product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PIEZO1 Antibody - BSA Free
catalog :
NBP1-78446
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; dogs; 1:200; loading ...; fig s7a
Gudipaty S, Lindblom J, Loftus P, Redd M, Edes K, Davey C, et al. Mechanical stretch triggers rapid epithelial cell division through Piezo1. Nature. 2017;543:118-121 pubmed publisher
Liu C, Xia Y, Fu S, Meng F, Feng B, Xu L, et al. Inhibition of Piezo1 Ameliorates Intestinal Inflammation and Limits the Activation of Group 3 Innate Lymphoid Cells in Experimental Colitis. J Innate Immun. 2023;15:709-723 pubmed publisher
Zhao T, Chu Z, Chu C, Dong S, Li G, Wu J, et al. Macrophages induce gingival destruction via Piezo1-mediated MMPs-degrading collagens in periodontitis. Front Immunol. 2023;14:1194662 pubmed publisher
Mitchell S, Pardo Pastor C, Zangle T, Rosenblatt J. Voltage-dependent volume regulation controls epithelial cell extrusion and morphology. bioRxiv. 2023;: pubmed publisher
Hirano K, Tsuchiya M, Shiomi A, Takabayashi S, Suzuki M, Ishikawa Y, et al. The mechanosensitive ion channel PIEZO1 promotes satellite cell function in muscle regeneration. Life Sci Alliance. 2023;6: pubmed publisher
Foote A, Tibbetts J, Bartley S, Thibeault S. Localization of TRPV3/4 and PIEZO1/2 sensory receptors in murine and human larynges. Laryngoscope Investig Otolaryngol. 2022;7:1963-1972 pubmed publisher
Yao M, Tijore A, Cheng D, Li J, Hariharan A, Martinac B, et al. Force- and cell state-dependent recruitment of Piezo1 drives focal adhesion dynamics and calcium entry. Sci Adv. 2022;8:eabo1461 pubmed publisher
Greenlee J, Liu K, Lopez Cavestany M, King M. Piezo1 Mechano-Activation Is Augmented by Resveratrol and Differs between Colorectal Cancer Cells of Primary and Metastatic Origin. Molecules. 2022;27: pubmed publisher
Mylvaganam S, Plumb J, Yusuf B, Li R, Lu C, Robinson L, et al. The spectrin cytoskeleton integrates endothelial mechanoresponses. Nat Cell Biol. 2022;24:1226-1238 pubmed publisher
Harraz O, Klug N, Senatore A, Hill Eubanks D, Nelson M. Piezo1 Is a Mechanosensor Channel in Central Nervous System Capillaries. Circ Res. 2022;130:1531-1546 pubmed publisher
O Callaghan P, Engberg A, Eriksson O, Fatsis Kavalopoulos N, Stelzl C, Sanchez G, et al. Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells. J Cell Sci. 2022;135: pubmed publisher
Singh A, Tijore A, Margadant F, Simpson C, Chitkara D, Low B, et al. Enhanced tumor cell killing by ultrasound after microtubule depolymerization. Bioeng Transl Med. 2021;6:e10233 pubmed publisher
Bosutti A, Giniatullin A, Odnoshivkina Y, Giudice L, Malm T, Sciancalepore M, et al. "Time window" effect of Yoda1-evoked Piezo1 channel activity during mouse skeletal muscle differentiation. Acta Physiol (Oxf). 2021;233:e13702 pubmed publisher
Tijore A, Yao M, Wang Y, Hariharan A, Nematbakhsh Y, Lee Doss B, et al. Selective killing of transformed cells by mechanical stretch. Biomaterials. 2021;275:120866 pubmed publisher
Passini F, Jaeger P, Saab A, Hanlon S, Chittim N, Arlt M, et al. Shear-stress sensing by PIEZO1 regulates tendon stiffness in rodents and influences jumping performance in humans. Nat Biomed Eng. 2021;: pubmed publisher
Mitsuhata Y, Abe T, Misaki K, Nakajima Y, Kiriya K, Kawasaki M, et al. Cyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3. Sci Rep. 2021;11:5857 pubmed publisher
Zhang G, Li X, Wu L, Qin Y. Piezo1 channel activation in response to mechanobiological acoustic radiation force in osteoblastic cells. Bone Res. 2021;9:16 pubmed publisher
Lai A, Chen Y, Cox C, Jaworowski A, Peter K, Baratchi S. Analyzing the shear-induced sensitization of mechanosensitive ion channel Piezo-1 in human aortic endothelial cells. J Cell Physiol. 2021;236:2976-2987 pubmed publisher
Silver B, Wolf A, Lee J, Pang M, Nelson C. Epithelial tissue geometry directs emergence of bioelectric field and pattern of proliferation. Mol Biol Cell. 2020;31:1691-1702 pubmed publisher
Karakashev S, Fukumoto T, Zhao B, Lin J, Wu S, Fatkhutdinov N, et al. EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition. Cancer Cell. 2020;37:157-167.e6 pubmed publisher
Hope J, Lopez Cavestany M, Wang W, Reinhart King C, King M. Activation of Piezo1 sensitizes cells to TRAIL-mediated apoptosis through mitochondrial outer membrane permeability. Cell Death Dis. 2019;10:837 pubmed publisher
Jetta D, Gottlieb P, Verma D, Sachs F, Hua S. Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells. J Cell Sci. 2019;132: pubmed publisher
dela Paz N, Frangos J. Rapid flow-induced activation of Gαq/11 is independent of Piezo1 activation. Am J Physiol Cell Physiol. 2019;316:C741-C752 pubmed publisher
Mazzuoli Weber G, Kugler E, Bühler C, Kreutz F, Demir I, Ceyhan O, et al. Piezo proteins: incidence and abundance in the enteric nervous system. Is there a link with mechanosensitivity?. Cell Tissue Res. 2019;375:605-618 pubmed publisher
Xu H, Zhang L, Chen W, Xu J, Zhang R, Liu R, et al. Inhibitory effect of caveolin-1 in vascular endothelial cells, pericytes and smooth muscle cells. Oncotarget. 2017;8:76165-76173 pubmed publisher
Gilbert M, Goodman J, Gomez J, Johnstone A, Ramos R. Adult hippocampal neurogenesis is impaired by transient and moderate developmental thyroid hormone disruption. Neurotoxicology. 2017;59:9-21 pubmed publisher
Lin C, Zu C, Yang C, Tsai P, Shyu J, Chen C, et al. IL-1β-Induced Mesenchymal Stem Cell Migration Involves MLCK Activation via PKC Signaling. Cell Transplant. 2015;24:2011-28 pubmed publisher
product information
master code :
NBP1-78446
SKU :
NBP1-78446
product name :
PIEZO1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The PIEZO1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to PIEZO1. This antibody reacts with canine,guinea pig,human,mouse. The PIEZO1 Antibody - BSA Free has been validated for the following applications: Flow (Intracellular),Knockdown Validated,Immunocytochemistry/ Immunofluorescence,IF/IHC,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
PIEZO1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of the human PIEZO1 protein (between residues 950-1000) [UniProt Q92508]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Canine,Guinea Pig,Human,Mouse
gene symbol :
PIEZO1
accessionNumbers :
Q92508
applications :
IF/IHC,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
USD :
399 USD
alt names :
FAM38A, member A, membrane protein induced by beta-amyloid treatment, Mib, piezo-type mechanosensitive ion channel component 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.