product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mas Antibody - BSA Free
catalog :
NBP1-78444
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 36
Reference
Zhu C, Gu W, Sun D, Wei W. The mechanism underlying fluoride-induced low-renin hypertension is related to an imbalance in the circulatory and local renin-angiotensin systems. Toxicol Lett. 2023;381:36-47 pubmed publisher
Juretzko A, Steinbach A, Witte J, Hannemann A, Miehe B, Siegerist F, et al. Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy. Pflugers Arch. 2023;475:391-403 pubmed publisher
Matsunobe M, Motohashi N, Aoki E, Tominari T, Inada M, Aoki Y. Caveolin-3 regulates the activity of Ca2+/calmodulin-dependent protein kinase II in C2C12 cells. Am J Physiol Cell Physiol. 2022;323:C1137-C1148 pubmed publisher
Lamy G, Cafarchio E, do Vale B, Antonio B, Venancio D, de Souza J, et al. Unveiling the Angiotensin-(1-7) Actions on the Urinary Bladder in Female Rats. Front Physiol. 2022;13:920636 pubmed publisher
Gao Q, Chen R, Wu L, Huang Q, Wang X, Tian Y, et al. Angiotensin-(1-7) reduces α-synuclein aggregation by enhancing autophagic activity in Parkinson's disease. Neural Regen Res. 2022;17:1138-1145 pubmed publisher
Nguyen B, Yoshihara T, Deminice R, Lawrence J, Ozdemir M, Hyatt H, et al. Alterations in renin-angiotensin receptors are not responsible for exercise preconditioning of skeletal muscle fibers. Sports Med Health Sci. 2021;3:148-156 pubmed publisher
Dang R, Yang M, Cui C, Wang C, Zhang W, Geng C, et al. Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling. Aging Cell. 2021;20:e13480 pubmed publisher
Lamy G, Cafarchio E, do Vale B, Antonio B, Venancio D, de Souza J, et al. Lateral Preoptic Area Neurons Activated by Angiotensin-(1-7) Increase Intravesical Pressure: A Novel Feature in Central Micturition Control. Front Physiol. 2021;12:682711 pubmed publisher
Yoshihara T, Deminice R, Hyatt H, Ozdemir M, Nguyen B, Powers S. Angiotensin 1-7 protects against ventilator-induced diaphragm dysfunction. Clin Transl Sci. 2021;: pubmed publisher
Fan H, Bhullar K, Wu J. Spent Hen Muscle Protein-Derived RAS Regulating Peptides Show Antioxidant Activity in Vascular Cells. Antioxidants (Basel). 2021;10: pubmed publisher
Rudd S, Gad H, Sanjiv K, Amaral N, Hagenkort A, Groth P, et al. MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG. Cancer Res. 2020;: pubmed publisher
Moukengue B, Brown H, Charrier C, Battaglia S, Baud huin M, Quillard T, et al. TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases development in osteosarcoma model. EBioMedicine. 2020;53:102704 pubmed publisher
Bialkowski K, Kasprzak K. A profile of 8-oxo-dGTPase activities in the NCI-60 human cancer panel: Meta-analytic insight into the regulation and role of MTH1 (NUDT1) gene expression in carcinogenesis. Free Radic Biol Med. 2020;148:1-21 pubmed publisher
Dang Z, Su S, Jin G, Nan X, Ma L, Li Z, et al. Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat. J Ethnopharmacol. 2020;250:112470 pubmed publisher
Stone R, Liu S, Levy A, Kashani N, Louie S, Rodgers K, et al. Activation of the Protective Arm of the Renin Angiotensin System in Demyelinating Disease. J Neuroimmune Pharmacol. 2020;15:249-263 pubmed publisher
Cerniello F, Silva M, Carretero O, Gironacci M. Mas receptor is translocated to the nucleus upon agonist stimulation in brainstem neurons from spontaneously hypertensive rats but not normotensive rats. Cardiovasc Res. 2019;: pubmed publisher
Wang J, Nagy N, Masucci M. The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization. Oncogene. 2020;39:603-616 pubmed publisher
Cui C, Xu P, Li G, Qiao Y, Han W, Geng C, et al. Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system. Redox Biol. 2019;26:101295 pubmed publisher
McPherson L, Troccoli C, Ji D, Bowles A, Gardiner M, Mohsen M, et al. Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue. DNA Repair (Amst). 2019;83:102644 pubmed publisher
Zhou W, Ma L, Yang J, Qiao H, Li L, Guo Q, et al. Potent and specific MTH1 inhibitors targeting gastric cancer. Cell Death Dis. 2019;10:434 pubmed publisher
Pompsch M, Vogel J, Classen F, Kranz P, Iliakis G, Riffkin H, et al. The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia. BMC Cancer. 2018;18:1190 pubmed publisher
Mo J, Enkhjargal B, Travis Z, Zhou K, Wu P, Zhang G, et al. AVE 0991 attenuates oxidative stress and neuronal apoptosis via Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats. Redox Biol. 2019;20:75-86 pubmed publisher
Zou X, Owusu M, Harris R, Jackson S, Loizou J, Nik Zainal S. Validating the concept of mutational signatures with isogenic cell models. Nat Commun. 2018;9:1744 pubmed publisher
Ma X, Pang Z, Zhou J, He L, Hao Q, Li W, et al. Acetylation and Amination Protect Angiotensin 1-7 from Physiological Hydrolyzation and Therefore Increases Its Antitumor Effects on Lung Cancer. Mol Pharm. 2018;15:2338-2347 pubmed publisher
Fan J, Zhao R, Parro C, Zhao W, Chou H, Robert J, et al. Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway. J Lipid Res. 2018;59:830-842 pubmed publisher
Hashiguchi K, Hayashi M, Sekiguchi M, Umezu K. The roles of human MTH1, MTH2 and MTH3 proteins in maintaining genome stability under oxidative stress. Mutat Res. 2018;808:10-19 pubmed publisher
Page B, Valerie N, Wright R, Wallner O, Isaksson R, Carter M, et al. Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat Commun. 2018;9:250 pubmed publisher
Zhao S, Ghosh A, Lo C, Chenier I, Scholey J, Filep J, et al. Nrf2 Deficiency Upregulates Intrarenal Angiotensin-Converting Enzyme-2 and Angiotensin 1-7 Receptor Expression and Attenuates Hypertension and Nephropathy in Diabetic Mice. Endocrinology. 2018;159:836-852 pubmed publisher
Eshtad S, Mavajian Z, Rudd S, Visnes T, Bostrom J, Altun M, et al. hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia. Oncogenesis. 2016;5:e275 pubmed publisher
Zhou H, Jian Y, Leng Y, Liu N, Tian Y, Wang G, et al. Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma. Int J Hematol. 2017;105:318-325 pubmed publisher
Huber K, Olek K, Müller A, Tan C, Bennett K, Colinge J, et al. Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling. Nat Methods. 2015;12:1055-7 pubmed publisher
Carter M, Jemth A, Hagenkort A, Page B, Gustafsson R, Griese J, et al. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nat Commun. 2015;6:7871 pubmed publisher
Wheway G, Schmidts M, Mans D, Szymanska K, Nguyen T, Racher H, et al. An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nat Cell Biol. 2015;17:1074-1087 pubmed publisher
Giribaldi M, Muñoz A, Halvorsen K, Patel A, Rai P. MTH1 expression is required for effective transformation by oncogenic HRAS. Oncotarget. 2015;6:11519-29 pubmed
Bonora M, Wieckowsk M, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene. 2015;34:1608 pubmed publisher
Patel A, Burton D, Halvorsen K, Balkan W, Reiner T, Perez Stable C, et al. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. 2015;34:2586-96 pubmed publisher
product information
master code :
NBP1-78444
SKU :
NBP1-78444
product name :
Mas Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Mas Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Mas. This antibody reacts with human,mouse,primate,rabbit,rat. The Mas Antibody - BSA Free has been validated for the following applications: Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western.
target :
Mas
category :
Primary Antibodies
buffer :
PBS and 30% Glycerol
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide made to an internal portion of the human MAS1 protein (between residues 75-125) [Uniprot: P04201]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Primate,Rabbit,Rat
gene symbol :
MAS1
accessionNumbers :
P04201
applications :
Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Simple Western
USD :
409 USD
alt names :
MAS, MAS1 oncogene, MGC119966, proto-oncogene Mas
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.