product summary
request information :
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal TetR Antibody
catalog :
NBP1-78424F
quantity :
0.1 ml
price :
309.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
FITC
reactivity :
Escherichia coli
application :
western blot
more info or order :
Novus Biologicals product webpage
product information
Catalog Number :
NBP1-78424F
Product Name :
Rabbit Polyclonal TetR Antibody
List Price :
309.00 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
pSC101 tetR, Tet Repressor, Tet Repressor Protein, TetR, tetracycline repressor protein
Background :
Tetracycline repressor TetR (tetracycline repressor protein class B from transposon Tn10) belongs to the Tet/Cam family of bacterial regulators and it controls the expression of Tn10 encoded tetracycline resistance. When tetracycline is not present, TetR recognises its operator sequence, tetO, for repressing tetA expression (resistance gene) and its own expression. Upon entry into the cell, tetracycline binds a pocket within the protein core of TetR and induces a conformational change leading to reorientation of DNA binding heads, which in turn abolishes operator binding for triggering resistance gene expression. TetR repressed tetracycline resistance element is responsible for the maintenance of antibiotic resistance traits in strains of Escherichia coli which confers an advantage in selection to E. coli expressing tetracycline resistance. Moreover, TetR has attracted widespread interest because regulators belonging to this family control the expression of genes which are involved in development, fatty acid metabolism, drug resistance and many other cellular processes.
Buffer :
50mM sodium borate
Clonality :
Polyclonal
Conjugate :
FITC
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
A synthetic peptide made to an N-terminal portion of Escherichia coli TetR protein (between residues 1-50) [UniProt P04483]
Localization :
TetR peptide conserved in all strains of gram negative bacteria
Preservative :
No Preservative
Purity :
Immunogen affinity purified
CrossReactivity :
This antibody is used to monitor the regulation of gene expression in bacteria cells.
Storage :
Store at 4C in the dark.
Uses :
This TetR antibody is useful for Western blot.
Research Area :
Transcription Factors and Regulators
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.