Zhu J, et al. Roles of TRPV4 and piezo channels in stretch-evoked Ca2+ response in chondrocytes. Exp Biol Med (Maywood). 2020;245:180-189 pubmed publisher
Miyazaki A, Sugimoto A, Yoshizaki K, Kawarabayashi K, Iwata K, Kurogoushi R, et al. Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1. Sci Rep. 2019;9:14762 pubmed publisher
Matsubara S, Seki M, Suzuki S, Komori T, Takamori M. Tertiary lymphoid organs in the inflammatory myopathy associated with PD-1 inhibitors. J Immunother Cancer. 2019;7:256 pubmed publisher
Li X, Bean A, Uehara M, Banouni N, Ben Nasr M, Kasinath V, et al. Immune heterogeneity of head and tail pancreatic lymph nodes in non-obese diabetic mice. Sci Rep. 2019;9:9778 pubmed publisher
Uehara M, Li X, Sheikhi A, Zandi N, Walker B, Saleh B, et al. Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival. Sci Rep. 2019;9:6535 pubmed publisher
Bahmani B, Uehara M, Ordikhani F, Li X, Jiang L, Banouni N, et al. Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery. EBioMedicine. 2018;38:79-88 pubmed publisher
Bahmani B, Uehara M, Jiang L, Ordikhani F, Banouni N, Ichimura T, et al. Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival. J Clin Invest. 2018;128:4770-4786 pubmed publisher
Etem E, Ceylan G, Ozaydin S, Ceylan C, Ozercan I, Kuloglu T. The increased expression of Piezo1 and Piezo2 ion channels in human and mouse bladder carcinoma. Adv Clin Exp Med. 2018;27:1025-1031 pubmed publisher
Jiang L, Zhao Y, Chen W. The Function of the Novel Mechanical Activated Ion Channel Piezo1 in the Human Osteosarcoma Cells. Med Sci Monit. 2017;23:5070-5082 pubmed
Lee K, Guevarra M, Nguyen A, Chua M, Wang Y, Jacobs C. The primary cilium functions as a mechanical and calcium signaling nexus. Cilia. 2015;4:7 pubmed publisher
Hautz T, Zelger B, Nasr I, Mundinger G, Barth R, Rodriguez E, et al. Lymphoid neogenesis in skin of human hand, nonhuman primate, and rat vascularized composite allografts. Transpl Int. 2014;27:966-76 pubmed publisher
Hirakawa J, Tsuboi K, Sato K, Kobayashi M, Watanabe S, Takakura A, et al. Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing. J Biol Chem. 2010;285:40864-78 pubmed publisher
Burke S, Dong H, Hazan A, Croy B. Aberrant endometrial features of pregnancy in diabetic NOD mice. Diabetes. 2007;56:2919-26 pubmed
Drayton D, Ying X, Lee J, Lesslauer W, Ruddle N. Ectopic LT alpha beta directs lymphoid organ neogenesis with concomitant expression of peripheral node addressin and a HEV-restricted sulfotransferase. J Exp Med. 2003;197:1153-63 pubmed
Samulowitz U, Kuhn A, Brachtendorf G, Nawroth R, Braun A, Bankfalvi A, et al. Human endomucin: distribution pattern, expression on high endothelial venules, and decoration with the MECA-79 epitope. Am J Pathol. 2002;160:1669-81 pubmed
Csencsits K, Jutila M, Pascual D. Nasal-associated lymphoid tissue: phenotypic and functional evidence for the primary role of peripheral node addressin in naive lymphocyte adhesion to high endothelial venules in a mucosal site. J Immunol. 1999;163:1382-9 pubmed
product information
master code :
NBP1-78537
SKU :
NBP1-78537
product name :
PIEZO1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The PIEZO1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to PIEZO1. This antibody reacts with human,mouse,porcine,rat. The PIEZO1 Antibody - BSA Free has been validated for the following applications: Simple Western,IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vitro assay,Knockout Validated,Immunocytochemistry/ Immunofluorescence.
target :
PIEZO1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of the human PIEZO1 protein (between residues 1300-1350) [UniProt Q92508]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Porcine,Rat
gene symbol :
PIEZO1
accessionNumbers :
Q92508
applications :
Simple Western,IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vitro assay,Knockout Validated,Immunocytochemistry/ Immunofluorescence
USD :
459 USD
alt names :
FAM38A, member A, membrane protein induced by beta-amyloid treatment, Mib, piezo-type mechanosensitive ion channel component 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.